Pharmacology News and Research

Latest Pharmacology News and Research

Controlling the expression of genes by turning them on or off could produce a drug for the treatment or cure of almost any disease

A new technique aimed at directly controlling the expression of genes by turning them on or off at the DNA level could lead to drugs for the treatment or cure of many diseases, say researchers at UT Southwestern Medical Center.

1 Aug 2005

Researchers reveal secret of key protein in brain and heart function

Brown University biologists have solved the structure of a critical piece of synapse-associated protein 97 (SAP97) found in abundance in the heart and head, where it is believed to play a role in everything from cardiac contractions to memory creation. Results are published in The Journal of Biological Chemistry.

31 Jul 2005

Cancer biology, pharmacology and engineering combine to create cancer smart bomb

Imagine a cancer drug that can burrow into a tumor, seal the exits and detonate a lethal dose of anti-cancer toxins, all while leaving healthy cells unscathed.

27 Jul 2005

Single prenatal dose of methamphetamine enough to cause long-term neurodevelopmental problems in babies

In research published in the August issue of Free Radical Biology and Medicine, U of T pharmacy and pharmacology professor Peter Wells and his colleagues determined that exposing pregnant mice only once to methamphetamine led to delivery of offspring with long-term neurodevelopmental problems, including reduced motor co-ordination.

26 Jul 2005

Innovation that helps locate and treat life-threatening heart arrhythmias

The Research Foundation of SUNY, which supports the advancement of education, research and discovery at the State University of New York, today announced it signed a licensing agreement with Biosense Webster Inc. for the rights to an Upstate Medical University innovation that helps locate and treat life-threatening heart arrhythmias.

26 Jul 2005

Multiple rare mutations within a single gene may increase risk for autism

While debate still rages over the 'cause' of autism, mounting evidence suggests that genetic factors play a major role in the disease.

25 Jul 2005

Study provides evidence that hormone treatments can be beneficial to limiting cardiovascular ailments

UC Irvine School of Medicine researchers have identified how estrogen helps prevents a cardiac ailment often seen in women who have heart attacks. This research provides further evidence that hormone replacement therapy after menopause can help prevent certain forms of cardiovascular disease in women.

19 Jul 2005

U.S. Senate approves Crawford for FDA commissioner

The nomination of Lester Crawford as permanent commissioner of the Food and Drug Administration (FDA), was overwhelmingly approved by the U.S. Senate on Monday.

19 Jul 2005

Compound derived from cottonseed could help improve the effectiveness of chemotherapy at treating head and neck cancer

The findings, which appear in the July issue of the journal Molecular Cancer Therapeutics, could lead to a treatment that provides an effective option to surgically removing the cancer, helping patients preserve vital organs involved in speech and swallowing.

18 Jul 2005

Way now clear for FDA approval of Plan B "morning-after" pill

Now that senators Patty Murray of Washington and Hillary Clinton of New York, have dropped their objections to acting FDA Commissioner Lester Crawford becoming the permanent commissioner, approval for the sale of the Plan B "morning-after" contraceptive without a prescription should be granted with the minimum of delay.

18 Jul 2005

Keap1 protein - a promising new target for drugs to fight many different kinds of cancer

Researchers at the University of Illinois at Chicago are unraveling the biochemical mechanism by which functional foods combat cancer.

11 Jul 2005

Findings shed light on the underlying mechanisms that cause hypertension

An enzyme known to cause hypertension increases blood pressure by activating tiny pores, or channels, in kidney cells that allow increased levels of sodium to be reabsorbed into the blood, researchers at UT Southwestern Medical Center have found.

6 Jul 2005

Old skin fungus drug has been found to be a possible cancer treatment

A drug that has been used for 40 years for the treatment of skin fungus has been found to be a possible cancer treatment, according to an international team of scientists. Leslie Wilson, professor of biochemistry and pharmacology at the University of California, Santa Barbara, said that the antifungal drug, griseofulvin, has been shown to inhibit the growth of cancer cells in his laboratory.

30 Jun 2005

Saturated fats combined with genetic trait may make people more susceptible to type 2 diabetes

A University of Alberta team of researchers has discovered an additional 2 million Canadians who have a high fat diet or are overweight may be at increased risk for developing type 2 diabetes if they carry a particular type of common specific genetic trait known as a polymorphism.

29 Jun 2005

New research raises the possibility that the risk of developing arsenic-related disease is not the same for everybody

Children with a particular variation in the CYT19 gene metabolize arsenic differently than adults with the same genetic variant, according to a new research report. The findings have important implications for the safety of drinking water worldwide and the use of arsenic as a cancer drug.

27 Jun 2005

Obesity is associated with an impairment of coronary circulatory function

A team of University of California, Los Angeles researchers found that positron emission tomography (PET) can provide important information on the relationship between heart function and obesity. Their findings were reported at the Society of Nuclear Medicine's 52nd Annual Meeting June 18–22 in Toronto.

20 Jun 2005

PET might be a promising tool for early prediction of response to chemotherapy for ovarian can

Noninvasive positron emission tomography (PET) imaging may allow earlier prediction of a patient's response to chemotherapy for ovarian cancer, according to research reported at the Society of Nuclear Medicine's 52nd Annual Meeting June 18–22 in Toronto.

20 Jun 2005

Fine tuning drug levels in neuroblastoma patients is effective

Monitoring and fine tuning the levels of the cancer drug topotecan in children with neuroblastoma holds promise for maximizing the drug's effectiveness while reducing its toxicity, according to investigators at St. Jude Children's Research Hospital.

19 Jun 2005

Fine tuning drug levels in neuroblastoma patients is effective

16 Jun 2005

Rimonabant study shows significant improvements in HbA1c and cardiometabolic risk factors in people with type 2 diabetes

The reported results of a one-year phase III study in 1045 people with type 2 diabetes treated with rimonabant, the first in a new class of therapeutic agents called selective CB1 Blockers, were that rimonabant 20 mg significantly improved HbA1c (a measure of blood sugar control), dyslipidemia (abnormal levels of fat in the blood), and systolic blood pressure with a concomitant substantial reduction in abdominal obesity in people with type 2 diabetes treated with oral anti-diabetic medications and requiring further control.

12 Jun 2005

Pharmacology News and Research

Latest Pharmacology News and Research

Controlling the expression of genes by turning them on or off could produce a drug for the treatment or cure of almost any disease

Researchers reveal secret of key protein in brain and heart function

Cancer biology, pharmacology and engineering combine to create cancer smart bomb

Single prenatal dose of methamphetamine enough to cause long-term neurodevelopmental problems in babies

Innovation that helps locate and treat life-threatening heart arrhythmias

Multiple rare mutations within a single gene may increase risk for autism

Study provides evidence that hormone treatments can be beneficial to limiting cardiovascular ailments

U.S. Senate approves Crawford for FDA commissioner

Compound derived from cottonseed could help improve the effectiveness of chemotherapy at treating head and neck cancer

Way now clear for FDA approval of Plan B "morning-after" pill

Keap1 protein - a promising new target for drugs to fight many different kinds of cancer

Findings shed light on the underlying mechanisms that cause hypertension

Old skin fungus drug has been found to be a possible cancer treatment

Saturated fats combined with genetic trait may make people more susceptible to type 2 diabetes

New research raises the possibility that the risk of developing arsenic-related disease is not the same for everybody

Obesity is associated with an impairment of coronary circulatory function

PET might be a promising tool for early prediction of response to chemotherapy for ovarian can

Fine tuning drug levels in neuroblastoma patients is effective

Fine tuning drug levels in neuroblastoma patients is effective

Rimonabant study shows significant improvements in HbA1c and cardiometabolic risk factors in people with type 2 diabetes

Pittcon Highlights: Pharmaceutical & Biologic eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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