Pharmacology News and Research

Latest Pharmacology News and Research

Apolipoprotein E gene raises newborns' cerebral palsy risk

Apolipoprotein E (APOE), a gene associated with heightened risk for Alzheimer's disease in adults, can also increase the likelihood that brain-injured newborns will develop cerebral palsy, researchers at Children's Memorial Research Center have discovered.

5 Feb 2007

Institute of Materia Medica and TB Alliance partner to tackle tuberculosis

The Institute of Materia Medica (IMM), a member of the Chinese Academy of Medical Sciences, and the Global Alliance for TB Drug Development (TB Alliance), a not-for-profit, product development partnership accelerating the discovery and development of new TB drugs, today announced plans to pursue a joint research partnership to develop promising, novel anti-tuberculosis agents.

31 Jan 2007

RNA used to turn on genes to alleviate disease

A new technique that employs RNA, a tiny chemical cousin of DNA, to turn on genes could lead to therapeutics for conditions in which nudging a gene awake would help alleviate disease, researchers at UT Southwestern Medical Center say.

28 Jan 2007

Spinal cord uses network mechanisms similar to those used in the brain

Our findings contradict conventional wisdom about spinal cord functions, says Rune W. Berg from Department of Neuroscience and Pharmacology at the Faculty of Health Sciences.

23 Jan 2007

Research offers hope for alcoholics

Scientists at Melbourne's Howard Florey Institute have discovered a system in the brain that stops an alcoholic's craving for alcohol, as well as prevent relapse once they have recovered from alcohol addiction.

12 Dec 2006

Cancer Research Technology and University of Manchester announce collaboration in oncology with AstraZeneca

Cancer Research Technology Limited (CRT), the oncology-focused development and commercialisation company, and The University of Manchester have entered into an agreement with AstraZeneca to establish a clinical pharmacology biomarker research and discovery collaboration.

20 Nov 2006

Safety of t-PA clot-busting therapy questioned

Across the world, emergency medical teams often administer a powerful clot-busting drug called tissue plasminogen activator (t-PA) to help patients stricken by heart attack.

13 Nov 2006

Scientists spot mechanism behind promising new sleep drug

An experimental drug called gaboxadol may soon help millions of bleary-eyed insomniacs get to sleep, and a multi-center team of U.S. scientists believes they've pinpointed just how the drug works.

1 Nov 2006

Blood clotting protein appears to also play a role in fertility

A protein known to play a role in blood clotting and other cell functions is also critical for proper sperm formation in mice, according to researchers from the University of North Carolina at Chapel Hill School of Medicine.

20 Oct 2006

FDA advisory panel recommends adding warning label to Tamoxifen

An FDA advisory panel on Wednesday recommended that a warning label be added to tamoxifen, an agency-approved drug for treating and preventing breast cancer, the AP/Seattle Post-Intelligencer reports (Bridges, AP/Seattle Post-Intelligencer, 10/18).

19 Oct 2006

Acne drug leads to depression-related behavior in mice

A drug commonly used to treat severe acne can lead to depression-related behavior in mice, according to research published in the journal Neuropsychopharmacology by scientists from The University of Texas at Austin and the University of Bath.

21 Sep 2006

Acne drug Roaccutane linked to depression

A drug commonly used to treat severe acne can lead to depressive behaviour in mice, according to research published in the journal Neuropsychopharmacology.

19 Sep 2006

New sunscreen ingredient that actively repairs sunburnt skin

People who suffer from sunburn could soon benefit from a new sunscreen ingredient that actively repairs sunburnt skin and helps prevent the onset of skin cancer, according to research published in the Journal of Investigative Dermatology.

7 Sep 2006

New test for acetaminophen poisoning

A new test for acetaminophen poisoning is effective with children as well as adults, according to a study published this month by researchers at the University of Arkansas for Medical Sciences (UAMS) and the Arkansas Children's Hospital Research Institute (ACHRI).

5 Sep 2006

Scientists identify novel central nervous system proteins affected by chronic alcohol exposure

Researchers at the University at Buffalo studying the effects of alcohol on the brain, using zebrafish as a model, have identified several novel central nervous system proteins that are affected by chronic alcohol exposure.

31 Aug 2006

Newly discovered molecular motor helps a cell determine which way is up

The sense of top and bottom is often lost in cells that become cancerous and may be an important factor in metastasis.

30 Aug 2006

Racial differences in hepatitis C viral responses

African American patients with hepatitis C (HCV) infections experience a lower response rate to the peginterferon alfa-2a and ribavirin combination treatment than Caucasian Americans, according to a study published in the August issue of Gastroenterology.

16 Aug 2006

New tool to study protein kinase A - linked to heart failure

Scientists studying heart cells have devised a new way to visualize and quantify the rise and fall in the activity of a key enzyme linked to heart failure.

8 Aug 2006

Methamphetamine increases production of protein that promotes the spread of the HIV-1 virus in infected drug users

Researchers at the University at Buffalo have presented the first evidence that the addictive drug methamphetamine, or meth, also commonly known as "speed" or "crystal," increases production of a docking protein that promotes the spread of the HIV-1 virus in infected users.

4 Aug 2006