Sepsis News and Research

Latest Sepsis News and Research

Vaccines and drugs must be adapted to combat emerging SARS-CoV-2 variants, says study

A new review of the emerging variants of concern (VOCs) of the SARS-CoV-2, which has caused the COVID-19 pandemic, shows that there is a major need to constantly re-evaluate the utility of existing therapeutics and vaccines against the virus and to develop new ones.

28 Jun 2021

Scientists make AI breakthrough in neonatal intensive care

James Cook University scientists in Australia believe they have made a breakthrough in the science of keeping premature babies alive.

25 Jun 2021

Common artificial sweeteners can lead to serious health issues

New research has discovered that common artificial sweeteners can cause previously healthy gut bacteria to become diseased and invade the gut wall, potentially leading to serious health issues.

24 Jun 2021

CD39+ monocyte count higher in pregnant than non-pregnant COVID-19 patients

A new study published on the bioRxiv* server describes the changes in the representation of a subset of activated monocytes in this group of patients.

23 Jun 2021

Can convalescent plasma therapy improve COVID-19 outcomes in patients with hematologic cancers?

A recent study discusses the findings of a study on patients with hematologic cancers who received convalescent plasma therapy following their diagnosis of COVID-19.

21 Jun 2021

Which vitamins and minerals help with COVID?

A study published in the journal Inflammopharmacology reviewed recent data related to the role of vitamins and minerals in treating COVID-19 patients. The primary goal of the review is to highlight the possible therapeutic role of vitamins A, B, C, D, E and K, and micronutrients as immunity boosters in COVID-19 patients.

18 Jun 2021

Combination of anti-HER2 breast cancer therapy and checkpoint inhibitor provides no benefit

Adding an immune checkpoint inhibitor to anti-HER2 treatment in breast cancer does not improve pathological complete response (pCR), according to the primary analysis of the IMpassion050 trial presented today during the ESMO Virtual Plenary.

18 Jun 2021

Immune cell-mimicking nanoparticles deliver drugs directly to inflamed lungs

Nanoengineers at the University of California San Diego have developed immune cell-mimicking nanoparticles that target inflammation in the lungs and deliver drugs directly where they're needed. As a proof of concept, the researchers filled the nanoparticles with the drug dexamethasone and administered them to mice with inflamed lung tissue.

17 Jun 2021

Immune system dysfunction can alter the link between cannabis use and psychosis

The presence of pro-inflammatory cytokines in the blood can boost the effects of daily cannabis use and heighten the risk of developing psychosis in adulthood.

16 Jun 2021

Statins associated with reduced COVID-19 mortality and decreased need for ventilator support

Statins are medications widely used in the management of cardiovascular diseases and metabolic syndrome. Statins help lower serum lipids by blocking HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-coenzyme A reductase), the rate-limiting enzyme of cholesterol biosynthesis.

11 Jun 2021

Cross-sectional study explores differences in biomarkers in fulminant and non-fulminant COVID-19 myocarditis

Researchers from the US recently conducted a study to examine the clinical course and echocardiographic and lab testing across clinically defined fulminant and non-fulminant COVID-19 myocarditis. This study is published on the preprint server, medRxiv.*

11 Jun 2021

New cell-penetrating peptide may protect against life-threatening microbial inflammation

A cell-penetrating peptide developed by researchers at Vanderbilt University Medical Center can prevent, in an animal model, the often-fatal septic shock that can result from bacterial and viral infections.

9 Jun 2021

Pathogenic airway neutrophilia drives ARDS in Black patients with severe COVID-19 in case study

Researchers from the US used a systems immunology approach where they combined high-dimensional flow cytometry and multi-omics single-cell sequencing analyses of immune profiles taken from the airways and matching blood samples of Black/AA patients.

9 Jun 2021

Link between SARS-CoV-2 organotropism and kidney injury

It was clear at a relatively early stage of the pandemic that SARS-CoV-2 causes a wide range of symptoms; in addition to typical respiratory symptoms, patients also had neurological symptoms (starting with anosmia), gastrointestinal symptoms, elevated liver values, and renal, urinary or hematological changes, for example.

8 Jun 2021

Could a green tea compound combat SARS-CoV-2?

Researchers recently published an article that reviewed the mechanisms by which EGCG could inhibit SARS-CoV-2 infection and the various syndromes caused by COVID-19.

3 Jun 2021

Inflammatory brain injury higher in men with acute COVID-19, finds study

The COVID-19 pandemic has been associated with both short- and long-term neurologic complications, including stroke, brain fog and persistent tiredness. A new study concludes that the effects of SARS-CoV-2 on the central nervous system (CNS) are due to the endothelial injury and inflammation that this produces in the brain.

31 May 2021

Vagus nerve stimulation may be a potential adjunct therapy for COVID-19

COVID-19 was initially described as lung inflammation, or pneumonia, in older adults. However, we now know that SARS-CoV-2 infections can cause a wide range of symptoms in people of all ages, ranging from no symptoms at all to systemic inflammation and even death.

27 May 2021

Decreasing activity of ZMPSTE24 protease with age and comorbidities may make elderly COVID-19 patients vulnerable

Studies have shown that circulating levels of PAI-1, the coagulation cascade activator, are considerably higher in COVID-19 patients with severe respiratory illness compared to patients with bacterial-sepsis and acute respiratory distress syndrome (ARDS). Hence the increase in PAI-1 levels is recognized as an early marker of endothelial dysfunction in COVID-19 patients.

23 May 2021

Risk factors for rare COVID-19 complications in children (MIS-C)

While the earlier waves of COVID-19 relatively spared children, some of the affected children have developed a systemic inflammatory condition, with occasionally fatal outcomes. Called multisystem inflammatory syndrome in children (MIS-C), its pathogenesis and risk factors are the subject of a new study on the medRxiv* preprint server.

21 May 2021

Study validates predictive model for identifying pediatric patients at risk for developing blood clots

Monroe Carell Jr. Children's Hospital at Vanderbilt has launched a study to determine the impact of a predictive model for identifying pediatric patients at risk for developing blood clots or venous thromboembolisms (VTEs).

19 May 2021

Sepsis News and Research

Latest Sepsis News and Research

Vaccines and drugs must be adapted to combat emerging SARS-CoV-2 variants, says study

Scientists make AI breakthrough in neonatal intensive care

Common artificial sweeteners can lead to serious health issues

CD39+ monocyte count higher in pregnant than non-pregnant COVID-19 patients

Can convalescent plasma therapy improve COVID-19 outcomes in patients with hematologic cancers?

Which vitamins and minerals help with COVID?

Combination of anti-HER2 breast cancer therapy and checkpoint inhibitor provides no benefit

Immune cell-mimicking nanoparticles deliver drugs directly to inflamed lungs

Immune system dysfunction can alter the link between cannabis use and psychosis

Statins associated with reduced COVID-19 mortality and decreased need for ventilator support

Cross-sectional study explores differences in biomarkers in fulminant and non-fulminant COVID-19 myocarditis

New cell-penetrating peptide may protect against life-threatening microbial inflammation

Pathogenic airway neutrophilia drives ARDS in Black patients with severe COVID-19 in case study

Link between SARS-CoV-2 organotropism and kidney injury

Could a green tea compound combat SARS-CoV-2?

Inflammatory brain injury higher in men with acute COVID-19, finds study

Vagus nerve stimulation may be a potential adjunct therapy for COVID-19

Decreasing activity of ZMPSTE24 protease with age and comorbidities may make elderly COVID-19 patients vulnerable

Risk factors for rare COVID-19 complications in children (MIS-C)

Study validates predictive model for identifying pediatric patients at risk for developing blood clots

Innovation in neuroscience drug discovery - eBook eBook

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

Sepsis News and Research

Latest Sepsis News and Research

Innovation in neuroscience drug discovery - eBook eBook

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

Newsletters you may be interested in