Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Monoclonal antibody-based blocking ELISA for SARS-CoV-2 detection in animals

In a recent study posted to the bioRxiv* preprint server, researchers in the United States described a blocking enzyme-linked immunosorbent assay (ELISA) to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure in animals.

16 Mar 2023

Ipsilateral vaccination improves response to second dose of COVID-19 vaccine

Researchers examine whether the involvement of the ipsilateral or contralateral lymph nodes affected the immune response during sequential vaccination.

16 Mar 2023

Research highlights the importance of ventilation and air filtration to reduce pathogen transmission

Testing of ambient air can be used to monitor the community circulation of respiratory pathogens.

16 Mar 2023

A novel pan-sarbecovirus vaccine candidate neutralizes Omicron BQ.1.1 and XBB subvariants

Researchers provide evidence that a novel vaccine candidate robustly neutralized SARS-CoV-2 Omicron subvariants BQ.1.1 and XBB.

16 Mar 2023

Is there an association between COVID-19 and an increased incidence of temporomandibular disorders?

Researchers assessed the association between COVID-19-related stress, depression, anxiety, and temporomandibular disorders from childhood to adulthood.

16 Mar 2023

Bat stem cells reveal how bats survive in a virus-filled environment

A recent Cell journal study tested the hypothesis that bats genetically induce the virus for immune evasion and provide fertile ground for replication.

15 Mar 2023

Four COVID-19 booster doses most effective way to prevent critical Omicron BA.5

A study published in JAMA Network Open explores the protective efficacy of previous exposure to omicron subvariants and booster vaccination against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) omicron BA.5 infection.

15 Mar 2023

Vaccination protects lupus patients from contracting COVID-19

Researchers determine the risk of COVID-19 and possibility of severe sequelae in patients with systemic lupus erythematosus and the general population.

14 Mar 2023

An overview of COVID-19-associated neurological complications in children

Researchers review current literature to understand the association between COVID-19, neuroimaging, and neurological symptoms in children.

14 Mar 2023

Researchers model possible COVID-19 trajectories for 2023

Researchers model predictions of the COVID-19 pandemic trajectory under different variant and intervention scenarios.

14 Mar 2023

Spike-induced humoral immunity and its association with antibody-dependent cellular cytotoxicity potency

A new study aimed to analyze the qualitative and quantitative impact of S-induced humoral immunity along with its ADCC capability in individuals who received a vaccination, recovered from an infection, or both.

14 Mar 2023

Do the symptom profiles among children with SARS-CoV-2 infection differ by variant type?

Researchers performed a comparative analysis of symptoms related to SARS-CoV-2 variants in children.

14 Mar 2023

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

Researchers investigated whether mRNA technology-based COVID-19 vaccines promote the development of autoantibodies.

14 Mar 2023

Study shows SARS-CoV-2 causes DNA damage and elicits an altered DNA damage response

Researchers assessed the association between SARS-CoV-2 infection and DNA damage and cellular senescence.

14 Mar 2023

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Researchers showed that mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) chromatin remodeling complexes represent a potential class of host-directed broad-acting SARS-CoV-2 therapeutic targets.

14 Mar 2023

Oral host responses to SARS-CoV-2 predict progression of COVID-19

In a recent study posted to the medRxiv* preprint server, researchers at the University of North Carolina and the National Institutes of Health determined the associations between oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), oral antibodies against SARS-CoV-2, and coronavirus disease 2019 (COVID-19) symptoms.

14 Mar 2023

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Researchers from The University of Texas MD Anderson Cancer Center have developed fully human bispecific antibodies, as revealed in a recent study. These antibodies can bind to two distinct epitopes of the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and have demonstrated the ability to neutralize various strains of the virus, including the Omicron variant.

14 Mar 2023