T Cell News and Research

Latest T Cell News and Research

Alpaca nanobodies neutralize SARS-CoV-2 in vitro

A new preprint research paper posted to the bioRxiv server reports the development of highly effective neutralizing nanobodies targeting the viral receptor-binding domain (RBD), thus disrupting its engagement with the host cell angiotensin-converting enzyme 2 (ACE2) receptor.

4 Feb 2021

SHREK proteins mediate broad spectrum antiviral host immunity, including against SARS-CoV-2

A new preprint posted to the bioRxiv server demonstrates that similar mucins and mucin-like proteins cannot only suppress HIV-1 infectivity via blockage of viral attachment to the host cells but can block infection by multiple enveloped viruses.

4 Feb 2021

SARS-CoV-2 N501Y mutation adversely affects cellular immune response

Among these is the B.1.1.7 SARS-CoV-2 variant, with its characteristic N501Y mutation. A new preprint on the bioRxiv server reports the impact of this mutation on CD4 T cell responses, including antigen presentation on cells expressing Major Histocompatibility Complex (MHC) class II molecules.

4 Feb 2021

Imaging SARS-CoV-2 with a helium ion microscope for the first time

Scientists at Bielefeld University's Faculty of Physics have succeeded for the first time in imaging the SARS-CoV-2 coronavirus with a helium ion microscope.

4 Feb 2021

Emory MVA COVID-19 vaccine proven safe and effective in mice and monkeys

Researchers at Yerkes National Primate Research Center, Emory University, have developed a COVID-19 vaccine that has proven safe and effective in mice and monkeys.

4 Feb 2021

ZyCoV-D SARS-CoV-2 DNA vaccine shows robust immunogenicity and protective efficacy in Rhesus macaquesys

A team of scientists from India has recently tested the efficacy and immunogenicity of two different concentrations of a plasmid DNA-based vaccine candidate ZyCoV-D. The findings reveal that the vaccine candidate administered via Needle Free Injection System (NFIS) can significantly induce the production of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein-specific IgG and neutralizing antibodies for a prolonged period.

4 Feb 2021

Novel biomarker may help identify which pancreatic cancer patients respond to CD40 agonists

Inflammation in the blood could serve as a new biomarker to help identify patients with advanced pancreatic cancer who won't respond to the immune-stimulating drugs known as CD40 agonists, suggests a new study from researchers in the Abramson Cancer Center of the University of Pennsylvania published in JCI Insight.

4 Feb 2021

New combination therapy proven to be highly effective in HBV infection model

Around 260 million people, more than three percent of the global population, are chronically infected with the hepatitis B virus (HBV); in the long term, this often leads to complications such as liver cirrhosis and liver cancer.

4 Feb 2021

Scientists identify genomic signatures of long-term survival in luminal breast cancer patients

Researchers at NUI Galway have identified genomic signatures in women developing the most common type of breast cancer that can be associated with long-term survival.

4 Feb 2021

POSTECH researchers discover mechanism behind intestinal epithelial lymphocyte differentiation

The intestine harbors the largest number of immune cells in our body. Since the intestine is constantly exposed to various antigens like bacteria and food, appropriate induction of gut immune cells plays a pivotal role in gut homeostasis.

4 Feb 2021

virusPHIX™ virus inactivation medium launched by RNAssist & Rapid Labs Ltd.

RNAssist (Cambridge UK) and Rapid Labs Ltd (Colchester, UK) have launched the virusPHIX™ range of virus inactivating and RNA stabilising transport media, following successful SARS-CoV-2 inactivation testing carried out by Public Health England (PHE).

From Rapid Labs Ltd 4 Feb 2021

Researchers develop thermostable RNA vaccine delivery platform

A new study describes the production of a new RNA vaccine delivery system that promises greater ease of storage and distribution. This could help boost vaccination rates in regions without adequate infrastructure for low-temperature storage.

4 Feb 2021

Alzheimer's risk gene can increase COVID-19 susceptibility and severity

A City of Hope-led research team found that the same gene that increases the risk for Alzheimer's disease, ApoE4, can increase the susceptibility to and severity of COVID-19.

4 Feb 2021

Gut microbiome can modulate the immune response in liver cancer patients with NAFLD

The distinctive gut microbiome profile of a person with liver cancer linked to non-alcoholic fatty liver disease (NAFLD) could be the key to predicting someone's risk of developing the cancer, say researchers from the UNSW Microbiome Research Centre.

4 Feb 2021

South African SARS-CoV-2 variant neutralized by two Chinese vaccines in case study

A new study offers some reassuring findings, reporting the successful neutralization of the South African SARS-CoV-2 variant of concern (VOC) 501Y.V2 by two vaccines developed in China.

4 Feb 2021

Pfizer vaccine and Eli Lilly monoclonal antibodies successfully neutralize SARS-CoV-2 UK variant, finds study

A new study reports the underlying basis of increased transmissibility in the N501Y UK variant and provides reassuring data on the efficacy of the Pfizer vaccine and Eli Lilly monoclonal antibodies in neutralizing it.

4 Feb 2021

Monoclonal antibodies against SARS-CoV-2 spike's N-terminal prove highly protective in vivo

A new study server reports highly protective neutralizing monoclonal antibodies against the SARS-CoV-2.

4 Feb 2021

Researchers develop prototype COVID-19 vaccine using DNA vaccine platform

It is necessary to develop additional COVID-19 vaccines, as different vaccine approaches have their advantages and disadvantages and may work synergistically.

4 Feb 2021

REGENHU announces its participation in the FLAMIN-GO project aimed at developing "personalized" treatments against rheumatoid arthritis

REGENHU announced its participation in the FLAMIN-GO research project aimed at developing an organ-on-chip technology for clinical trials on Rheumatoid Arthritis.

From regenHU Ltd. 4 Feb 2021

Study shows that human hormones also follow a seasonal pattern

Our minds may be affected by winter's long nights or spring's flowers, but what about our bodies? A new study at the Weizmann Institute of Science reveals that our hormones also follow a seasonal pattern.

4 Feb 2021

T Cell News and Research

Latest T Cell News and Research

Alpaca nanobodies neutralize SARS-CoV-2 in vitro

SHREK proteins mediate broad spectrum antiviral host immunity, including against SARS-CoV-2

SARS-CoV-2 N501Y mutation adversely affects cellular immune response

Imaging SARS-CoV-2 with a helium ion microscope for the first time

Emory MVA COVID-19 vaccine proven safe and effective in mice and monkeys

ZyCoV-D SARS-CoV-2 DNA vaccine shows robust immunogenicity and protective efficacy in Rhesus macaquesys

Novel biomarker may help identify which pancreatic cancer patients respond to CD40 agonists

New combination therapy proven to be highly effective in HBV infection model

Scientists identify genomic signatures of long-term survival in luminal breast cancer patients

POSTECH researchers discover mechanism behind intestinal epithelial lymphocyte differentiation

virusPHIX™ virus inactivation medium launched by RNAssist & Rapid Labs Ltd.

Researchers develop thermostable RNA vaccine delivery platform

Alzheimer's risk gene can increase COVID-19 susceptibility and severity

Gut microbiome can modulate the immune response in liver cancer patients with NAFLD

South African SARS-CoV-2 variant neutralized by two Chinese vaccines in case study

Pfizer vaccine and Eli Lilly monoclonal antibodies successfully neutralize SARS-CoV-2 UK variant, finds study

Monoclonal antibodies against SARS-CoV-2 spike's N-terminal prove highly protective in vivo

Researchers develop prototype COVID-19 vaccine using DNA vaccine platform

REGENHU announces its participation in the FLAMIN-GO project aimed at developing "personalized" treatments against rheumatoid arthritis

Study shows that human hormones also follow a seasonal pattern

Immunology eBook

Transforming Lab Workflows with Cell Culture Automation

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Edoardo Fabini

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

Edoardo Fabini

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