Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

New protocol for the study of SARS-CoV-2's medium and long-term outcomes

The clinical symptoms of the severe COVID-19 have been well described. In addition, scientists have defined the post-acute COVID-19 as the development of sequelae or persistence of symptoms several weeks after the onset of COVID-19 symptoms. In some cases, the symptoms persist for around 3-4 weeks, and in other cases of chronic COVID-19, symptoms may persist beyond 12 weeks from the onset of symptoms.

9 Aug 2021

Study shows impaired SARS-CoV-2 mRNA vaccine antibody response in individuals with chronic conditions

A recent study in Colorado used real-world data to evaluate if individuals with chronic conditions have reduced antibody response to COVID-19 mRNA vaccines. The study investigated whether some medical conditions may impact antibody response to the mRNA vaccines.

9 Aug 2021

Controlling the spread of SARS-CoV-2 at a large public university

Researchers from the U.S. recently reported a multimodal "SHIELD: Target, Test, and Tell" program that helped mitigate the transmission of SARS-CoV-2 at a large public university. The program also prevented community transmission and helped the continuation of in-person classes during the pandemic. This study is available on the medRxiv* preprint server.

9 Aug 2021

A multi-scale cryo-correlative platform to image SARS-CoV-2 in Vero cells

A new study describes the cytopathic episodes triggered by SARS-CoV-2 with virus replication processes in frozen-hydrated cells.

9 Aug 2021

Flavonoid-based inhibitors targeting SARS-CoV 3CL protease for the treatment of SARS-CoV-2 infection

A new study has explored a series of potential flavonoid inhibitors targeting 3CL protease of SARS-CoV.

9 Aug 2021

Expert panel recommends standardized criteria to define placental SARS-CoV-2 infection

A panel of experts convened by the National Institutes of Health has recommended standardized criteria to define infection of the placenta with SARS-CoV-2, the virus that causes COVID-19.

9 Aug 2021

Study of antibody responses to COVID-19 mRNA vaccine in convalescent individuals

In addition to clinical trials conducted to determine the safety and efficacy of the mRNA vaccines, additional studies began describing the serological response to the vaccines under "real-world" conditions, especially with the onset of the SARS-CoV-2 variants and case reports of vaccine escape.

9 Aug 2021

Research shows how SARS-CoV-2 variants are evolving towards increased furin cleavage efficiency

The spike protein comprises of two subunits: S1 subunit having the receptor-binding domain (RBD) that helps it to bind to the angiotensin-converting enzyme 2 (ACE2), which is present on the cell surface of the host, and the S2 subunit that helps in the fusion of the cellular membrane and the viral membrane.

9 Aug 2021

Scientists identify calpeptin as potential inhibitor of SARS-CoV-2

A team of US-based scientists has recently conducted a robust high-throughput screening to identify potential entry inhibitors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The screening identifies calpeptin as a potent and highly specific inhibitor of SARS-CoV-2 and its variants. The study is currently available on the bioRxiv* preprint server.

9 Aug 2021

Cetylpyridinium chloride-containing mouthwashes shown to inhibit SARS-CoV-2 in oral cavity

A team of international scientists has recently demonstrated the usefulness of cetylpyridinium chloride-containing mouthwashes in inhibiting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and reducing the risk of viral transmission. The study is currently available on the bioRxiv* preprint server.

9 Aug 2021

Computational study identifies key areas of the SARS-CoV-2 genome prone to mutation

By retrieving 329,942 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) records from the GISAID database, researchers from a software company in Cambridge described genetic variability of SARS-CoV-2 in order to inform further studies. Their findings are currently available on the bioRxiv* preprint server while it undergoes peer review.

9 Aug 2021

New insight into impact of SARS-CoV-2 mutations on receptor binding

A recent study by Canadian researchers, currently available on the bioRxiv* preprint server, contributes to the growing body of literature on emerging variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by appraising the impact of single mutations on their overall antigenicity and binding affinity for the angiotensin-converting enzyme 2 (ACE2) receptor.

9 Aug 2021

Virus-like particles reveal unexpected mechanism for increased fitness and spread of SARS-CoV-2

Researchers in the United States have developed a new model for testing mutations in the four structural proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

9 Aug 2021

New phylogenomic platform identifies increased recombination rates in SARS-CoV-2

Researchers in the United States, Australia and the UK have developed a novel method that enables the evolutionary ancestry (phylogeny) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to be comprehensively searched for recombinant lineages.

8 Aug 2021

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

New protocol for the study of SARS-CoV-2's medium and long-term outcomes

Study shows impaired SARS-CoV-2 mRNA vaccine antibody response in individuals with chronic conditions

Controlling the spread of SARS-CoV-2 at a large public university

A multi-scale cryo-correlative platform to image SARS-CoV-2 in Vero cells

Flavonoid-based inhibitors targeting SARS-CoV 3CL protease for the treatment of SARS-CoV-2 infection

Expert panel recommends standardized criteria to define placental SARS-CoV-2 infection

Study of antibody responses to COVID-19 mRNA vaccine in convalescent individuals

Research shows how SARS-CoV-2 variants are evolving towards increased furin cleavage efficiency

Scientists identify calpeptin as potential inhibitor of SARS-CoV-2

Cetylpyridinium chloride-containing mouthwashes shown to inhibit SARS-CoV-2 in oral cavity

Computational study identifies key areas of the SARS-CoV-2 genome prone to mutation

New insight into impact of SARS-CoV-2 mutations on receptor binding

Virus-like particles reveal unexpected mechanism for increased fitness and spread of SARS-CoV-2

New phylogenomic platform identifies increased recombination rates in SARS-CoV-2

High rates of COVID-19 vaccine motivation among Latinx parents – a single center study

Long COVID may be due to persistent immune disturbances

New study describes SARS-CoV-2 ExoN enzyme that promotes antiviral resistance

Pfizer/BioNTech COVID-19 vaccine offers decreased protection six months after second dose, suggests Israeli study

SARS-CoV-2 Beta variant associated with more critical and fatal disease than Alpha, suggests Qatar study

Study reports on COVID-19 vaccine-related adverse events in young Japanese population

Building Bridges to Scalable Allogeneic Cell Therapy

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Building Bridges to Scalable Allogeneic Cell Therapy

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

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