Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Spike protein mutations in Omicron subvariants increase their susceptibility to reductive cleavage of disulfide bonds

Researchers discovered that the spike protein of SARS-CoV-2 is susceptible to cleavage at the disulfide bonds, and the vulnerability to reductive cleavage varies across variants, with the Omicron variant family being highly susceptible to reduction.

10 Jan 2023

Study explores incidence, severity, and long COVID associations of SARS-CoV-2 reinfections

Researchers used electronic health records to characterize the incidence, biomarkers, attributes, and severity of SARS-CoV-2 reinfections and evaluated the association between reinfections and long coronavirus disease (COVID).

10 Jan 2023

Researchers review bacteriophage treatment

Researchers presented an overview of bacteriophage treatment, including mechanisms, types, design and applications of bacteriophage therapy.

10 Jan 2023

Profound immune escape by SARS-CoV-2 XBB.1 even after 4 vaccine doses

In a recent correspondence published in The Lancet Infectious Diseases journal, researchers in Germany assessed the neutralization sensitivity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) XBB.1 lineage.

9 Jan 2023

Study suggests that long-COVID is associated with physical inactivity

In a recent study published in the Scientific Reports journal, researchers in Brazil assessed the association between post-acute sequelae of coronavirus disease 2019 (COVID-19) (PASC) and physical inactivity.

9 Jan 2023

Deletions in the antigenic regions in SARS-CoV-2 increase transmission and immune evasion ability

A recent study published in the journal Scientific Reports examined the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) whole genome data to determine the deletion mutations around the spike protein region associated with increased transmission of the virus and identified an increase in the deletion-prone spike protein regions indicating an evolution strategy for immune escape.

9 Jan 2023

Researchers study the spatial distribution of SARS-CoV-2 Omicron BA.1 variant in England

Researchers performed a genomic assessment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant’s BA.1 subvariant transmission in England.

9 Jan 2023

Researchers analyze targets of human T cell recognition against all coronaviruses

Researchers analyzed T cell reactivity against alpha and beta common cold coronaviruses (CoVs) [(CCC)] to inform the development of pan-CoV vaccine concepts.

9 Jan 2023

Incidence rates and characteristics associated with medically attended COVID-19 episodes among infants younger than 6 months

A recent study estimated the overall incidence rates of medically attended SARS-CoV-2 infection among infants.

9 Jan 2023

What was the prevalence of respiratory syncytial virus between August and December 2022?

Researchers presented the initial respiratory syncytial virus (RSV) surveillance findings for the period between August and December 2022.

9 Jan 2023

What is the long-term cognitive impact of COVID-19, and what are its predictors?

Scientists have described demographic and clinical predictors of cognitive dysfunction and self-perceived cognitive difficulties in COVID-19 survivors one-year after infection.

9 Jan 2023

Study reveals poor immunity against SARS-CoV-2 BQ.1.1 and XBB mutants in Norway

Researchers conducted a seroprevalence study in the general population of Norway, evaluating immunity against multiple subvariants of SARS-CoV-2 Omicron, including XBB and BQ.1.1 mutants.

9 Jan 2023

Research suggests people on rheumatoid arthritis drugs show weaker response to SARS-CoV-2 vaccines

Researchers conducted a comparative study among a cohort of individuals on rheumatoid arthritis (RA) therapies vis-à-vis healthy controls to assess their responses to coronavirus disease 2019 (COVID-19) vaccines.

9 Jan 2023

Is universal coronavirus immunity possible?

In a recent study posted to the bioRxiv* preprint server, researchers at Columbia University characterized reciprocal and non-reciprocal T-cell responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

8 Jan 2023

New research on nirmatrelvir resistance in SARS-CoV-2 using powerful replicon cell culture systems

In a recent study posted to the bioRxiv* preprint server, researchers at Emory University used severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Washington (WA.1) and Omicron (BA.1) strains to test for mutations that could result in resistance to the antiviral drug nirmatrelvir.

8 Jan 2023

COVID-19 vaccine potency and breadth improved by nanoparticle-conjugated adjuvants

In a recent study posted to bioRxiv*, researchers designed a nanoparticle (NP)-conjugated toll-like receptor 9 (TLR9) agonist to improve the adjuvanticity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines.

8 Jan 2023

Does the duration between SARS-CoV-2 infection and vaccination affect immunity?

In a recent study posted to the medRxiv* preprint server, researchers at Oregon Health & Science University assessed the impact of the duration between coronavirus disease 2019 (COVID-19) infection and vaccination on immunity against infection.

8 Jan 2023

New model for detecting and estimating pathogen variant dynamics and risk

A recent study posted to the medRxiv* preprint server developed a hierarchical modeling method to estimate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant fitness advantage and prevalence.

8 Jan 2023

Study suggests COVID-19 can cause diabetes

The authors of a new study under review at Nature Portfolio and currently posted to the Research Square preprint* server showed the clinical possibility that the coronavirus disease 2019 (COVID-19) heightens the risk of developing diabetes mellitus (DM), supporting diabetes screening in those infected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

8 Jan 2023

Does the immunization order of vaccine types influence the efficacy of heterologous prime-boost vaccination, especially mRNA and protein-based vaccines?

A new study aimed to analyze whether the order of immunization of vaccine types impacted the efficacy of a heterologous prime-boost vaccination strategy.

6 Jan 2023

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Spike protein mutations in Omicron subvariants increase their susceptibility to reductive cleavage of disulfide bonds

Study explores incidence, severity, and long COVID associations of SARS-CoV-2 reinfections

Researchers review bacteriophage treatment

Profound immune escape by SARS-CoV-2 XBB.1 even after 4 vaccine doses

Study suggests that long-COVID is associated with physical inactivity

Deletions in the antigenic regions in SARS-CoV-2 increase transmission and immune evasion ability

Researchers study the spatial distribution of SARS-CoV-2 Omicron BA.1 variant in England

Researchers analyze targets of human T cell recognition against all coronaviruses

Incidence rates and characteristics associated with medically attended COVID-19 episodes among infants younger than 6 months

What was the prevalence of respiratory syncytial virus between August and December 2022?

What is the long-term cognitive impact of COVID-19, and what are its predictors?

Study reveals poor immunity against SARS-CoV-2 BQ.1.1 and XBB mutants in Norway

Research suggests people on rheumatoid arthritis drugs show weaker response to SARS-CoV-2 vaccines

Is universal coronavirus immunity possible?

New research on nirmatrelvir resistance in SARS-CoV-2 using powerful replicon cell culture systems

COVID-19 vaccine potency and breadth improved by nanoparticle-conjugated adjuvants

Does the duration between SARS-CoV-2 infection and vaccination affect immunity?

New model for detecting and estimating pathogen variant dynamics and risk

Study suggests COVID-19 can cause diabetes

Does the immunization order of vaccine types influence the efficacy of heterologous prime-boost vaccination, especially mRNA and protein-based vaccines?

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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