T Cell News and Research

Latest T Cell News and Research

Researchers uncover new mechanism that p53 protein uses to trigger cell death

Researchers have identified a new mechanism that the tumor suppressor protein p53 uses to trigger cell death via apoptosis and have shown how the process could be harnessed to kill cancer cells. St. Jude Children's Research Hospital scientists led the study, which appears today in the scientific journal Molecular Cell.

31 Jul 2015

Scientists produce functional liver cells from human embryonic and genetic engineered stem cells

The liver plays a critical role in human metabolism. As the gatekeeper of the digestive track, this massive organ is responsible for drug breakdown and is therefore the first to be injured due to overdose or misuse. Evaluating this drug-induced liver injury is a critical part of pharmaceutical drug discovery and must be carried out on human liver cells. Regretfully, human liver cells, called hepatocytes, are in scarce supply as they can only be isolated from donated organs.

31 Jul 2015

DNA study reveals potential treatments to delay or prevent onset of Huntington's disease

Scientists from Cardiff University believe that a treatment to prevent or delay the symptoms of Huntington’s disease could now be much closer, following a major breakthrough.

31 Jul 2015

New blood test could help diagnose severity of traumatic brain injury

A new blood test could help emergency room doctors quickly diagnose traumatic brain injury and determine its severity.

31 Jul 2015

Daiichi Sankyo, Plexxikon’s Phase 1 trial shows PLX3397 induced prolonged tumor regression in TGCT patients

Daiichi Sankyo Europe and Plexxikon Inc., a member of the Daiichi Sankyo Group, announced today that The New England Journal of Medicine published clinical trial results demonstrating that the investigational drug, PLX3397, an oral targeted CSF-1R inhibitor, induced prolonged tumor regressions in most patients with tenosynovial giant cell tumor, a rare, locally aggressive neoplasm of the joint or tendon sheath.

31 Jul 2015

Researchers uncover master regulators that govern the fate of TFH cells

Follicular helper Tcells (TFH cells), a rare type of immune cell that is essential for inducing a strong and lasting antibody response to viruses and other microbes, have garnered intense interest in recent years but the molecular signals that drive their differentiation had remained unclear.

31 Jul 2015

New Penn study questions relevance of fish oil-derived SPMs and their anti-inflammatory effects in humans

The importance of a diet rich in fish oils - now a billion dollar food-supplement industry -- has been debated for over half a century. A few large clinical trials have supported the idea that fish oils confer therapeutic benefits to patients with cardiovascular disease. Researchers think that hearts and blood vessels may benefit in part from their anti-inflammatory properties.

31 Jul 2015

Prostate cancer discovery may improve treatment strategies

Scientists from Cancer Research UK have discovered that there are five different types of prostate cancer and have found a way of distinguishing between them. These findings could change how the condition is treated, providing more effective therapies where they are needed the most.

30 Jul 2015

Cryoport to offer cryogenic logistics solutions to HemaCare

Cryoport, Inc., the leading provider of advanced cryogenic logistics solutions for the life sciences industry, serving markets including immunotherapies, stem cells, cell lines, clinical research organizations, vaccine manufacturers, animal health, and reproductive medicine, today announced that the Company will provide cryogenic logistics solutions to HemaCare Corporation, a leading global provider of high-quality biological material to the scientific community.

30 Jul 2015

Intracellular microlasers may allow accurate measurement of small changes occurring within cells

Massachusetts General Hospital (MGH) investigators have induced structures incorporated within individual cells to produce laser light.

30 Jul 2015

Roche submits cobas EGFR v2 test PMA to FDA as companion diagnostic test for AZD9291

Roche today announced it has submitted the cobas EGFR Mutation Test v2 for Premarket Approval (PMA) to the U.S. Food and Drug Administration, as a companion diagnostic test for AZD9291, an AstraZeneca investigational therapy for non-small cell lung cancer patients with an acquired resistant mutation.

30 Jul 2015

Study sheds light on certain antagonist drugs that block physiological responses

Members of the Consolidated Research Group of Molecular Neurobiology of the Department of Biochemistry and Molecular Biology of the University of Barcelona (UB), affiliated with the Centre for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED), have published a study in the journal Proceedings of the National Academy of Sciences (PNAS) about the formation of G protein-coupled receptors (GPCRs) which allows understanding the unexpected behaviour of some antagonists that block physiological responses.

30 Jul 2015

Balancing cellular aging and cancer risk through biotechnology

In a way, trying to repair age-related heart damage and trying to fight cancer are opposite problems. Your heart cells' ability to regenerate themselves and proliferate into new, young cells degrades as you get older.

30 Jul 2015

Intraoperative fluorescent imaging detects lung adenocarcinoma during pulmonary resection

More than 80,000 people undergo resection of a pulmonary tumor each year, and currently the only method to determine if the tumor is malignant is histologic analysis. A new study reports that a targeted molecular contrast agent can be used successfully to cause lung adenocarcinomas to fluoresce during pulmonary surgery.

30 Jul 2015

Study on marine snails could help better understand underlying mechanisms of age-related memory loss

A new research study on marine snails uncovered the first cells in the nervous system to fail during aging. The University of Miami Rosenstiel School of Marine and Atmospheric Science researchers' findings are important to better understanding the underlying mechanisms of age-related memory loss in humans.

30 Jul 2015

New research shows promising progress in use of anti-inflammatory cytokine for T1D treatment

New research from Uppsala University shows promising progress in the use of anti-inflammatory cytokine for treatment of type 1 diabetes. The study, published in the open access journal Scientific Reports (Nature Publishing Group), reveals that administration of interleukin-35 (a protein made by immune cells) to mice with type 1 diabetes, reverses or cures the disease by maintaining a normal blood glucose level and the immune tolerance.

30 Jul 2015

Detailed molecular analyses reveal new treatment options for aggressive childhood leukemia

Acute lymphoblastic leukemia (ALL) leukemia is the most common type of cancer in children. It can occur in various forms, differing not only by specific changes in the genetic material of the leukemia cells but also by their response to therapies. Now, an international team of scientists from Berlin, Düsseldorf, Hannover, Heidelberg, Kiel, and Zurich have succeeded in decoding the molecular characteristics of an as yet incurable subtype of leukemia, paving the way for new therapeutic approaches.

30 Jul 2015

Patients undergoing surgery for lung cancer wait too long to receive treatment, skip vital diagnostic steps

Patients undergoing surgery for lung cancer may wait too long to receive treatment, and too many patients skip vital diagnostic steps that are needed to help determine the best possible treatment, according to an article in the August 2015 issue of The Annals of Thoracic Surgery.

30 Jul 2015

New study reports creation of genetic porcine model of cancer

With many types of cancers, early detection offers the best hope for survival. However, research into new early-detection screenings, as well as possible interventional radiology and surgical treatments, has been hindered by the lack of a large animal model that would accurately reflect the types of cancers seen in human cells.

30 Jul 2015

One sunburn increases risk of skin cancer by 50%

Everybody's got a story about that "one bad burn" - the time you fell asleep next to the pool and tattooed a white handprint on your lobster-red chest, or forgot to pack the sunscreen while hiking a Colorado 14er.

30 Jul 2015

T Cell News and Research

Latest T Cell News and Research

Researchers uncover new mechanism that p53 protein uses to trigger cell death

Scientists produce functional liver cells from human embryonic and genetic engineered stem cells

DNA study reveals potential treatments to delay or prevent onset of Huntington's disease

New blood test could help diagnose severity of traumatic brain injury

Daiichi Sankyo, Plexxikon’s Phase 1 trial shows PLX3397 induced prolonged tumor regression in TGCT patients

Researchers uncover master regulators that govern the fate of TFH cells

New Penn study questions relevance of fish oil-derived SPMs and their anti-inflammatory effects in humans

Prostate cancer discovery may improve treatment strategies

Cryoport to offer cryogenic logistics solutions to HemaCare

Intracellular microlasers may allow accurate measurement of small changes occurring within cells

Roche submits cobas EGFR v2 test PMA to FDA as companion diagnostic test for AZD9291

Study sheds light on certain antagonist drugs that block physiological responses

Balancing cellular aging and cancer risk through biotechnology

Intraoperative fluorescent imaging detects lung adenocarcinoma during pulmonary resection

Study on marine snails could help better understand underlying mechanisms of age-related memory loss

New research shows promising progress in use of anti-inflammatory cytokine for T1D treatment

Detailed molecular analyses reveal new treatment options for aggressive childhood leukemia

Patients undergoing surgery for lung cancer wait too long to receive treatment, skip vital diagnostic steps

New study reports creation of genetic porcine model of cancer

One sunburn increases risk of skin cancer by 50%

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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