T Cell News and Research

Latest T Cell News and Research

Innovative mouse model could provide new strategy to arrest growth of pancreatic cancer

Pancreatic ductal adenocarcinoma, the most common of pancreatic cancers, is extraordinarily lethal, with a 5-year survival rate of just 6 percent. Chemotherapy treatments are poorly effective, in part due to a high degree of drug-resistance to currently used regimens.

7 Jun 2016

Researchers establish new method to culture kidney progenitor cells for regenerative medicine

Research into kidney regeneration, an organ that has been extremely difficult to regenerate, has taken a great stride forward with research coming out of a collaboration between Kumamoto University, Japan and the National Cancer Institute of the US.

7 Jun 2016

Northwestern Medicine scientists link TMEM230 gene mutations to Parkinson's disease development

Northwestern Medicine scientists have discovered a new cause of Parkinson's disease -- mutations in a gene called TMEM230. This appears to be the third gene definitively linked to confirmed cases of the common movement disorder.

7 Jun 2016

Antiinflammatory drug HUMIRA enhances specific TNF function in rheumatoid arthritis patients

Researchers from University College London have discovered that the widely used antiinflammatory drug HUMIRA doesn't just work by inhibiting its target protein, TNF, but by enhancing a particular function of TNF in rheumatoid arthritis patients.

7 Jun 2016

Researchers aim to find new approach to improve chronic wound repair

Chronic wounds cause nearly 80,000 lower leg amputations annually in the U.S. alone and are associated with an increased likelihood of death.

6 Jun 2016

Zika virus directly infects brain progenitor cells in newborns to cause neurological problems

The mosquito-borne Zika virus linked to microcephaly and other neurological problems in newborns of affected mothers directly infects the brain progenitor cells destined to become neurons, UT Southwestern Medical Center researchers report in a study published online today in Cell Reports.

6 Jun 2016

Improved research tool may open door to effective HIV vaccine designs

Vaccines are usually medicine's best defense against the world's deadliest microbes. However, HIV is so mutable that it has so far effectively evaded both the human immune system and scientists' attempts to make an effective vaccine to protect against it.

6 Jun 2016

Research shows IFITM3 protein can block Zika virus from infecting human, mouse cells

Eight weeks after receiving their first samples of Zika virus, scientists at the University of Massachusetts Medical School have shown that a very small protein we all have in our bodies, interferon-induced protein 3 (IFITM3), can dramatically reduce the ability of Zika virus to infect human and mouse cells.

6 Jun 2016

IQWiG examines whether ramucirumab drug offers added benefit for MCRC and NSCLC patients

Ramucirumab is a monoclonal antibody, which blocks a receptor, reducing the growth of blood vessels and so reducing blood supply to the tumours.

6 Jun 2016

Study offers more insights into how sensory experiences shape brain development

Most people encounter most things by sensing them in multiple ways. As we hear the words people speak, we also see their lips move. We smell, see and hear the onions as we chop them -- and we feel them with teary eyes.

6 Jun 2016

New study finds alternative approaches to target proteins sustaining cancer, Alzheimer's disease

Drugs to treat cancer and Alzheimer's disease usually target the active sites of specific protein molecules sustaining the disease. Traditional drug design views proteins as rigid 3-D objects with active sites consisting of surface-accessible "pockets" with a specific, well-defined structure.

6 Jun 2016

Metformin along with chemotherapy/radiation improves outcomes in head and neck cancer patients

Researchers at the University of Cincinnati College of Medicine have found that adding increasing doses of an approved Type 2 diabetes drug, metformin, to a chemotherapy and radiation treatment regimen in head and neck cancer patients is not well tolerated if escalated too quickly, but allowing slower escalation could be beneficial.

6 Jun 2016

Joint research reveals key mechanisms of persistent latent infection of HTLV-1

Joint research between scientists from Kumamoto University, Japan and Imperial College London, UK has revealed the mechanisms of persistent latent infection of the human T-cell leukemia virus type 1 (HTLV-1).

6 Jun 2016

Radiation therapy with bevacizumab/pembrolizumab improves outcomes in glioma patients

Patients with recurrent high-grade glioma brain tumors have few effective treatment options and the majority of available therapies do not improve survival. Moffitt Cancer Center will present preliminary results from a phase 1 study testing whether the addition of pembrolizumab to radiation therapy and bevacizumab is safe and can control tumor growth for these patients.

6 Jun 2016

Gene dysregulation makes immune therapies less effective against metastatic melanoma

Patients who don't respond to treatments that use their own immune cells to destroy tumors, called tumor infiltrating lymphocytes, share changes in mechanisms that switch genes on or off in those cells, according to study results presented at the annual meeting of the American Society for Clinical Oncology on June 4 in Chicago.

6 Jun 2016

Novel treatment combination helps combat hard-to-treat pediatric neuroblastoma

For seven months, three-year-old Emil Abbasov underwent chemotherapy to fight the tangerine-sized, cancerous tumor growing in his abdomen. But each time, the tumor resisted harder. Each time, he felt more side effects.

6 Jun 2016

Combination therapy equally good at treating small cell lung cancer

HAVING radiotherapy once a day for six and a half weeks or twice a day for three weeks -- when combined with chemotherapy -- is equally good at treating small cell lung cancer that hasn't spread.

6 Jun 2016

Study finds increased risk of mortality in black, Hispanic cancer patients

Hispanic white and non-Hispanic black cancer patients between ages 15 and 29 may be more likely than same-aged white patients to die of their disease, according to a University of Colorado Cancer Center study presented at the American Society for Clinical Oncology Annual Meeting 2016.

6 Jun 2016

Maintenance lenalidomide treatment improves overall survival in multiple myeloma patients

While several clinical trials have demonstrated that maintenance therapy with lenalidomide reduces the risk of disease progression in patients with multiple myeloma, there have been no definitive results regarding overall survival.

6 Jun 2016

Gene alterations in WNT pathway may increase CRC risk in younger patients

While increased screening continues to drive down overall colorectal cancer rates, the rate of colorectal cancer in patients under age 50 is increasing, and the disease is commonly more aggressive in these young patients.

6 Jun 2016

T Cell News and Research

Latest T Cell News and Research

Innovative mouse model could provide new strategy to arrest growth of pancreatic cancer

Researchers establish new method to culture kidney progenitor cells for regenerative medicine

Northwestern Medicine scientists link TMEM230 gene mutations to Parkinson's disease development

Antiinflammatory drug HUMIRA enhances specific TNF function in rheumatoid arthritis patients

Researchers aim to find new approach to improve chronic wound repair

Zika virus directly infects brain progenitor cells in newborns to cause neurological problems

Improved research tool may open door to effective HIV vaccine designs

Research shows IFITM3 protein can block Zika virus from infecting human, mouse cells

IQWiG examines whether ramucirumab drug offers added benefit for MCRC and NSCLC patients

Study offers more insights into how sensory experiences shape brain development

New study finds alternative approaches to target proteins sustaining cancer, Alzheimer's disease

Metformin along with chemotherapy/radiation improves outcomes in head and neck cancer patients

Joint research reveals key mechanisms of persistent latent infection of HTLV-1

Radiation therapy with bevacizumab/pembrolizumab improves outcomes in glioma patients

Gene dysregulation makes immune therapies less effective against metastatic melanoma

Novel treatment combination helps combat hard-to-treat pediatric neuroblastoma

Combination therapy equally good at treating small cell lung cancer

Study finds increased risk of mortality in black, Hispanic cancer patients

Maintenance lenalidomide treatment improves overall survival in multiple myeloma patients

Gene alterations in WNT pathway may increase CRC risk in younger patients

Immunology eBook

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

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