Pharmacology News and Research

Latest Pharmacology News and Research

Navigating the Labyrinth of Traumatic Brain Injury to Discover a Secondary Neurological Condition

Working with individuals with traumatic brain injury (TBI) every day, I see the debilitating effects and long-term struggles firsthand.

9 Oct 2012

Trevena reports completion of TRV027 Phase 2a study in advanced heart failure patients

Trevena, Inc., the leader in the discovery and development of G-protein coupled receptor (GPCR) biased ligands, today announced that it has successfully completed a Phase 2a study on the hemodynamic effects of TRV027 in patients with advanced heart failure with reduced ejection fraction.

8 Oct 2012

Anesthetics and protein interactions: an interview with José A. Fernández

For a long time there was a controversy about how anesthetics work. The large number of molecules that have anesthetic properties (from benzodiazepines to nitrous oxide) and their very different structures...

8 Oct 2012

Nelfinavir inhibits growth of HER2-positive tumors

The HIV protease inhibitor, Nelfinavir, can be used to treat HER2-positive breast cancer in the same capacity and dosage regimen that it is used to treat HIV, according to a study published October 5 in the Journal of the National Cancer Institute.

6 Oct 2012

HIV transmission can be reduced by using opioid substitution treatments instead of injection drug use

People who inject drugs (PWID) can significantly reduce their risk of HIV infection with the use of opiate substitution treatments such as methadone, as suggested by an international team of researchers in a paper published today on bmj.com.

5 Oct 2012

New type of drug for drug-resistant cancer

New drug may be an effective alternative for patients whose cancer is resistant to currently available drugs.

4 Oct 2012

Paroxetine shows promise against heart failure

A medication usually used to help treat depression and anxiety disorders has the potential to help prevent heart failure, according to researchers at the University of Michigan.

2 Oct 2012

Researchers identify how p110delta molecule controls the body's inflammatory responses

Researchers at Queen Mary, University of London have discovered how a key molecule controls the body's inflammatory responses. The molecule, known as p110delta, fine-tunes inflammation to avoid excessive reactions that can damage the organism.

1 Oct 2012

Cholesterol precursor suppresses inflammatory response genes, causes atherosclerosis

Atherosclerosis - the hardening of arteries that is a primary cause of cardiovascular disease and death - has long been presumed to be the fateful consequence of complicated interactions between overabundant cholesterol and resulting inflammation in the heart and blood vessels.

28 Sep 2012

Fear hard to extinguish from the teenage brain

A new study by Weill Cornell Medical College researchers shows that adolescents' reactions to threat remain high even when the danger is no longer present. According to researchers, once a teenager's brain is triggered by a threat, the ability to suppress an emotional response to the threat is diminished which may explain the peak in anxiety and stress-related disorders during this developmental period.

28 Sep 2012

Efavirenz drug may play a key role in brain damage

The way the body metabolizes a commonly prescribed anti-retroviral drug that is used long term by patients infected with HIV may contribute to cognitive impairment by damaging nerve cells, a new Johns Hopkins research suggests.

28 Sep 2012

Study indicates the amounts paid by antipsychotic manufacturers to D.C. Medicaid psychiatrists

The D.C. Department of Health (DOH) has released a study by George Washington University School of Public Health & Health Services (SPHHS) indicating the high levels of marketing by antipsychotic drug manufacturers to Medicaid psychiatrists in the District of Columbia.

27 Sep 2012

Anxiety, depression and insomnia drugs and risk of driving accident: an interview with Hui-Ju Tsai

Anxiety, depression and insomnia drugs have been commonly used to treat mental and emotional disorders, or improve sleep-related problems.

27 Sep 2012

High concentrations of inhaled oxygen during and after cancer surgery may increase risk of death

Patients given high concentrations of inhaled oxygen during and after cancer surgery may be at higher long-term risk of death, according to a report in the October issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

26 Sep 2012

Resveratrol can maintain morphine’s pain-relieving effects

Resveratrol—the same natural polyphenol found in red wine—preserves the potent pain-relieving effect of morphine in rats that have developed morphine tolerance, suggests a study in the October issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

26 Sep 2012

Orexin-A hormone also affects emergence after anesthesia

A neuropeptide hormone called orexin-A—which plays an important role in regulating the normal sleep-wake cycle—also affects emergence (waking up) after anesthesia, reports an experimental study in the October issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

26 Sep 2012

UCSD evaluates safety and tolerability of dexanabinol in Phase I brain cancer study

Researchers at University of California, San Diego Moores Cancer Center are evaluating the safety and tolerability of a synthetic cannabinoid called dexanabinol (ETS2101). Delivered as a weekly intravenous infusion, the drug is being tested in patients with all forms of brain cancer, both primary and metastatic.

26 Sep 2012

Pharmacology News and Research

Latest Pharmacology News and Research

Navigating the Labyrinth of Traumatic Brain Injury to Discover a Secondary Neurological Condition

Trevena reports completion of TRV027 Phase 2a study in advanced heart failure patients

Anesthetics and protein interactions: an interview with José A. Fernández

Nelfinavir inhibits growth of HER2-positive tumors

HIV transmission can be reduced by using opioid substitution treatments instead of injection drug use

New type of drug for drug-resistant cancer

Paroxetine shows promise against heart failure

Researchers identify how p110delta molecule controls the body's inflammatory responses

Cholesterol precursor suppresses inflammatory response genes, causes atherosclerosis

Fear hard to extinguish from the teenage brain

Efavirenz drug may play a key role in brain damage

Study indicates the amounts paid by antipsychotic manufacturers to D.C. Medicaid psychiatrists

Anxiety, depression and insomnia drugs and risk of driving accident: an interview with Hui-Ju Tsai

High concentrations of inhaled oxygen during and after cancer surgery may increase risk of death

Resveratrol can maintain morphine’s pain-relieving effects

Orexin-A hormone also affects emergence after anesthesia

UCSD evaluates safety and tolerability of dexanabinol in Phase I brain cancer study

Insufficient evidence to support medical intervention use in young adults with autism

Wiley announces publication of 6-volume Encyclopedia of Drug Metabolism and Interactions

FDA forms new internal task force to support development of new antibacterial drugs

Pittcon Highlights: Pharmaceutical & Biologic eBook

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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