Rheumatoid Arthritis News and Research

Latest Rheumatoid Arthritis News and Research

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

AbbVie today announced the European Medicines Agency's (EMA) Committee for Medicinal Products for Human Use (CHMP) recommended the approval of upadacitinib (RINVOQ® 15 mg, once daily) for the treatment of active non-radiographic axial spondyloarthritis (nr‑axSpA) in adult patients with objective signs of inflammation as indicated by elevated C-reactive protein (CRP) and/or magnetic resonance imaging (MRI), who have responded inadequately to nonsteroidal anti-inflammatory drugs (NSAIDs).*

27 Jun 2022

COVID-19 outcomes improved for SARDs patients through Omicron wave

In a recent study posted to the medRxiv* pre-print server, researchers investigated coronavirus disease 2019 (COVID-19) incidence and severity among systemic autoimmune rheumatic diseases (SARDs) patients in Massachusetts, United States (US), between March 1, 2020, and January 31, 2022.

22 Jun 2022

Risk of severe COVID-19 in adults with immune-mediated inflammatory diseases and those on immune-modifying therapies

Researchers assessed the risk of severe COVID-19 in adults with immune-mediated inflammatory diseases and those on immunomodulatory therapies.

13 Jun 2022

People with inflammatory immune conditions had increased risk of COVID-19-related death before vaccination

People with certain inflammatory immune conditions affecting the joints, bowel and skin, such as rheumatoid arthritis, may have been more at risk of dying or needing hospital care if they got COVID-19 before vaccination compared with the general population, according to a new study published in The Lancet Rheumatology.

9 Jun 2022

Study identifies an epigenetic regulator that suppresses pathogenic events in rheumatoid arthritis

Rheumatoid arthritis (RA) is characterized by chronic inflammation of synovium, eventually leading to joint destruction. Epigenetic alteration (the mechanism of gene expression regulation without DNA sequence changes), such as low levels of DNA methylation, is one of the factors which worsens the RA state.

8 Jun 2022

Computer vision tool effectively distinguishes rheumatoid arthritis from osteoarthritis in joint tissue

A new study led by Hospital for Special Surgery investigators in New York City has found that their computer vision tool effectively distinguishes rheumatoid arthritis (RA) from osteoarthritis (OA) in joint tissue taken from patients who underwent total knee replacement (TKR).

3 Jun 2022

New HSS study clarifies the clinical manifestations of undifferentiated connective tissue disease

A new study by researchers at Hospital for Special Surgery (HSS) has further clarified the clinical manifestations of undifferentiated connective tissue disease (UCTD).

2 Jun 2022

ASU study explores components of the immune system

Unless you are an identical twin, you probably aren't often mistaken for someone else. Likewise, our own sense of self as distinct from all other humans is deeply ingrained since early childhood.

2 Jun 2022

Researchers show how electrical stimulation of the vagus nerve in inflammation promotes healing

The nervous system is known to communicate with the immune system and regulate inflammation in the body. Researchers at Karolinska Institutet in Sweden now show how electrical activation of a specific nerve can promote healing in acute inflammation.

31 May 2022

After SARS-CoV-2 infection, anti-chemokine antibodies correlate with better outcomes

A recent study posted to the bioRxiv* preprint server illustrated that specific chemokine antibodies aid in recognizing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) convalescent individuals with a desirable disease course.

26 May 2022

Olverembatinib a potent inhibitor of Omicron NTD-mediated cytokine release

Researchers determine whether mutations in the Omicron NTD influence its potential to stimulate myeloid cells and enhance inflammatory cytokine release.

22 May 2022

Molecular profiling of diseased joints could transform treatment for rheumatoid arthritis patients

New research from Queen Mary University of London, published in Nature Medicine, has shown that molecular profiling of the diseased joint tissue can significantly impact whether specific drug treatments will work to treat rheumatoid arthritis (RA) patients.

19 May 2022

Patients, doctors, insurers agree: Prior approvals for treatment should come faster

Andrew Bade, who was diagnosed with Type 1 diabetes nearly two decades ago, is accustomed to all the medical gear he needs to keep his blood sugar under control.

17 May 2022

New AI tool can speed up the diagnosis of psoriatic arthritis by up to 4 years

Researchers in Israel have shown that a new machine-learning tool can speed up the diagnosis of psoriatic arthritis (PsA) by up to 4 years, potentially preventing irreversible joint damage and deteriorating function for sufferers.

15 May 2022

Enzyme discovery offers new way to regulate cell death process for inflammatory diseases

A WEHI-led study has identified a new enzyme involved in controlling cell death, in findings that could lead to better treatment options for a range of inflammatory conditions, cancers and viruses.

12 May 2022

Study estimates effectiveness of 2-dose and 3-dose mRNA vaccination against Omicron

In a recent study posted to the medRxiv* preprint server, researchers estimated the efficacy of two-dose and three-dose regimens of two messenger ribonucleic acid (mRNA) vaccines: Moderna’s mRNA-1273 and Pfizer-BioNTech’s BNT162b2 against coronavirus disease 2019 (COVID-19) caused due to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant.

12 May 2022

Report highlights the need for an office to support autoimmune disease research across NIH institutes

While the quantity and quality of research that the National Institutes of Health (NIH) conducts on autoimmune diseases is impressive, a strategic plan and a well-funded office to support the coordination of all autoimmune disease research across NIH institutes and centers are needed, says a new congressionally mandated report from the National Academies of Sciences, Engineering, and Medicine.

10 May 2022

Detecting treatments for autoimmune disease using an immune ‘fingerprint’

In this interview, we speak to Professor Joseph Powell about his latest research that investigated the use of immune 'fingerprints' to treat autoimmune disease.

10 May 2022

Urgent action needed to address disparities in women’s heart health

Investing in and improving research, awareness and equity in women's heart health are critical for the health and well-being of women, according to a new Presidential Advisory from the American Heart Association, published today in the Association's flagship journal Circulation.

9 May 2022

Novel genetic mapping study traces links between DNA variations and blood proteins

A new genetic mapping study led by researchers at the Johns Hopkins Bloomberg School of Public Health traces links between DNA variations and thousands of blood proteins in two large and distinct populations. The results should help researchers better understand the molecular causes of diseases and identify proteins that could be targeted to treat these diseases.

3 May 2022

Rheumatoid Arthritis News and Research

Latest Rheumatoid Arthritis News and Research

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

COVID-19 outcomes improved for SARDs patients through Omicron wave

Risk of severe COVID-19 in adults with immune-mediated inflammatory diseases and those on immune-modifying therapies

People with inflammatory immune conditions had increased risk of COVID-19-related death before vaccination

Study identifies an epigenetic regulator that suppresses pathogenic events in rheumatoid arthritis

Computer vision tool effectively distinguishes rheumatoid arthritis from osteoarthritis in joint tissue

New HSS study clarifies the clinical manifestations of undifferentiated connective tissue disease

ASU study explores components of the immune system

Researchers show how electrical stimulation of the vagus nerve in inflammation promotes healing

After SARS-CoV-2 infection, anti-chemokine antibodies correlate with better outcomes

Olverembatinib a potent inhibitor of Omicron NTD-mediated cytokine release

Molecular profiling of diseased joints could transform treatment for rheumatoid arthritis patients

Patients, doctors, insurers agree: Prior approvals for treatment should come faster

New AI tool can speed up the diagnosis of psoriatic arthritis by up to 4 years

Enzyme discovery offers new way to regulate cell death process for inflammatory diseases

Study estimates effectiveness of 2-dose and 3-dose mRNA vaccination against Omicron

Report highlights the need for an office to support autoimmune disease research across NIH institutes

Detecting treatments for autoimmune disease using an immune ‘fingerprint’

Urgent action needed to address disparities in women’s heart health

Novel genetic mapping study traces links between DNA variations and blood proteins

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Rheumatoid Arthritis News and Research

Latest Rheumatoid Arthritis News and Research

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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