Seizure News and Research

Latest Seizure News and Research

Child's epilepsy diagnosis impacts mother's mental health and family environment

A study by Canadian researchers examined the prevalence of maternal depression and its impact on children newly diagnosed with epilepsy. Prevalence of depression in mothers ranged from 30%-38% within the first 24 months following a child's epilepsy diagnosis.

5 Jan 2011

Removal of ZIP proteins from hippocampus cell protects them from injury

Researchers in the Blue Bird Circle Developmental Neurogenetics Laboratory in the department of neurology at Baylor College of Medicine have discovered that zinc enters cells through specialized protein gates known as ZIP transporters, and removing these ZIP proteins from cells in the hippocampus significantly protects them from injury.

5 Jan 2011

General anesthesia's similarities with and differences from sleep and coma

The use of general anesthesia is a routine part of surgical operations at hospitals and medical facilities around the world, but the precise biological mechanisms that underlie anesthetic drugs' effects on the brain and the body are only beginning to be understood. A review article in the December 30 New England Journal of Medicine brings together for the first time information from a range of disciplines, including neuroscience and sleep medicine, to lay the groundwork for more comprehensive investigations of processes underlying general anesthesia.

30 Dec 2010

Merck announces FDA approval for GARDASIL against HPV-related anal cancer

Merck, known as MSD outside the United States and Canada, announced today that the U.S. Food and Drug Administration (FDA) has approved GARDASIL® [Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant] for the prevention of anal cancer caused by human papillomavirus (HPV) types 16 and 18 and for the prevention of anal intraepithelial neoplasia (AIN) grades 1, 2 and 3 (anal dysplasias and precancerous lesions) caused by HPV types 6, 11, 16 and 18, in males and females 9 through 26 years of age.

23 Dec 2010

FDA joins Abbott Diabetes Careto to recall 359 glucose test strips

The test strips being recalled may give falsely low blood glucose results. False results may lead patients to try to raise their blood glucose unnecessarily, or they may fail to treat elevated blood glucose because of a false, low reading. Both scenarios pose risks to a patient's health.

22 Dec 2010

FDA issues CRL to Cumberland's Acetadote sNDA for non-acetaminophen acute liver failure

Cumberland Pharmaceuticals Inc. announced today that it has received a Complete Response Letter from the U.S. Food and Drug Administration (FDA) regarding its supplemental new drug application (sNDA) for Acetadote® (acetylcysteine) Injection to treat patients with non-acetaminophen induced acute liver failure.

22 Dec 2010

Genentech confirms EMA, FDA updates on Avastin for metastatic breast cancer

Genentech, a member of the Roche Group, confirmed that following the reviews of Avastin® (bevacizumab) in metastatic breast cancer by the European Medicines Agency (EMA) and the U.S. Food and Drug Administration (FDA), the following regulatory announcements were made by the individual health authorities:

17 Dec 2010

Food stored at rodent-infested warehouse seized by U.S. Marshals

U.S. Marshals, acting under a court order sought by the U.S. Food and Drug Administration, today seized chili pods, ground chili, crushed chili, and other chili products located in the rodent-infested food warehouse owned by Duran and Sons LLC in Derry, New Mexico. The New Mexico Environment Department had previously placed an embargo on all products in the company's food warehouse on Nov. 17, 2010.

14 Dec 2010

Appeals Court upholds preliminary injunction against FDA to stop seizure of electronic cigarettes

In a straightforward decision, a Federal Appeals Court has upheld a preliminary injunction against the FDA to stop the seizure of the electronic cigarette as it enters the country to suppliers that retail them to the smoking public.

9 Dec 2010

New finding could help identify individuals with abnormal brain function

Mayo Clinic researchers found that the part of the brain generating seizures in individuals with epilepsy is functionally isolated from surrounding brain regions. The researchers hope this finding could be a clinical biomarker to help identify individuals with abnormal brain function.

9 Dec 2010

Sunovion reports results of Latuda third phase 3 worldwide clinical trial for schizophrenia

Sunovion Pharmaceuticals Inc. today announced the results of the PEARL 3 study, the third phase 3 worldwide clinical trial of Latuda® (lurasidone HCl) tablets, a once-daily atypical antipsychotic agent recently approved by the U.S. Food and Drug Administration (FDA) for the treatment of patients with schizophrenia. In this six-week, placebo-controlled trial, both fixed doses of LATUDA 80 and 160 mg once-daily, demonstrated statistically significant improvement in symptoms of schizophrenia versus placebo across both primary and secondary efficacy measures.

9 Dec 2010

Low-dose diazepam with NS-398 combination has twice the neuroprotective effect of NS-398 alone

Status epilepticus, prolonged seizures, can lead to significant neurological deficits and, rarely, even death. The anticonvulsant diazepam, a first line therapy for the condition, is neuroprotective when administered in high doses within two hours from seizure onset. Researchers at the 64th AES Annual Meeting now report that the combination of low-dose diazepam and NS-398, a COX-2 inhibitor, has twice the neuroprotective effect of NS-398 alone.

8 Dec 2010

AHNPs may serve as effective treatment for epilepsy and other disorders with altered neuronal circuitry

Epilepsy research is reaching beyond improving the means for quelling symptoms to the exploration of potential modalities for correcting or reversing alterations in neural function that underlay some forms of the disorder.

8 Dec 2010

Micromet announces presentation of updated results from MT103 Phase 2 trial in MRD positive ALL patients

Micromet, Inc. today announced the presentation of updated results from a Phase 2 trial of the Company's lead product candidate blinatumomab (MT103) in adult patients with minimal residual disease (MRD) positive acute lymphoblastic leukemia (ALL). An analysis of long-term efficacy data demonstrated that blinatumomab produced prolonged remissions in patients with ALL. As of November 2010, the hematologic disease free survival (DFS) was 60%, with a follow-up of up to 27.5 months.

7 Dec 2010

Long-term prognosis still excellent for children with seizures

Mayo Clinic researchers studied more than 200 children with epilepsy and found that even if the cause of focal-onset seizures cannot be identified and they do not fit into a known epilepsy syndrome, long-term prognosis is still excellent. This study was presented at the American Epilepsy Society's annual meeting in San Antonio on Dec. 4.

7 Dec 2010

Adverse birth outcomes partially explain epilepsy mortality

A higher rate of mortality is known to be associated with epilepsy, but the precise contribution of the underlying health factors is unknown. The results from the study of a large cohort of people born in Denmark in 1977 through 2006 were reported today at the American Epilepsy Society meeting here.

7 Dec 2010

Global phase III study to provide novel extended release of topiramate

Data presented yesterday showed that USL255, a novel extended-release (ER) formulation of topiramate, was associated with less fluctuation in topiramate plasma levels than immediate-release (IR) topiramate in healthy volunteers.

7 Dec 2010

Data analysis reveals significant risk factors for sudden unexpected death in epilepsy

Sudden unexpected death in epilepsy (SUDEP) is the most common condition-related cause of death in chronic epilepsy. Case-control studies using living people with epilepsy as controls have aimed at identifying factors that distinguish the epilepsy patient at risk of SUDEP, but there are disagreements between studies and a lack of precision in the risk estimates attributed, in part, to the small number of cases in each study.

7 Dec 2010

Study confirms importance of EEG as diagnostic tool in ICU

Bleeding in and around the brain (cerebral hemorrhage, including intra-cerebral hemorrhage, subdural hematoma, subarachnoid hemorrhage among other forms), from whatever cause (stroke, ruptured aneurysm, stroke, tumor, trauma, etc) can be very irritating to the electrical cells of the brain and affect how these cells transmit signals. If cells become very irritated and/or hyperactive, seizures can occur.

6 Dec 2010

Incidence of EPTS in children with TBI more than twice the rate in adults: Study

In the first study to utilize continuous EEG monitoring to define the incidence of early post traumatic seizures in children compared to published rates in adults, investigators at the University of Colorado followed pediatric patients with moderate to severe traumatic brain injury admitted to Denver Children's Hospital over a nine month period.

6 Dec 2010

Seizure News and Research

Latest Seizure News and Research

Child's epilepsy diagnosis impacts mother's mental health and family environment

Removal of ZIP proteins from hippocampus cell protects them from injury

General anesthesia's similarities with and differences from sleep and coma

Merck announces FDA approval for GARDASIL against HPV-related anal cancer

FDA joins Abbott Diabetes Careto to recall 359 glucose test strips

FDA issues CRL to Cumberland's Acetadote sNDA for non-acetaminophen acute liver failure

Genentech confirms EMA, FDA updates on Avastin for metastatic breast cancer

Food stored at rodent-infested warehouse seized by U.S. Marshals

Appeals Court upholds preliminary injunction against FDA to stop seizure of electronic cigarettes

New finding could help identify individuals with abnormal brain function

Sunovion reports results of Latuda third phase 3 worldwide clinical trial for schizophrenia

Low-dose diazepam with NS-398 combination has twice the neuroprotective effect of NS-398 alone

AHNPs may serve as effective treatment for epilepsy and other disorders with altered neuronal circuitry

Micromet announces presentation of updated results from MT103 Phase 2 trial in MRD positive ALL patients

Long-term prognosis still excellent for children with seizures

Adverse birth outcomes partially explain epilepsy mortality

Global phase III study to provide novel extended release of topiramate

Data analysis reveals significant risk factors for sudden unexpected death in epilepsy

Study confirms importance of EEG as diagnostic tool in ICU

Incidence of EPTS in children with TBI more than twice the rate in adults: Study

Everything you need to know about epilepsy eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

Seizure News and Research

Latest Seizure News and Research

Everything you need to know about epilepsy eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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