T Cell News and Research

Latest T Cell News and Research

Could nanoparticle vaccines offer broad protection against sarbecoviruses?

To understand the ability of SARS-CoV-2 vaccine-elicited antibodies to neutralize and protect against emerging variants (that are pathogenic) and other sarbecoviruses, a large team of researchers studied immunity by receptor-binding domain nanoparticle vaccines. They showed that a clinical-stage multivalent SARS-CoV-2 receptor-binding domain nanoparticle vaccine (SARS-CoV-2 RBD-NP) protected mice from the SARS-CoV-2-induced disease.

22 Mar 2021

Novel technology may reveal the brain's mysteries

A team of scientists, led by researchers at Northwestern University, Shirley Ryan AbilityLab and the University of Illinois at Chicago (UIC), has developed novel technology promising to increase understanding of how brains develop, and offer answers on repairing brains in the wake of neurotrauma and neurodegenerative diseases.

22 Mar 2021

New study to identify prenatal and early childhood markers of high risk for food allergy and eczema

A study to identify prenatal and early childhood markers of high risk for food allergy and atopic dermatitis, or eczema, as well as biological pathways that lead to these conditions, has begun.

22 Mar 2021

First model of early human embryo generated from skin cells

In a discovery that will revolutionise research into the causes of early miscarriage, infertility and the study of early human development - an international team of scientists led by Monash University in Melbourne, Australia has generated a model of a human embryo from skin cells.

22 Mar 2021

New study shows how the immune system relates to cancer

Three University of Colorado Cancer Center researchers are part of a team that recently published a paper offering new insight into how the immune system relates to cancer.

22 Mar 2021

New book explains the functional aspects of melanogenesis and related disorders

The Vertebrate Pigmentary System: From pigment cells to disorders provides readers with fundamental knowledge of the structural and functional aspects of vertebrate pigment cells - melanophores and melanocytes - from their origin to different stages of development to related diseases.

22 Mar 2021

Clofazimine inhibits coronaviruses including SARS-CoV-2, study finds

Researchers at the University of Hong Kong found that Clofazimine, a lipophilic antimicrobial riminophenazine dye used in combination with agents like rifampicin and dapsone to treat leprosy, inhibits coronaviruses, including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19 disease.

21 Mar 2021

Blocking folate metabolism could reduce SARS-CoV-2 viral replication in infected cells

The novel beta-coronavirus virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and coronaviruses, in general, alter the host's cellular metabolism to support massive production of ~30 kB viral genomes and subgenomic viral RNAs. However, how this is achieved is largely unknown.

21 Mar 2021

Circular RNA vaccine shows neutralizing activity against B.1.351 variant

New preclinical research led by Wensheng Wei from Peking University in China has proposed the development of a circular RNA vaccine. Their findings showed the circular RNA vaccine creates neutralizing antibodies and strong T-cell responses against the receptor-binding domain of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.

21 Mar 2021

Acute exposure of lung tissue to vape aerosol has lesser impact on gene expression than cigarette smoke

A new peer-reviewed study published in the journal Toxicological Research & Application shows acute exposure of a 3D human bronchial tissue model to e-cigarette aerosol has minimal impact on gene expression compared to smoke from combustible cigarettes.

21 Mar 2021

Study maps structure and mechanism of a membrane enzyme that plays role in inflammation, cancer

Most drugs operate via the membranes that surround the body's cells. A study by researchers at Karolinska Institutet in Sweden has now mapped the structure and mechanism of MGST2, a membrane enzyme that, amongst other things, plays a part in chronic inflammation and cancer.

20 Mar 2021

New cellular device with computing capacity could be used outside the laboratory

The Research Group on Synthetic Biology for Biomedical Applications at Pompeu Fabra University in Barcelona, Spain, has designed a cellular device capable of computing by printing cells on paper. For the first time, they have developed a living device that could be used outside the laboratory without a specialist, and it could be produced on an industrial scale at low cost.

20 Mar 2021

Researchers describe a new approach to treating Parkinson's disease

Parkinson's disease is the second most common, age-related, neurodegenerative disease: In Germany alone, about 300,000 people are affected and experience sometimes major limitations to their quality of life.

20 Mar 2021

Newly discovered enzyme on deadly fungus may be the key to fight fungal infection

Aspergillus fumigatus kills as many people as malaria and tuberculosis, but is less known. It is found "everywhere", for example in the soil or in our compost, but is not normally dangerous to healthy people.

20 Mar 2021

$11 million COBRE funding will help create Center for Pre-Clinical Cancer Research at LSU SVM

The Louisiana State University School of Veterinary Medicine, or LSU SVM, has received an $11 million grant to establish a Center of Biomedical Research Excellence, or COBRE.

19 Mar 2021

VHIO-born spin-off receives approval to initiate Phase I/II clinical trial of novel Myc inhibitor

Co-founded back in 2014 by VHIO's Laura Soucek, CEO of the enterprise, and Marie-Eve Beaulieu, Chief Scientific Officer (CSO) of the company, VHIO-born spin-off Peptomyc S.L. has just announced that it has received approval from the Spanish Agency of Medicines and Medical Devices for conducting clinical trials in Spain (AEMPS), to initiate the first-in-human Phase I/II clinical trial with its first compound - a disruptive Myc inhibitor, Omomyc (OMO-103).

19 Mar 2021

T Cell News and Research

Latest T Cell News and Research

Could nanoparticle vaccines offer broad protection against sarbecoviruses?

Novel technology may reveal the brain's mysteries

New study to identify prenatal and early childhood markers of high risk for food allergy and eczema

First model of early human embryo generated from skin cells

New study shows how the immune system relates to cancer

New book explains the functional aspects of melanogenesis and related disorders

Clofazimine inhibits coronaviruses including SARS-CoV-2, study finds

Blocking folate metabolism could reduce SARS-CoV-2 viral replication in infected cells

Circular RNA vaccine shows neutralizing activity against B.1.351 variant

Acute exposure of lung tissue to vape aerosol has lesser impact on gene expression than cigarette smoke

Study maps structure and mechanism of a membrane enzyme that plays role in inflammation, cancer

New cellular device with computing capacity could be used outside the laboratory

Researchers describe a new approach to treating Parkinson's disease

Newly discovered enzyme on deadly fungus may be the key to fight fungal infection

$11 million COBRE funding will help create Center for Pre-Clinical Cancer Research at LSU SVM

VHIO-born spin-off receives approval to initiate Phase I/II clinical trial of novel Myc inhibitor

Underrepresentation in genomic databases may affect therapy selection for minority patients

New approach to cancer immunotherapy may prevent autoimmunity

Researchers unveil a neuroprotective pathway that suppresses ALS

Developing a COVID-19 vaccine using inactivated E. coli

Immunology eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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