Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

Researchers at Boston University made a chimeric recombinant SARS-CoV-2 encoding the spike glycoprotein gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate.

22 Oct 2022

The public health impact of the SARS-CoV-2 Omicron subvariant BA.5 relative to BA.2 in Denmark

Researchers conducted a nationwide study in Denmark to assess the public health impact of the SARS-CoV-2 Omicron subvariant BA.5 relative to BA.2.

22 Oct 2022

Exploring SARS-CoV-2-associated endothelial dysfunction

A new study described the evidence, mechanisms, and therapies for endothelial dysfunction in coronavirus disease 2019 (COVID-19).

21 Oct 2022

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

In a recent study published in the journal Nature Cell Biology, researchers demonstrated the susceptibility of salivary glands to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in vitro using an organoid culture model.

20 Oct 2022

Analgesic use after COVID-19 vaccination does not negatively affect antibody responses

In a recent study posted to the medRxiv* preprint server, University of Arizona researchers assessed the relationship between antibody responses and analgesic usage after coronavirus disease 2019 (COVID-19) vaccination.

20 Oct 2022

Multiomics analysis identifies immunobiomarkers for COVID-19 severity in outpatients

In a recent study published in the journal eLife, researchers showed the utility of machine-learning models in identifying early immune signatures, which could reliably predict clinical and immunological outcomes in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-infected outpatients.

20 Oct 2022

Are pediatric COVID-19 samples less infectious?

Researchers determine whether children are less hospitable to SARS-CoV-2 and, as a result, pose a lower risk of a viral spread than adults.

20 Oct 2022

Breakthrough infection risk and immune responses to vaccines associated with human leukocyte antigen alleles

Researchers from the U.K. used data from clinical trials of the Oxford-AstraZeneca COVID-19 vaccine ChAdOx1 nCoV-19 to understand the genetic factors contributing to the individual variations in the antibody responses to the vaccine.

20 Oct 2022

Investigating increased healthcare usage after SARS-CoV-2 infection

In a new study, researchers evaluated the post-acute burden of healthcare use after SARS-CoV-2 infection in adults.

20 Oct 2022

11 key measures for monitoring clinical activity during COVID-19

In a recent study posted to the medRxiv* preprint server, researchers in the United Kingdom described key measurements for monitoring clinical activity during the coronavirus disease 2019 (COVID-19) pandemic.

20 Oct 2022

Research uncovers mechanisms governing SARS-CoV-2 Omicron subvariant entry

In a recent study posted to the bioRxiv* preprint server, researchers at Ohio State University and the University of Texas Medical Branch assessed the underlying mechanisms involved in the fusogenicity and endosomal entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants.

20 Oct 2022

Study shows low risk of myocarditis/pericarditis after mRNA COVID-19 vaccination

Scientists determine the risk of myocarditis and pericarditis among young individuals who have received mRNA-based COVID-19 vaccines.

19 Oct 2022

Impaired SARS-CoV-2 neutralization after booster vaccination in the elderly

A recent study investigates poorer vaccine responses observed in the elderly following receipt of a COVID-19 booster vaccination dose.

19 Oct 2022

Licorice root extract shows potential as a COVID-19 treatment

A recent study explores the activity of glycyrrhizin against SARS-CoV-2.

19 Oct 2022

SARS-CoV-2 transmission from infected owner to pet rats

SARS-CoV-2 Omicron transmission from a symptomatically infected individual to two domestic rats.

19 Oct 2022

Pathophysiological mechanisms of COVID-19-related endothelial dysfunction and potential therapies

Researchers discussed the pathophysiological mechanisms of endothelial dysfunction associated with severe coronavirus disease 2019 (COVID-19) and commented on the potential therapeutic strategies to treat endothelial damage and coagulopathy related to COVID-19.

19 Oct 2022

Exploring epigenetic modifications and the use of vitamin D therapy in COVID-19

Researchers examined the role of epigenetic modifications of the host cell gene expression in determining the pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and explored the use of vitamin D as a therapeutic agent against coronavirus disease 2019 (COVID-19).

19 Oct 2022

What is the risk of severe COVID-19 in infants younger than three months?

Researchers from Italy investigated the severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in infants younger than three months and compared the reported coronavirus disease 2019 (COVID-19) severity scores for the pediatric population.

19 Oct 2022

Differential effects of SARS-CoV-2 variants on children and adolescents

A recent Emerging Infectious Diseases journal study evaluated whether specific SARS-CoV-2 variants were linked with different clinical manifestations in children and adolescents.

19 Oct 2022

Rapid and robust pipeline for developing mRNA vaccines for future SARS-CoV-2 variants

A recent study under review at the journal Scientific Reports and currently available on the Research Square* preprint server reported the development of a robust pipeline for fabricating an mRNA vaccine portfolio to combat current and future coronavirus outbreaks, other infectious diseases, and cancer.

19 Oct 2022

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

The public health impact of the SARS-CoV-2 Omicron subvariant BA.5 relative to BA.2 in Denmark

Exploring SARS-CoV-2-associated endothelial dysfunction

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

Analgesic use after COVID-19 vaccination does not negatively affect antibody responses

Multiomics analysis identifies immunobiomarkers for COVID-19 severity in outpatients

Are pediatric COVID-19 samples less infectious?

Breakthrough infection risk and immune responses to vaccines associated with human leukocyte antigen alleles

Investigating increased healthcare usage after SARS-CoV-2 infection

11 key measures for monitoring clinical activity during COVID-19

Research uncovers mechanisms governing SARS-CoV-2 Omicron subvariant entry

Study shows low risk of myocarditis/pericarditis after mRNA COVID-19 vaccination

Impaired SARS-CoV-2 neutralization after booster vaccination in the elderly

Licorice root extract shows potential as a COVID-19 treatment

SARS-CoV-2 transmission from infected owner to pet rats

Pathophysiological mechanisms of COVID-19-related endothelial dysfunction and potential therapies

Exploring epigenetic modifications and the use of vitamin D therapy in COVID-19

What is the risk of severe COVID-19 in infants younger than three months?

Differential effects of SARS-CoV-2 variants on children and adolescents

Rapid and robust pipeline for developing mRNA vaccines for future SARS-CoV-2 variants

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

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