Sepsis News and Research

Latest Sepsis News and Research

Antidepressant drug fluvoxamine may prevent some serious complications of COVID-19

In a preliminary study of COVID-19 patients with mild-to-moderate disease who were attempting to recover in their homes, researchers at Washington University School of Medicine in St. Louis have found that the drug fluvoxamine seems to prevent some of the most serious complications of the illness and make hospitalization and the need for supplemental oxygen less likely.

12 Nov 2020

Effectiveness of vitamin C against COVID-19 depends on its natural transporter levels

High doses of vitamin C under study for treating COVID-19 may benefit some populations, but investigators exploring its potential in aging say key factors in effectiveness include levels of the natural transporter needed to get the vitamin inside cells.

11 Nov 2020

Single clinical laboratory test can rapidly detect serious infections

UC San Francisco scientists have developed a single clinical laboratory test capable of zeroing in on the microbial miscreant afflicting patients hospitalized with serious infections in as little as six hour.

11 Nov 2020

ERC Synergy project explores causes of drug tolerance in intractable fungal infections

Over the next six years, research groups at Charité - Universitätsmedizin Berlin and Tel Aviv University will study how invasive fungal pathogens are able to evade treatments and develop tolerance to antifungal drugs.

10 Nov 2020

Melatonin may be a viable treatment option for COVID-19, study suggests

Results from a new Cleveland Clinic-led study suggest that melatonin, a hormone that regulates the sleep-wake cycle and is commonly used as an over-the-counter sleep aid, may be a viable treatment option for COVID-19.

9 Nov 2020

Search for a snakebite drug might lead to a COVID treatment, too

Dr. Matthew Lewin, founder of the Center for Exploration and Travel Health at the California Academy of Sciences, was researching snakebite treatments in rural locations in preparation for an expedition to the Philippines in 2011.

9 Nov 2020

Researchers develop a unique method of identifying early signs of acute kidney injury

Researchers at the University of Liverpool have identified a unique method of identifying the early signs of a potentially serious condition known as Acute Kidney Injury (AKI).

2 Nov 2020

New project aims to find the effect of COVID-19 infection on the next generation

So far, 50 Covid-19 patients between 30 and 40 have delivered a sperm sample. Students are next in line. The plan is that participants will return after 12 months for more testing.

2 Nov 2020

Ethacridine blocks SARS-CoV-2 with a distinct mode of action

Now, researchers from the University of California, San Francisco, and Stanford University, California, USA, reported a safe and potent antiseptic for use in humans named ethacridine, which effectively inhibits SARS-CoV-2 even at very low concentrations of EC50 ~ 0.08 µM. Their work has is published on the preprint server bioRxiv*.

1 Nov 2020

Penn State and Stanford University collaborate to develop two-hour sepsis test

One in three people who die in U.S. hospitals have sepsis, the body's extreme response to infection that can lead to multiple organ failure. Diagnosis can take up to five days, but death may take only hours from the initial onset of sepsis.

30 Oct 2020

Symptoms and outcomes of 3.32 million people tested for SARS-CoV-2

A recent study published on the preprint server medRxiv* in October 2020 shows the need for large-scale studies on the clinical characteristics and outcomes of COVID-19 at the national and international scale. This is essential to shape interventions and optimize the use of resources to contain and manage a second wave of the pandemic.

30 Oct 2020

DNase coated melanin-like nanospheres for sepsis treatment in severe COVID

As the treatment of severe COVID-19 is very difficult, the researchers from the Korea Research Institute of Biosciences and Biotechnology (KRIBB) suggested that DNase-1 can be utilized to dissolve the neutrophil extracellular traps (NETs), hence halting the further progression of COVID-19.

27 Oct 2020

Delaying urgent health issues can be more harmful than the potential risk of COVID-19

More than half a year into the COVID-19 (coronavirus) pandemic, healthcare providers have adapted by offering virtual visits and observing strict safety measures in clinics.

27 Oct 2020

Vitamin C and COVID-19: A Review

In a recent review published in Preprints*, Patrick Holford et al. address vitamin C's role as adjunctive therapy for respiratory infection, sepsis, and COVID-19.

23 Oct 2020

Researchers aim to identify disease tolerance mechanisms in sepsis patients

Sepsis is estimated to cause 11 million deaths every year in the world. Its treatment is based on the use of antibiotics and organ support measures, but many times it fails due to unsuccessful attempts at modulating the immune response.

16 Oct 2020

Scientists engineer powerful novel anti-microbial molecules from wasp venom

Now, a team of scientists in the Perelman School of Medicine at the University of Pennsylvania has engineered potent novel anti-microbial molecules from toxic proteins found in wasp venom. The researchers believe that the discovery holds promise in fighting the increasing number of antibiotic-resistant bacteria, that cause serious illness.

15 Oct 2020

GIV protein involved in the immune system could form basis for novel therapeutics

The immune response to infections is a delicate balance. We need just enough action to clear away the offending bacteria or viruses, but not so much that our own bodies suffer collateral damage.

15 Oct 2020

Certain live-attenuated vaccines can prevent severe complications of COVID-19

COVID-19 continues to wreak havoc globally, with over one million deaths to date. Yet what if an existing vaccine could make COVID-19 less deadly? A study just published put the theory to test, with promising results.

15 Oct 2020

Study may lead to new therapies to improve survival in septic patients

Each year, some 270,000 Americans die from sepsis, in which the release of normally helpful infection-fighting chemicals in the body triggers an unusually extreme immune response - powerful enough to cause life-threatening damage to blood vessels and organs.

15 Oct 2020

Waterbirths as safe as traditional births, study shows

A new U.S. study of waterbirths found that hospital-based births involving water immersion had no higher risk of neonatal intensive care unit (NICU) or special care nursery admission than comparable deliveries in the control group without water immersion.

14 Oct 2020