Pharmacology News and Research

Latest Pharmacology News and Research

Drug shortfall as more than 5,000 conditions need medication

Only seven per cent of drug applications for treating people with rare diseases were approved in Europe between 2000 and 2004, despite the fact that there are currently more than 5,000 conditions needing medication.

9 Mar 2006

5,000 rare diseases need drugs, but Europe only approves a handful each year

6 Mar 2006

Data from Novogen inflammatory bowel disease drug Phase I clinical trial shows promise

A recently completed Phase 1 clinical trial of an investigational drug to treat inflammatory bowel disease has demonstrated rapid absorption indicating potential for development as an oral therapy.

6 Mar 2006

Scientists show how MRSA sidesteps hospital protection measures

The MRSA 'superbug' evades many of the measures introduced to combat its spread by infecting a common single-celled organism found almost everywhere in hospital wards, according to new research published in the journal Environmental Microbiology.

1 Mar 2006

Ancient DNA helps unearth potential hemophilia therapy

A cut can be life-threatening for people with hemophilia, whose bodies don't produce enough of a protein that prevents prolonged bleeding.

1 Mar 2006

Compound found in marijuana may defend against diabetic retinopathy

A compound found in marijuana won't make you high but it may help keep your eyes healthy if you're a diabetic, researchers say.

1 Mar 2006

Medical research must put public interests before commercial decisions

Doctors employed by pharmaceutical companies must always put the best interests of patients before their medical research, even if it brings them into conflict with their employers, according to new practical advice from the Faculty of Pharmaceutical Medicine published in the February issue of International Journal of Clinical Practice (IJCP).

21 Feb 2006

New mechanism that regulates K-Ras - protein that plays an important role in cancer

Researchers have discovered a protein widely known to cause the out-of-control growth of cells can actually be manipulated to induce those cells to commit suicide, providing a novel target for the development of anti-cancer drugs, according to the results of a new study led by New York University School of Medicine researchers.

21 Feb 2006

Potential new drug for treating all forms of tuberculosis

An experimental tuberculosis drug may be effective against not only multi drug-resistant forms of the disease but could also be the first compound to treat the latent stage of infection as well. Researchers reported their results at the 2006 ASM Biodefense Research Meeting.

20 Feb 2006

Children given lower doses of adult drugs at risk of harmful side effects

A new study has provided the strongest and most comprehensive evidence yet of the difference between how adults and infants and children process drugs.

19 Feb 2006

Ovarian cancer responds to aspirin and chemotherapy drug cisplatin

A new study using ovarian cancer cell lines shows promise in treating the deadly disease by combining the chemotherapy drug cisplatin with an aspirin-like compound to make recurrent cancer cells less resistant to the chemotherapy.

17 Feb 2006

Dramatic metabolic differences in how people process drugs

A Medical College of Wisconsin study provides the strongest and most complete evidence to date of major changes occurring during human development in the types and levels of enzymes responsible for the disposition of drugs and environmental chemicals.

17 Feb 2006

Panorama programme lead to significant increase in adverse paroxetine reports

The number of adverse reactions reported by UK doctors to the antidepressant paroxetine - often know by its brand name Seroxat - rose by 61 per cent after three editions of the BBC's award-winning current affairs programme Panorama explored increasing concerns about the drug.

14 Feb 2006

FDA affirms safety of Aspartame

The Calorie Control Council has stated that a rat study conducted by Italy's Ramazzini Institute is totally contradictory to the extensive scientific research and regulatory reviews conducted on aspartame. The U.S. Food & Drug Administration (FDA) has said they are not recommending any changes in the use of aspartame.

13 Feb 2006

Protein associated with growth of tumors may prevent the spread of cancer

A protein associated with the growth of head and neck tumors may be a tumor suppressor that could prevent the spread of cancer when it is expressed above normal levels, according to a study published in the Journal of the National Cancer Institute (JNCI).

13 Feb 2006

Chink in cancer's armor

Much as the famed starship Enterprise would deploy a deflector shield to evade enemy attack, tumor cells are capable of switching on a molecular force field of their own to fend off treatments aimed at killing them. Now University of Florida researchers have found a chink in their armor.

13 Feb 2006

Gut protein protects against infection and intestinal breakdown

A protein that binds to bile in the small intestine may hold the key to preventing infection and intestinal breakdown in people with conditions such as obstructive jaundice or irritable bowel syndrome, researchers at UT Southwestern Medical Center have discovered.

12 Feb 2006

Study shows one third of candidates are unlikely to benefit from ICD

Last year, about 170,000 people in North America had devices surgically implanted to stop potentially fatal arrhythmias. For many, these were life-saving, but for others they were unnecessary, uncomfortable, and sometimes dangerous.

7 Feb 2006

Intracellular observation of RNA metabolism will help identify disease-associated RNAs

For the first time, researchers can now peer inside intact cells to not only identify RNA-binding proteins, but also observe-in real-time-the intricate activities of these special molecules that make them key players in managing some of the cell's most basic functions.

7 Feb 2006

Symposium on celiac disease

A scientific symposium on celiac disease, "Genetic and Immune Mechanisms in Celiac Disease," will be held at the University of California, San Diego (UCSD) School of Medicine on Friday, February 10, from 8:30 a.m. to 12 noon. The symposium, hosted by UCSD’s newly established William K. Warren Medical Research Center for Celiac Disease, will be held at the university’s Center for Molecular Genetics conference room.

23 Jan 2006