T Cell News and Research

Latest T Cell News and Research

Gene expression patterns in cancer could aid early screening and prevention

Distinctive patterns of genes turned off - or left on - in healthy versus cancerous cells could enable early screening for many common cancers and maybe help avoid them, Medical College of Georgia scientists say.

28 Jul 2009

Deferoxamine could help diabetics heal wounds

A drug used to remove iron from the body could help doctors fight one of diabetes' cruelest complications: poor wound healing, which can lead to amputation of patients' toes, feet and even legs.

28 Jul 2009

Cost effectiveness study looks at potential value of new genetic test for guiding chemotherapy treatment

For the 29,000 patients in the United States with metastatic colorectal cancer, chemotherapy with irinotecan is a standard treatment that has been shown to improve survival. But for more than one in 10 of these patients, a variation in their DNA means that this treatment could result in a severe reduction in their white blood cell count, leading to a high risk of bacterial infection and possible subsequent death.

27 Jul 2009

New clues about the roots of neurological disease

Switching off a key DNA repair system in the developing nervous system is linked to smaller brain size as well as problems in brain structures vital to movement, memory and emotion, according to new research led by St. Jude Children's Research Hospital scientists.

27 Jul 2009

Autophagy helps HIV to proliferate

Not satisfied with simply thwarting its host's defensive maneuvers, HIV actually twists one to its advantage, based on new findings from Kyei et al. in the July 27, 2009 issue of the Journal of Cell Biology. Vojo Deretic and colleagues suggest that autophagy - a stress response process - helps HIV to proliferate and that conversely, blocking autophagy lessens HIV production.

27 Jul 2009

Enzyme implicated in blood flow in Alzheimer’s, disease progression

Researchers have discovered that the enzyme, endothelin converting enzyme-2 (ECE-2), may cause the decrease in blood flow in the brain seen in Alzheimer's disease and contribute to progression of the disease.

27 Jul 2009

Seattle Genetics starts Brentuximab Vedotin retreatment trial

Seattle Genetics, Inc. has announced that it has initiated a phase II clinical trial of brentuximab vedotin (SGN-35), an antibody-drug conjugate (ADC), for the retreatment of patients with Hodgkin lymphoma and systemic anaplastic large cell lymphoma (ALCL).

27 Jul 2009

Scientists create baby mice from mouse stem cells

In groundbreaking research scientists from China have for the first time created baby mice by using powerful stem cells from adult mouse skin.

27 Jul 2009

Research builds on previous Par-4 study that produced cancer-resistant mouse

Human cells are able to secrete a cancer-killing protein, scientists at the University of Kentucky's Markey Cancer Center have found.

26 Jul 2009

Sticky protein protects cells from mechanical stress

A new study by scientists at the University of Iowa shows why muscle membranes don't rupture when healthy people exercise.

26 Jul 2009

Surgery after chemotherapy and radiation can be an option for patients advanced lung cancer

In recent years, oncologists have debated whether patients with a certain type of advanced lung cancer would benefit from surgery.

26 Jul 2009

Bones from stem cell technology

Scientists are closer to understanding how to grow replacement bones with stem cell technology, thanks to research published today in the journal Nature Materials.

26 Jul 2009

Discovery of key event in prostate cancer progression

A study led by researchers at the Ohio State University Comprehensive Cancer Center and Dana-Farber Cancer Institute reveals how late-stage, hormone-independent prostate tumors gain the ability to grow without need of hormones.

24 Jul 2009

Growth factor enhances heart regeneration, improves heart function without need for cardiac stem cells

Injured heart tissue normally can't regrow, but researchers at Children's Hospital Boston have now laid the groundwork for regenerating heart tissue after a heart attack, in patients with heart failure, or in children with congenital heart defects.

24 Jul 2009

Caspase-8 protein plays an important role in proliferation and invasion of cancer cells

Scientists at Burnham Institute for Medical Research have found that the Caspase-8 protein, long known to play a major role in promoting programmed cell death (apoptosis), helps relay signals that can cause cancer cells to proliferate, migrate and invade surrounding tissues. The study was published in the journal Cancer Research on June 15.

24 Jul 2009

New drug may reduce heart attack damage

A novel drug that targets a master disease-causing gene can dramatically reduce heart muscle damage after a heart attack and may lead to significantly improved patient outcomes, researchers at the University of New South Wales (UNSW) have shown.

22 Jul 2009

Young adults face tough time getting health insurance

Young adults are facing tough times with limited job prospects and no health insurance. The Associated Press reports on recent college graduate Emily Weinstein as being representative of the many young uninsured Americans: "Like millions of other uninsured adults in their 20s, Weinstein is watching Congress as it advances legislation to overhaul health care.

22 Jul 2009

Camera-phone uses blood, saliva samples to diagnose disease

Researchers at the University of California, Berkeley, have developed a "prototype camera-phone mounted with a microscope" that can "magnify and photograph blood or saliva samples" for diagnosing diseases, the Canadian Press/Google.com reports.

22 Jul 2009

NovaSterilis receives patent for vaccine creation using supercritical carbon dioxide

NovaSterilis Inc., a developer of supercritical carbon dioxide technology for biomedical applications, announces the issue of US Patent 7,560,113 for creation and production of whole cell vaccines with supercritical carbon dioxide (SCCO2)*.

22 Jul 2009

Migrant neuron: New imaging studies reveal mechanics of neuron migration

The development of the brain proceeds a little like the European settlement of North America. The earliest pioneers settled on the east coast with subsequent waves of settlers forming communities further and further westward. In cortical regions of the developing brain, generations of young neurons undergo a staged migration as well, with the earliest-born cells staying relatively close to their birthplace and subsequent generations traveling further, ultimately stratifying into six neuronal layers in the mature brain. Now, for the first time, imaging studies have identified the "motors" that propel a unique form of cell migration that creates these layers that

22 Jul 2009