Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Gimsilumab trial starts in first US patient with ARDS and COVID-19

The first American patient with COVID-19 and acute respiratory distress syndrome (ARDS) has been put on the drug gimsilumab at Temple University Hospital, as part of the BREATHE clinical trial. The trial, sponsored by Roivant Sciences, will evaluate the effectiveness of intravenous gimsilumab in preventing death in patients with COVID-19 and ARDS.

16 Apr 2020

Random testing key to a safe exit from COVID-19 lockdown

The coronavirus disease (COVID019) global pandemic has placed many countries and regions in lockdown. There are thousands of cases reported daily, with the global infection toll topping 2.15 million. How can nations shift from lockdown back to normal daily routines while ensuring there won’t be a second wave of viral infection?

16 Apr 2020

On and off social distancing may be needed until 2022

Lockdown and social distancing measures are in place in many countries across the world, intended to stem the rapid spread of the coronavirus disease (COVID-19) global pandemic. These measures work by reducing the risk of viral transmission in communities, reducing the burden of the healthcare system in dealing with the surge of patients, overwhelming its resources and workforce. Now, experts warn that these social distancing measures may still be needed until 2022.

16 Apr 2020

Experts explain how to decontaminate N95 masks from SARS-CoV-2

Amid the coronavirus global pandemic, the world is facing a shortage of medical supplies, especially those intended to protect health workers. With the high demand for personal protective equipment (PPE), including surgical masks and N95 masks, many people are left with no choice but to try and decontaminate this equipment for extended use. Now, a new study by experts shows how N95 masks can be adequately decontaminated for further use.

16 Apr 2020

Supercomputer helps find 64 compounds as potential inhibitors of the COVID-19 protease

A new study published in Chemrxiv in April 2020 describes the identification of 64 compounds that could potentially be inhibitors of replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is causing the current COVID-19 disease pandemic. The research was carried out using a pharmacophore model of an essential viral enzyme, mining data from the Food and Drug Administration (FDA) database of conformations of approved drugs.

16 Apr 2020

Six novel coronaviruses found in bats

While the world grapples with the pandemic, which has spread to 185 countries and territories, infecting more than 2.15 million people and killing more than 143,000 people, a team of researchers at the Smithsonian's Global Health Program has found six novel coronaviruses in bats in Myanmar.

16 Apr 2020

Research shows speed of asymptomatic SARS-CoV-2 transmission in Boston homeless shelter

The coronavirus disease (COVID-19) is straining healthcare resources across the globe, prompting countries to impose social distancing measures to reduce the transmission of the virus. The problem is, the virus can spread even if the infected person has no symptoms, making contact tracing and isolation measures more difficult. Now, a new study reveals the rapidity of asymptomatic SARS-CoV-2 transmission that occurred in a Boston homeless shelter.

16 Apr 2020

Pregnancy and fetal outcomes with COVID-19

A new study published preprint in the non-peer-reviewed journal medRxiv in April 2020 provides a systematic review of maternal and fetal outcomes in pregnancy affected by COVID-19, as well as the risk of vertical transmission of the virus.

16 Apr 2020

Gold-containing drug auranofin kills 95% of SARS-CoV-2 virus in 48 hours in lab conditions

A drug called auranofin, approved for the treatment of rheumatoid arthritis, effectively inhibits severe acute respiratory syndrome coronavirus (SARS-CoV-2) in laboratory conditions, as described in a new study by Georgia State University researchers.

16 Apr 2020

Screening blood samples for COVID-19 using artificial intelligence

A promising new study published in the preprint online journal medRxiv in April 2020 shows the potential of artificial intelligence (AI) for developing a patient classifier that can separate patients likely to be negative for COVID-19 from among a pool of suspected patients visiting an emergency room (ER).

15 Apr 2020

Remdesivir drug stops novel coronavirus from replicating

Scientists from the University of Alberta have published findings that the antiviral drug remdesivir prevents replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by inhibiting RNA replication. The study, published in April 2020 in the Journal of Biological Chemistry, follows on the heels of earlier reports from the same lab in February, showing the drug's effectiveness against the related Middle East Respiratory Syndrome (MERS) virus.

15 Apr 2020

Anosmia (loss of smell) confirmed as a clinical feature of COVID-19

Earlier last month, the association of ear, nose, and throat (ENT) specialists in the UK issued a public statement advising patients with a sudden loss of smell or taste to get tested for COVID-19. They cited not only their own observations but those from numerous other ENT consultants the world around. A review of multiple papers on the sinus and nasal symptoms and signs related to the diagnosis of COVID-19, published in April 2020, in the journal Laryngoscope Investigative Otolaryngology, reiterates this finding.

15 Apr 2020

Coronavirus able to survive near boiling point of water, study shows

A startling paper by a team of French scientists published in the preprint journal bioRxiv in April 2020 suggests that the novel coronavirus is capable of surviving at high temperatures. This could mean that laboratory technicians handling the virus are at danger of infection.

15 Apr 2020

New coronavirus possibly circulated within humans before COVID-19 pandemic

Genetic variation analysis and the evidence of recombination events point towards the conclusion that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might have circulated cryptically among humans for years, as reported by a recent paper on a preprint server bioRxiv.

15 Apr 2020

ACE2 genetic variants may influence coronavirus disease progression

Researchers in British Columbia have identified a set of gene variants that are likely to influence disease progression from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to COVID-19 disease.

15 Apr 2020

Novel coronavirus can be airborne for 13 feet

The novel coronavirus can travel up to 13 feet or 4 meters from patients in hospital wards, a new study has found. This is twice the distance current guidelines recommend for social distancing.

14 Apr 2020

The race is on for a coronavirus vaccine, 70 candidates, 3 at human trial stage

Amid the coronavirus disease (COVID-19) global pandemic that is infecting millions of people across the globe, hope sparks as the World Health Organization (WHO) reports that seventy vaccination trials for the novel coronavirus are underway, with three already at the human trial stage.

14 Apr 2020

UK collaborates with Google, Apple on contact tracing App

The UK Health Secretary Matt Hancock recently announced that the UK government’s National Health Service (NHS) is planning to release an app that will alert people who have been in the proximity of a self-reported symptomatic individual – via anonymous phone-to-phone alerts.

14 Apr 2020

Coronavirus misinformation and disinformation rife among Americans

A new poll carried out by the Pew Research Center from March 10 to March 16, 2020, shows that almost 1 in 3 Americans think the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), that causes the current COVID-19 pandemic is the product of biological research. Despite the utter lack of evidence, the claim has found fertile breeding grounds on the Internet. It serves as an apt example of the spread of dubious or patently false information about the pandemic.

14 Apr 2020

New blood test for antibodies in COVID-19 infected

The COVID-19 disease pandemic is raging across the world, costing tens of thousands of lives. Many countries have enforced widespread, if not universal lockdowns, to prevent the spread of the virus to new areas, carried by infected travelers.

14 Apr 2020