T Cell News and Research

Latest T Cell News and Research

Risk of secondary malignancies in testicular cancer

While in the United States the preferred treatment for stage I mixed germ cell tumors has been retroperitoneal lymphadenectomy, adjuvant chemotherapy has been more commonly used in Europe.

2 May 2006

Epstein reviews recommendations for rebiopsy in patients with high grade pin or atypical foci in prostate biopsy

In the era before extended biopsy schemes, patients with prostate biopsy results showing high grade prostatic intraepithelial neoplasia were recommended for re-biopsy in 3 to 6 months.

2 May 2006

Vacuum-assisted closure device may be beneficial in penile skin graft reconstruction

Skin defects of the penile shaft pose a significant reconstructive problem.

2 May 2006

Possible target for future therapies aimed at delaying or stopping Alzheimer's disease

Researchers at Oregon Health & Science University's Neurological Sciences Institute (NSI) have located a possible target for future therapies aimed at delaying or stopping Alzheimer's disease.

2 May 2006

Sperm-producing stem cells found in testicles could be extracted, grown in the lab, and frozen for future use

Men may cringe at the idea, but sperm-producing stem cells found in testicles could be extracted, grown in the lab, and frozen for future use.

2 May 2006

DNA taxi

Despite few successes to date, gene therapy is a highly promising approach for medical therapy in the future.

1 May 2006

Peplin announces positive results of skin cancer trial

Peplin Limited today announced positive results from its Australian phase IIa clinical trial of its proprietary drug PEP005 Topical in superficial forms of basal cell carcinoma (sBCC) the most common form of skin cancer.

1 May 2006

New method found showing how nerve cells can selectively filter and transfer signals

Scientists from Gvttingen and Bochum find evidence for a new mechanism, with which our nerve cells are able to filter signals and transfer them selectively.

28 Apr 2006

Transplanted stem cells hoped to be able to regenerate damaged heart muscle in first heart attack victims

Rush cardiologists are hoping that transplanted stem cells can regenerate damaged heart muscle in those who experience a first heart attack. The study involves an intravenous infusion of adult mesenchymal stem cells from healthy donor bone marrow that might possibly reverse damage to heart tissue.

28 Apr 2006

Combinatorial approach found to reverse the onset of type 1 diabetes

A major finding, which represents an important step toward a potential cure for type 1 (insulin-dependent) diabetes, has been made by a research team at the La Jolla Institute for Allergy & Immunology (LIAI). The team, led by Matthias von Herrath, M.D., an internationally recognized expert on the molecular basis of type 1 diabetes, used a combinatorial treatment approach in laboratory mice and found it reversed recent onset type 1 diabetes in the majority of animals tested.

28 Apr 2006

Study indicates how drug efficacy can be increased by manipulating the signalling mechanism

Researchers believe they have found a way to change the action of 60 percent of currently available medications, in some cases making them many times more effective, according to an article published in the April 21 edition of the journal Science. The discovery has the potential to improve treatments for diseases including heart disease, cancer, diabetes, depression and arthritis. The study describes a new way to manipulate perhaps the most important signaling mechanism in human cells: G-protein coupled receptors (GPCRs).

28 Apr 2006

Researchers figure out how nuclear pores duplicate before cells divide

Researchers have long wondered how nuclear pores - the all-important channels that control the flow of information in and out of a cell's nucleus - double in number to prepare for the split to come when a cell divides. Now, for the first time, scientists at the Salk Institute for Biological Studies watched as new funnel-like pore structures formed from scratch, and inserted themselves into the nuclear membrane.

28 Apr 2006

Finding indicate why some kinds of Leukemia are more aggressive than others

New clues to why some kinds of leukemia are more aggressive and deadly than others are coming from research examining the types of genetic damage that allow some blood cells to grow out of control, scientists report.

28 Apr 2006

Polycomb proteins key factors in influencing the direction of embryonic stem cell development

Embryonic stem cells may one day provide a means to treat disease, but according to two new reports, they are already revealing remarkable insights into the mysteries of human biology. How humans manage to develop from a single fertilized egg into the trillions of cells that make up a mature adult remains a poorly understood process. Now, using both human and mouse embryonic stem cells, researchers have mapped how a key developmental ingredient controls the genome.

28 Apr 2006

Discovery brings embryonic stem cell medicine a step closer

A team of scientists announced a critical step on the path of realizing the promise of embryonic stem (ES) cells for medicine. The researchers have discovered unique molecular imprints coupled to DNA in mouse ES cells that help explain the cells' rare ability to form almost any body cell type. These imprints, or "signatures," appear near the master genes that control embryonic development and probably coordinate their activity in the early stages of cell differentiation. Not only do these findings help to unlock the basis for ES cells' seemingly unlimited potential, they also suggest ways to understand why ordinary cells are so limited in their abilities to repair or replace damaged cells.

26 Apr 2006

Studies indicate stem cells are flexible enough to become any cell in the body

Two studies in the April 21, 2006 Cell report new details of the "genetic program" that affords embryonic stem cells the flexibility to give rise to any cell type in the body. Both groups identified mechanisms by which the embryonic stem cells of mice or humans keep from going down any one particular developmental path--that of muscle or nervous tissue, for example--while remaining "poised for activation."

26 Apr 2006

Studies indicate stem cells are flexible enough to become any cell in the body

26 Apr 2006

Osteoporosis could be caused by factors other than declining estrogen levels

New evidence in the April 21, 2006 Cell challenges the long-standing notion that declining estrogen levels alone lead to osteoporosis after women go through menopause. The researchers rather found that high levels of pituitary-derived follicle-stimulating hormone (FSH) cause bone loss in mice. The pituitary is a master gland found at the base of the brain.

26 Apr 2006

Enhancing the function of the protein SOCS3 could be a more effective way to regulate cell responses

A discovery made at The Walter and Eliza Hall Institute provides new insights into enhancing the function of the protein SOCS3, which regulates the response of cells to external stimuli.

26 Apr 2006

Protein made by cancer virus explains how the virus spreads

New research shows that a protein made by a cancer virus causes infected immune cells to cling to other immune cells, enabling the virus to spread.

26 Apr 2006

T Cell News and Research

Latest T Cell News and Research

Risk of secondary malignancies in testicular cancer

Epstein reviews recommendations for rebiopsy in patients with high grade pin or atypical foci in prostate biopsy

Vacuum-assisted closure device may be beneficial in penile skin graft reconstruction

Possible target for future therapies aimed at delaying or stopping Alzheimer's disease

Sperm-producing stem cells found in testicles could be extracted, grown in the lab, and frozen for future use

DNA taxi

Peplin announces positive results of skin cancer trial

New method found showing how nerve cells can selectively filter and transfer signals

Transplanted stem cells hoped to be able to regenerate damaged heart muscle in first heart attack victims

Combinatorial approach found to reverse the onset of type 1 diabetes

Study indicates how drug efficacy can be increased by manipulating the signalling mechanism

Researchers figure out how nuclear pores duplicate before cells divide

Finding indicate why some kinds of Leukemia are more aggressive than others

Polycomb proteins key factors in influencing the direction of embryonic stem cell development

Discovery brings embryonic stem cell medicine a step closer

Studies indicate stem cells are flexible enough to become any cell in the body

Studies indicate stem cells are flexible enough to become any cell in the body

Osteoporosis could be caused by factors other than declining estrogen levels

Enhancing the function of the protein SOCS3 could be a more effective way to regulate cell responses

Protein made by cancer virus explains how the virus spreads

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

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