T Cell News and Research

Latest T Cell News and Research

Molecular modeling helps identify the binding site of antidepressantss

The effects of selective serotonin reuptake inhibitors (SSRIs) and other conventional antidepressants are believed to be based on their increasing the levels of serotonin and noradrenalin in synapses, while ketamine, a new rapid-acting antidepressant, is thought to function by inhibiting receptors for the neurotransmitter glutamate.

19 Feb 2021

An optimized process to isolate and purify magnetic nanoparticles

Magnetic nanoparticles biosynthesized by bacteria might soon play an important role in biomedicine and biotechnology. Researchers of the University of Bayreuth have now developed and optimized a process for the isolation and purification of these particles from bacterial cells.

19 Feb 2021

Trispecific antibody targets cancer cells, natural killer cells

Several treatments for cancer have been devised by science, but unfortunately none of them are completely efficient or foolproof.

19 Feb 2021

Researchers develop new tool to decipher cellular conversations

An interdisciplinary team of biologists and mathematicians at the University of California, Irvine has developed a new tool to help decipher the language cells use to communicate with one another.

18 Feb 2021

Specific cell-to-cell communication associated with progression of gastrointestinal stromal tumors

Gastrointestinal stromal tumors (GISTs) are a subytpe of cancers known as sarcomas. GIST is the most common type of sarcoma with approximately 5,000 to 6,000 new patient cases annually in the United States.

18 Feb 2021

Immune response to SARS-CoV-2 may be limited by a set of genes

Neutralizing antibodies develop within two weeks of a SARS-CoV-2 infection, but their durability and intensity can vary by individual, prompting concerns about the prospects of long-lasting immunity and efficacy of COVID-19 vaccines.

18 Feb 2021

Combination therapy produces clinical benefit for early stage non-small cell lung cancer

The first randomized Phase II clinical trial to report on single and combined neoadjuvant immune checkpoint inhibitor therapy in stage I-III non-small cell lung cancer (NSCLC) found combination therapy produced a significant clinical benefit, as assessed by major pathologic response (MPR) rate, as well as enhanced tumor immune cell infiltration and immunological memory.

18 Feb 2021

O-glycosylation of SARS-CoV-2 spike protein in insect and human cell lines

The mapping of O-glycosites requires instruments that can support electron transfer dissociation (ETD) fragmentation. In a new study published on the bioRxiv preprint server, researchers report their results on whether O-glycosylation patterns affect immunogens for vaccine development.

18 Feb 2021

Polycomb complexes found to be essential for proper skin development

Mount Sinai researchers have discovered that Polycomb complexes, groups of proteins that maintain gene expression patterns, are essential for proper skin development, according to a paper published in Genes & Development on February 18.

18 Feb 2021

Could measles virus vectors be used for a new COVID-19 vaccine?

A research team at the Institut Pasteur in France describes the successful development of such a vaccine utilizing a measles virus vector.

18 Feb 2021

Researchers discover potential new way to target pancreatic tumors with high IFN signaling

UCLA Jonsson Comprehensive Cancer Center researchers have uncovered a potential new way to target pancreatic tumors that express high intratumoral interferon signaling (IFN).

18 Feb 2021

UC San Diego researchers launch clinical trial to test gene therapy for Alzheimer’s disease

Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia.

18 Feb 2021

Study provides new insight into the effects of antidepressant drugs

18 Feb 2021

Early immunosuppressive biomarkers could predict bone regeneration after trauma

An abnormal suppression of the immune system linked to the onset of numerous diseases has been associated with poor functional regeneration of traumatic bone injuries.

18 Feb 2021

Study reveals extremely low detection of SARS-CoV-2 on surfaces in oncology facilities

Researchers from Rutgers Cancer Institute of New Jersey, the state's only National Cancer Institute-designated Comprehensive Cancer Center, evaluated the frequency of SARS-CoV-2, the virus that causes COVID-19, on various environmental surfaces in outpatient and inpatient hematology/oncology settings located within Rutgers Cancer Institute and Robert Wood Johnson University Hospital, an RWJBarnabas Health facility.

18 Feb 2021

Biophysicists show how cancer cells become fluidized and squeeze through tissues

Working with colleagues from Germany and the US, researchers at Leipzig University have achieved a breakthrough in research into how cancer cells spread.

18 Feb 2021

Researchers use high-resolution imaging to observe HIV infection process in the cell nucleus

Scientists at EMBL Heidelberg and at the Zentrum für Infektiologie at Heidelberg University Hospital have succeeded for the first time in imaging HIV during transport into the nucleus of an infected cell.

18 Feb 2021

Biomedical engineer receives NASA grant to find ways to keep astronauts' bones strong in space

Extended time in space weakens astronauts' bones, so scientists are working to better understand how bone senses and responds to the usual forces placed upon it with the goal of keeping their bones strong.

18 Feb 2021

Analyzing short strands of cell-free DNA in urine could help detect early-stage cancer

Urinalysis has long been a staple of physical exams to detect and manage a number of diseases and disorders, but not cancer.

18 Feb 2021

Clinical trial shows five-year outcomes of CAR T-cell therapy for non-Hodgkin lymphomas

A significant number of non-Hodgkin lymphoma (NHL) patients in a Penn Medicine-initiated clinical trial continue to be in remission five years after receiving the chimeric antigen receptor (CAR) T cell therapy Kymriah, researchers in Penn's Abramson Cancer Center reported today in the New England Journal of Medicine.

18 Feb 2021

T Cell News and Research

Latest T Cell News and Research

Molecular modeling helps identify the binding site of antidepressantss

An optimized process to isolate and purify magnetic nanoparticles

Trispecific antibody targets cancer cells, natural killer cells

Researchers develop new tool to decipher cellular conversations

Specific cell-to-cell communication associated with progression of gastrointestinal stromal tumors

Immune response to SARS-CoV-2 may be limited by a set of genes

Combination therapy produces clinical benefit for early stage non-small cell lung cancer

O-glycosylation of SARS-CoV-2 spike protein in insect and human cell lines

Polycomb complexes found to be essential for proper skin development

Could measles virus vectors be used for a new COVID-19 vaccine?

Researchers discover potential new way to target pancreatic tumors with high IFN signaling

UC San Diego researchers launch clinical trial to test gene therapy for Alzheimer’s disease

Study provides new insight into the effects of antidepressant drugs

Early immunosuppressive biomarkers could predict bone regeneration after trauma

Study reveals extremely low detection of SARS-CoV-2 on surfaces in oncology facilities

Biophysicists show how cancer cells become fluidized and squeeze through tissues

Researchers use high-resolution imaging to observe HIV infection process in the cell nucleus

Biomedical engineer receives NASA grant to find ways to keep astronauts' bones strong in space

Analyzing short strands of cell-free DNA in urine could help detect early-stage cancer

Clinical trial shows five-year outcomes of CAR T-cell therapy for non-Hodgkin lymphomas

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

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