T Cell News and Research

Latest T Cell News and Research

Vismodegib drug shows no addded benefit in advanced or symptomatic metastatic BCC patients

Vismodegib (trade name: Erivedge) has already been approved since 2013 for the treatment of patients with locally advanced basal cell carcinoma (BCC) or symptomatic metastatic BCC and has already undergone an early benefit assessment according to the Act on the Reform of the Market for Medicinal Products.

28 May 2016

New player in calcium signalling pathways acts as molecular brake to Orai activation

Information flow in cells relies on calcium as a key agent in several signalling pathways. Calcium dependent signalling is crucial in nearly every aspect of life - muscle movement, immune reactions, nerve function, light sensing and many such processes.

28 May 2016

Scientists discover how Zika virus replicates in the placenta

Zika virus can infect and replicate in immune cells from the placenta, without killing them, scientists have discovered. The finding may explain how the virus can pass through the placenta of a pregnant woman, on its way to infect developing brain cells in her fetus.

28 May 2016

Applying deep neural networks to predict pharmacologic properties of drugs and drug repurposing

Deep learning, frequently referred to as artificial intelligence, a branch of machine learning utilizing multiple layers of neurons to model high-level abstractions in data, has outperformed humans in tasks including image, text and voice recognition, autonomous driving and others, and is now being applied to drug discovery and biomarker development.

28 May 2016

Researchers develop new drugs for melanoma

Finding new, more effective and personalised treatments for cancer is the challenge of many researchers. A challenge that has been successfully met by a team from Inserm led by Stéphane Rocchi, which has just synthesised and developed new drugs for melanoma.

28 May 2016

Study identifies potential new treatment for subset of gastric cancer patients

Testing cancers for 'addiction' to a gene that boosts cell growth can pick out patients who may respond to a targeted drug under development, a major new study reports.

28 May 2016

Researchers discover ANKRD55 gene linked to multiple sclerosis

The Ikerbasque researcher Koen Vandenbroeck, who heads the Neurogenomiks laboratory which reports to the Achucarro centre and the UPV/EHU-University of the Basque Country, together with other national and international groups, has shown that a genetic variant in the 5q11 chromosome, which is associated with susceptibility to developing multiple sclerosis, greatly regulates a gene known as ANKRD55. ANKRD55 is a gene with an unknown function.

28 May 2016

Increasing specific microRNA levels can restore chemotherapy sensitivity in pancreatic cancer cells

By increasing the level of a specific microRNA (miRNA) molecule, researchers have for the first time restored chemotherapy sensitivity in vitro to a line of human pancreatic cancer cells that had developed resistance to a common treatment drug.

27 May 2016

New understanding of neurotransmitter transporter mechanism gives hope for treating depression, addicition

When nerve cells have to communicate with each other in our brains, it involves release of small signal molecules, the so-called neurotransmitters, which act as chemical messengers in specific points of contact between nerve cells, called synapses.

27 May 2016

Cell phone radiation exposure may lead to increased rates of rare cancers

According to new report from Microwave News, the U.S. National Toxicology Program has found increased rates of rare cancers of the heart and brain in animals exposed to cell phone radiation in a long-awaited multi-million dollar two-year study.

27 May 2016

Salk scientists discover REV-ERBα protein that controls strength of circadian rhythm

At noon every day, levels of genes and proteins throughout your body are drastically different than they are at midnight. Disruptions to this 24-hour cycle of physiological activity are why jet lag or a bad night's sleep can alter your appetite and sleep patterns for days--and even contribute to conditions like heart disease, sleep disorders and cancers.

27 May 2016

Research sheds light on how subtle genetic differences in DMD patients produce variation in symptoms

Johns Hopkins researchers report they have inadvertently found a way to make human muscle cells bearing genetic mutations from people with Duchenne muscular dystrophy (DMD).

27 May 2016

Electronic media use may affect parent-child communication

It happens in many households. Kids are tapping on their cell phones or are preoccupied by their favorite TV show as their parents ask them a question or want them to do a chore.

27 May 2016

Novel way of directly activating Bak protein can trigger cell death

Melbourne researchers have discovered a new way of triggering cell death, in a finding that could lead to drugs to treat cancer and autoimmune disease.

27 May 2016

Metabolic characteristics of CRPC may open new avenues for treatment

Advanced prostate cancer is usually treated by removing androgen, the male hormone that helps it grow. Although initially effective, this treatment often leads to the tumor becoming castration resistant- a lethal condition.

27 May 2016

Rockefeller scientists develop new technique that captures detailed snapshot of brain activity

When it comes to measuring brain activity, scientists have tools that can take a precise look at a small slice of the brain (less than one cubic millimeter), or a blurred look at a larger area.

27 May 2016

Novel method for designing geometric structures created from DNA

Among the valuable holdings in London's Wellcome Library is a rough pencil sketch made in 1953 by Francis Crick. The drawing is one of the first to show the double-helix structure of DNA--Nature's blueprint for the design of sea snails, human beings, and every other living form on earth.

27 May 2016

Drexel scientists identify how two new antimalarial drugs work

Drexel University scientists have discovered an unusual mechanism for how two new antimalarial drugs operate: They give the parasite's skin a boost in cholesterol, making it unable to traverse the narrow labyrinths of the human bloodstream.

27 May 2016

TSRI study shows how specific gene mutation promotes growth of aggressive tumors

Scientists at The Scripps Research Institute have caught a cancer-causing mutation in the act. A new study shows how a gene mutation found in several human cancers, including leukemia, gliomas and melanoma, promotes the growth of aggressive tumors.

27 May 2016

Adolescents and young adults have lower cancer survival rates compared to children

More young people of all ages are surviving cancer than ever before, but new research published today in The Lancet Oncology journal shows that adolescents and young adults have a lower chance of surviving eight relatively common types of cancer than children, according to the latest data from a long-running study of cancer survival across Europe.

27 May 2016

T Cell News and Research

Latest T Cell News and Research

Vismodegib drug shows no addded benefit in advanced or symptomatic metastatic BCC patients

New player in calcium signalling pathways acts as molecular brake to Orai activation

Scientists discover how Zika virus replicates in the placenta

Applying deep neural networks to predict pharmacologic properties of drugs and drug repurposing

Researchers develop new drugs for melanoma

Study identifies potential new treatment for subset of gastric cancer patients

Researchers discover ANKRD55 gene linked to multiple sclerosis

Increasing specific microRNA levels can restore chemotherapy sensitivity in pancreatic cancer cells

New understanding of neurotransmitter transporter mechanism gives hope for treating depression, addicition

Cell phone radiation exposure may lead to increased rates of rare cancers

Salk scientists discover REV-ERBα protein that controls strength of circadian rhythm

Research sheds light on how subtle genetic differences in DMD patients produce variation in symptoms

Electronic media use may affect parent-child communication

Novel way of directly activating Bak protein can trigger cell death

Metabolic characteristics of CRPC may open new avenues for treatment

Rockefeller scientists develop new technique that captures detailed snapshot of brain activity

Novel method for designing geometric structures created from DNA

Drexel scientists identify how two new antimalarial drugs work

TSRI study shows how specific gene mutation promotes growth of aggressive tumors

Adolescents and young adults have lower cancer survival rates compared to children

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

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