Pharmacology News and Research

Latest Pharmacology News and Research

Potentially inappropriate prescribing linked to functional decline in older adults

Individuals are often prescribed increasing numbers of medications as they age, and while many of these prescriptions are justifiable, some may be inappropriate.

19 May 2021

Researchers use base editing to sustainably lower high LDL cholesterol levels

Base editing is a novel gene editing approach that can precisely change individual building blocks in a DNA sequence.

19 May 2021

Researchers develop integrative approach to better understand the origins of Parkinson's disease

Parkinson's disease is the second most common neurodegenerative disease and affects more than 10 million people around the world.

19 May 2021

Sequentia collaborated with Nextbiomics to obtain a novel immunization model against COVID-19

Sequentia Biotech and NextBiomics announced the filing of a patent application for a bacterial vaccine against the COVID-19 syndrome.

From Sequentia Biotech 19 May 2021

Researchers report promising biotherapeutics for obesity and related medical complications

The research teams at the University of Hong Kong led by Professor Xuechen LI from the Research Division for Chemistry and Department of Chemistry, and Professor Yu WANG from the Department of Pharmacology and Pharmacy, reported a synthetic biotherapeutics with promising anti-tumor, insulin sensitising and hepatoprotective activities in the Journal of the American Chemical Society.

18 May 2021

What can ancient feces tell us about the evolution of the human gut microbiome?

Researchers at the Section on Pathophysiology and Molecular Pharmacology, Joslin Diabetes Center in Boston, Massachusetts, analyzed microbial DNA found in indigenous human paleofeces (desiccated excrement) from dry caves in northern Mexico and Utah. They found that the ancient human gut microbiome is similar to those of modern-day people from non-industrialized populations.

14 May 2021

Normalizing cholesterol metabolism in microglia alleviates chronic neuropathic pain

Chemotherapy can induce a painful peripheral neuropathy (CIPN), a chronic condition and common adverse effect for cancer patients undergoing treatment.

10 May 2021

$Hospitalized COVID-19 patients with impaired first-phase ejection fraction have higher death risk$

Hospitalized COVID-19 patients with impaired first-phase ejection fraction have higher death risk

Hospitalized COVID-19 patients with impaired first-phase ejection fraction were nearly 5 times more likely to die compared to patients with healthier measures of this early, often undetected sign of heart failure, according to new research published today in Hypertension, an American Heart Association journal.

10 May 2021

Novel CBD analog alleviates pain in mouse model of chemotherapy-induced peripheral neuropathy

For patients with chronic pain, ineffective treatments, lowered work productivity, and other factors often coalesce, fueling feelings of hopelessness and anxiety and setting the stage for even bigger problems, including substance use disorders.

5 May 2021

Repurposing an existing, cheap drug into long-acting injectable therapy to treat Covid-19

Researchers from the University of Liverpool have shown the potential of repurposing an existing and cheap drug into a long-acting injectable therapy that could be used to treat Covid-19.

5 May 2021

New genetic mutation increases risk for atrial fibrillation, heart failure in Black people

A new mutation found in a gene associated with an increased risk of atrial fibrillation poses a significantly increased risk for heart failure in Black people.

5 May 2021

New insights on how hospitalized patients develop liver injury from taking different drugs

A new study published in the British Journal of Clinical Pharmacology provides insights on how common hospitalized patients develop liver injury from taking different medications.

5 May 2021

Study identifies novel combination therapy to help patients with advanced lung cancer

A new study by researchers at the UCLA Jonsson Comprehensive Cancer Center has identified a novel combination therapy to potentially help overcome resistance to immunotherapy in people diagnosed with advanced lung cancer.

5 May 2021

Experts create evidence-informed guidance for nutritional care of preterm infants

A hot topic symposia session during the Pediatric Academic Societies (PAS) 2021 Virtual Meeting will address the persistent controversies and questions in preterm infant nutrition.

5 May 2021

Multiple cycles through the dishwasher most effective at removing BPA from Tritan bottles

As part of a laboratory experiment, Rebecca Holmes examined water bottles that had been acquired from abroad expecting to find bisphenol A (BPA), a human-made component commonly found in polycarbonate plastics used to make consumer products.

30 Apr 2021

Researchers identify potential therapeutic target to prevent neurodegeneration after a stroke

Researchers with the Peter O'Donnell Jr. Brain Institute at UT Southwestern have identified a new protein implicated in cell death that provides a potential therapeutic target that could prevent or delay the progress of neurodegenerative diseases following a stroke.

27 Apr 2021

Some heart medications may facilitate SARS-CoV-2 infection through increasing ACE2 receptor levels

An interesting poster, just presented at the annual meeting of the American Society for Pharmacology and Experimental Therapeutics 2021, reports an association between the use of certain heart medications and the risk of COVID-19.

27 Apr 2021

Regulatory protein in skeletal muscle fiber may play a key role in the body's fight or flight response

Researchers at the University of Cincinnati say a regulatory protein found in skeletal muscle fiber may play an important role in the body's fight or flight response when encountering stressful situations.

23 Apr 2021

New imaging technique captures movies of receptors on the surface of living cells

A new imaging technique developed by scientists at Columbia University Vagelos College of Physicians and Surgeons and St. Jude Children's Research Hospital captures movies of receptors on the surface of living cells in unprecedented detail and could pave the way to a trove of new drugs.

23 Apr 2021

Bath scientists receive £1.3 million grant to develop a portable spice-detection device

University of Bath scientists have been awarded a research grant of £1.3 million to develop a portable device to detect the street drug ‘spice’ on the spot. They expect the new technology to be ready for use in clinical settings, prisons and across police services within three years.

22 Apr 2021

Pharmacology News and Research

Latest Pharmacology News and Research

Potentially inappropriate prescribing linked to functional decline in older adults

Researchers use base editing to sustainably lower high LDL cholesterol levels

Researchers develop integrative approach to better understand the origins of Parkinson's disease

Sequentia collaborated with Nextbiomics to obtain a novel immunization model against COVID-19

Researchers report promising biotherapeutics for obesity and related medical complications

What can ancient feces tell us about the evolution of the human gut microbiome?

Normalizing cholesterol metabolism in microglia alleviates chronic neuropathic pain

Hospitalized COVID-19 patients with impaired first-phase ejection fraction have higher death risk

Novel CBD analog alleviates pain in mouse model of chemotherapy-induced peripheral neuropathy

Repurposing an existing, cheap drug into long-acting injectable therapy to treat Covid-19

New genetic mutation increases risk for atrial fibrillation, heart failure in Black people

New insights on how hospitalized patients develop liver injury from taking different drugs

Study identifies novel combination therapy to help patients with advanced lung cancer

Experts create evidence-informed guidance for nutritional care of preterm infants

Multiple cycles through the dishwasher most effective at removing BPA from Tritan bottles

Researchers identify potential therapeutic target to prevent neurodegeneration after a stroke

Some heart medications may facilitate SARS-CoV-2 infection through increasing ACE2 receptor levels

Regulatory protein in skeletal muscle fiber may play a key role in the body's fight or flight response

New imaging technique captures movies of receptors on the surface of living cells

Bath scientists receive £1.3 million grant to develop a portable spice-detection device

Industry Focus - Biopharma eBook

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Pharmacology News and Research

Latest Pharmacology News and Research

Industry Focus - Biopharma eBook

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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