T Cell News and Research

Latest T Cell News and Research

New drug shows promise in driving insulin-producing beta cells to multiply

In a screen of more than 100,000 potential drugs, only one, harmine, drove human insulin-producing beta cells to multiply, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai, funded by JDRF and the National Institutes of Health, and published online today in Nature Medicine.

10 Mar 2015

United Therapeutics announces FDA approval of dinutuximab for treatment of high-risk neuroblastoma

United Therapeutics Corporation announced today that the United States Food and Drug Administration has approved Unituxin (dinutuximab) Injection (formerly called ch14.18), in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-2 (IL-2), and 13-cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk neuroblastoma who achieve at least a partial response to prior first-line multiagent, multimodality therapy.

10 Mar 2015

NMR screening solution specifically for the analysis of honey launched by Bruker

This new NMR screening solution specifically for the analysis of honey is the most recent module of Bruker’s well-established FoodScreener™ product line to be released in April.

From Bruker 10 Mar 2015

Wine-Profiling solution based on NMR introduced by Bruker

This substantially enhanced second-generation module of the FoodScreener™ for wine profiling allows easy and cost-efficient NMR-based wine analysis, now for the first time also for key regions in France, Italy and Spain. In addition to geographical origin, NMR Wine Profiling can determine further key authenticity parameters such as grape variety, vintage year and possible water addition. This comprehensive solution offers a quick, fully automated and cost-efficient tool to ensure wine quality and authenticity, protecting brand integrity and consumer confidence.

From Bruker 10 Mar 2015

Salk scientists move one step closer to creating drug that could prevent HIV virus

Imagine a single drug that could prevent human immunodeficiency virus (HIV) infection, treat patients who have already contracted HIV, and even remove all the dormant copies of the virus from those with the more advanced disease. It sounds like science fiction, but Salk scientists have gotten one step closer to creating such a drug by customizing a powerful defense system used by many bacteria and training this scissor-like machinery to recognize the HIV virus.

10 Mar 2015

Researchers identify new class of drugs that slows aging process

A research team from The Scripps Research Institute, Mayo Clinic and other institutions has identified a new class of drugs that in animal models dramatically slows the aging process—alleviating symptoms of frailty, improving cardiac function and extending a healthy lifespan.

10 Mar 2015

Finding appears to support the hypothesis that Alzheimer's is an autoimmune disease

Brain levels of the lipid ceramide are high in Alzheimer's disease, and now scientists have found increased levels of an antibody to the lipid in their disease model.

10 Mar 2015

Viagra can have anti-cancer, anti-Alzheimer's disease effects if used with new drugs

Chaperone proteins play an important role in protein folding in human cells and in bacteria and are promising new targets for drugs to treat cancer and Alzheimer's disease and for novel antiviral drugs and antibiotics. How existing drugs such as Viagra or Cialis and a derivative of the drug Celebrex, for example, can reduce the activity of a specific chaperone protein, with the potential for anti-tumor and anti-Alzheimer's disease effects, is described in a Review article in DNA and Cell Biology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

10 Mar 2015

Imperial scientists develop new test that uses human stem cells to predict side effects of drugs

Scientists at Imperial College London have developed a test that uses combinations of cells from a single donor's blood to predict whether a new drug will cause a severe immune reaction in humans.

10 Mar 2015

Researchers take images of tiny molecular machine that bacteria use to infect host cells

Armed with a microscope capable of zooming in on organisms measured in billionths of a meter, scientists report they are the first to observe one of the tiny molecular machines that bacteria use to infect host cells. Findings appear in the Proceedings of the National Academy of Sciences.

10 Mar 2015

Researchers use stem cells from sickle cell disease patients to grow mature red blood cells

Researchers at Johns Hopkins have successfully corrected a genetic error in stem cells from patients with sickle cell disease, and then used those cells to grow mature red blood cells, they report. The study represents an important step toward more effectively treating certain patients with sickle cell disease who need frequent blood transfusions and currently have few options.

10 Mar 2015

Scientists find blood-based genomic biomarkers that could help identify young boys with ASD

In a study published in the current online issue of JAMA Psychiatry, an international team of scientists, led by researchers at the University of California, San Diego School of Medicine, report finding a highly accurate blood-based measure that could lead to development of a clinical test for autism spectrum disorder (ASD) risk in males as young as one to two years old.

10 Mar 2015

Understanding genetic machinery that drives malignant pediatric adrenocortical tumors

In an advance that could lead to better identification of malignant pediatric adrenocortical tumors, and ultimately to better treatment, researchers have mapped the "genomic landscape" of these rare childhood tumors. Their genomic mapping has revealed unprecedented details, not only of the aberrant genetic and chromosomal changes that drive the cancer, but the sequence of those changes that trigger it.

10 Mar 2015

UC Irvine researchers discover inner mechanisms of jet lag

Long the stuff of science fiction, the disembodied "brain in a jar" is providing science fact for UC Irvine researchers, who by studying the whole brains of fruit flies are discovering the inner mechanisms of jet lag.

10 Mar 2015

Researchers locate, narrow down genes that play role in Type 1 diabetes

The genes that increase the risk of Type 1 diabetes have lost their hiding place.

10 Mar 2015

UTSA professor named Gold Fellow of the Association for Research in Vision and Ophthamology

Andrew Tsin, professor of biology in the UTSA College of Sciences, has been named a Gold Fellow of the Association for Research in Vision and Ophthamology for his dedication and exemplary contributions in the field. Tsin will receive the honor at the 2015 ARVO Annual Meeting, May 3-7 in Denver.

10 Mar 2015

Blood group O provides protection against severe malaria

It has long been known that people with blood type O are protected from dying of severe malaria. In a study published in Nature Medicine, a team of Scandinavian scientists explains the mechanisms behind the protection that blood type O provides, and suggest that the selective pressure imposed by malaria may contribute to the variable global distribution of ABO blood groups in the human population.

10 Mar 2015

Snai1 protein plays major role in deciding fate of intestinal stem cells

An international group of researchers has shown that a regulatory protein involved in controlling how cancer spreads through the body also influences the fate of stem cells in the intestine of mice. The results, which are published in The EMBO Journal, show that the Snai1 protein plays an important role in deciding the fate of intestinal stem cells and the different functions that these cells can adopt.

10 Mar 2015

Advanced Cell Diagnostics' RNAscope technology supports biomarker-selected phase 2 clinical trial of Merrimack Pharmaceuticals' MM-121

Advanced Cell Diagnostics, Inc. (ACD) announced today that Merrimack Pharmaceuticals, Inc. is using ACD's RNAscope technology to select patients for its Phase 2 clinical trial of its product candidate MM-121.

From Advanced Cell Diagnostics 9 Mar 2015

The Brain Prize awarded to four scientists for development of two-photon microscopy

The world's most valuable (€1m) neuroscience prize, The Brain Prize has been awarded, to four scientists, Winfried Denk and Arthur Konnerth (Germany), and Karel Svoboda and David Tank (USA), for the invention and development of two-photon microscopy, a transformative tool in brain research.

9 Mar 2015

T Cell News and Research

Latest T Cell News and Research

New drug shows promise in driving insulin-producing beta cells to multiply

United Therapeutics announces FDA approval of dinutuximab for treatment of high-risk neuroblastoma

NMR screening solution specifically for the analysis of honey launched by Bruker

Wine-Profiling solution based on NMR introduced by Bruker

Salk scientists move one step closer to creating drug that could prevent HIV virus

Researchers identify new class of drugs that slows aging process

Finding appears to support the hypothesis that Alzheimer's is an autoimmune disease

Viagra can have anti-cancer, anti-Alzheimer's disease effects if used with new drugs

Imperial scientists develop new test that uses human stem cells to predict side effects of drugs

Researchers take images of tiny molecular machine that bacteria use to infect host cells

Researchers use stem cells from sickle cell disease patients to grow mature red blood cells

Scientists find blood-based genomic biomarkers that could help identify young boys with ASD

Understanding genetic machinery that drives malignant pediatric adrenocortical tumors

UC Irvine researchers discover inner mechanisms of jet lag

Researchers locate, narrow down genes that play role in Type 1 diabetes

UTSA professor named Gold Fellow of the Association for Research in Vision and Ophthamology

Blood group O provides protection against severe malaria

Snai1 protein plays major role in deciding fate of intestinal stem cells

Advanced Cell Diagnostics' RNAscope technology supports biomarker-selected phase 2 clinical trial of Merrimack Pharmaceuticals' MM-121

The Brain Prize awarded to four scientists for development of two-photon microscopy

Immunology eBook

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

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