T Cell News and Research

Latest T Cell News and Research

New understanding of anti-malarial drug resistance

Researchers at Georgetown University Medical Center say they are moving closer to understanding why the most lethal form of human malaria has become resistant to drug treatment in the past three decades.

8 Jun 2007

In mice, drug protects against diabetes and atherosclerosis

Blocking a single protein with an experimental drug prevented and treated both type 2 diabetes and atherosclerosis in laboratory mice that had been fed unhealthy diets and were genetically predisposed to these common killers, according to an article published online in Nature.

8 Jun 2007

HIV uses pathways to infect cells

Like hobos on a train, HIV, the virus that causes AIDS, uses a pre-existing transport system to leave one infected cell and infect new ones, Hopkins scientists have discovered.

8 Jun 2007

Mouse hibernation hormones described

A key hormone enables starving mice to alter their metabolism and “hibernate” to conserve energy, revealing a novel molecular target for drugs to treat human obesity and metabolic disorders, UT Southwestern Medical Center researchers have found.

8 Jun 2007

New gene influences susceptibility to late-onset Alzheimer's disease

A new gene that influences susceptibility to late-onset Alzheimer's disease (LOAD) has been identified by an international research team that analyzed the genomes of more than a thousand people with and without the disorder.

8 Jun 2007

Ethically universal stem cell lines

Human embryonic stem cells (hESC), those very young cells that are a biological blank slate, have the potential to become more specialized, contributing to the workings of a wide variety of organs and tissues.

8 Jun 2007

Combination therapy reduces tumor resistance to radiation

Radiation is used to treat a variety of tumors and the response of tumors to radiation is dependent on endothelial cell death, which in turn limits oxygen delivery to the tumor, causing hypoxia and tumor cell death.

8 Jun 2007

Blocking the action of beta1-integrin to treat cancer

Targeting the function of a protein known as beta1-integrin might represent a novel approach to cancer treatment, according to a paper published online in the EMBO Journal.

8 Jun 2007

Reprogrammed fibroblasts resemble embryonic stem cells

Stem cell biology takes another exciting leap forward as scientists report that normal tissue cells can be reprogrammed to exhibit many of the properties that are characteristic of embryonic stem cells, including the ability to give rise to multiple cell types and contribute to the germline.

8 Jun 2007

Aging stem cells in mice may hold answers to diseases of the aged

As stem cells in the blood grow older, genetic mutations accumulate that could be at the root of blood diseases that strike people as they age, according to work done in mice by researchers at the Stanford University School of Medicine.

8 Jun 2007

Researchers find stem cells in colorectal tumors

Researchers at the Stanford University School of Medicine have identified the cancer stem cells that propagate tumors in colon and rectal cancer, a discovery that could lead to improved treatment of this deadly cancer.

5 Jun 2007

Researchers track how spores break out of dormant state

Tapping into the unknown world of awakening dormant bacterial spores, researchers have revealed through atomic force microscopy (AFM) the alterations of spore coat and germ cell wall that accompany the transformation from a spore to a vegetative cell.

5 Jun 2007

Researchers track human stem cells transplanted into rat brain

Researchers at the Stanford University School of Medicine have illuminated the path taken by human neural stem cells that were transplanted into the brains of rats and mice, and found that the cells successfully navigate toward areas damaged by stroke.

5 Jun 2007

Blocking stress protein decreases Alzheimer's peptide

Scientists revealed in November 2006 that stress increases production in mice of a brain peptide critical to Alzheimer's disease.

5 Jun 2007

breakthrough in the treatment of idiopathic pulmonary haemosiderosis

Researchers at Queen Mary University London and the University of Leicester and have announced a potential breakthrough in the treatment of a rare but devastating medical condition that can affect children and young people.

5 Jun 2007

Vorinostat shows anti-cancer activity in recurrent gliomas

North Central Cancer Treatment Group (NCCTG) researchers, based at Mayo Clinic in Rochester, Minn., report that a novel application of the drug vorinostat shows activity in patients with recurrent glioblastoma multiforme.

5 Jun 2007

Tumor cell activity may provide clues for treating breast cancer in young women

When women under 50 develop breast cancer the disease tends to be more aggressive and less responsive to treatment than when it occurs in older women.

5 Jun 2007

Circulating tumor cells predict how prostate cancer patients do with chemotherapy

The number of tumor cells circulating in the bloodstream of patients with metastatic, hormone-resistant, prostate cancer can predict how they will do with chemotherapy, according to results of an international trial.

5 Jun 2007

Revlimid may change the way physicians treat multiple myeloma

Findings from a Phase III study by the Eastern Cooperative Oncology Group (ECOG 4A03) were presented yesterday at the American Society of Clinical Oncology (ASCO) meeting in Chicago and demonstrate the benefits of using Revlimid (lenalidomide) with reduced doses of the steroid dexamethasone.

5 Jun 2007

Results of phase II studies of pazopanib

GlaxoSmithKline (GSK) has announced results from ongoing Phase II studies of pazopanib in advanced or metastatic renal cell carcinoma (RCC) and ovarian cancer.

5 Jun 2007