T Cell News and Research

Latest T Cell News and Research

Researchers move in on novel therapeutics to inhibit melanoma

Northwestern University researchers have developed a novel, three-dimensional model that allows scientists to observe how interacting with the microenvironment of metastatic melanoma cells induces normal skin cells to become similar to aggressive cancer cells that migrate and spread throughout the body.

5 Dec 2005

Researchers detail mechanism of stroke

In the neural train wreck that is stroke, the cutoff of oxygen kills brain cells through a buildup of acid, as well as by overexciting receptors on the surface of brain cells.

5 Dec 2005

Unexpected link between muscular dystrophy and muscle wasting associated with cancer

A new study provides important insight into the mechanisms of a muscle wasting disorder that interferes with treatment for cancer and has a negative impact on patient survival.

5 Dec 2005

HRAS mutation analysis in Costello Syndrome

Gene mutations in the HRAS sequence are present in most patients affected with Costello syndrome, according to a new study in the American Journal of Medical Genetics. The mutations occurred de novo in patients, meaning, they were not observed in their parents' genes.

5 Dec 2005

Significant relationships between household endotoxin and diagnosed asthma

Exposure to household endotoxin levels poses a significant risk for asthma, according to the first nationwide sampling of house dust.

2 Dec 2005

Disruption of normal gene interaction linked to schizophrenia

Disruption of the normal interaction between the genes PRODH and COMT contributes directly to major symptoms of schizophrenia by upsetting the balance of the brain chemicals glutamate and dopamine, according to a group of investigators that includes a scientist now at St. Jude Children's Research Hospital.

2 Dec 2005

Inhibition of FLT3 signaling targets DCs to ameliorate autoimmune disease

Scientists at the Johns Hopkins Kimmel Cancer Center have found that a gene pathway linked to a deadly form of leukemia may provide a new way to treat autoimmune diseases, including multiple sclerosis.

2 Dec 2005

Bisphenol A (BPA) has been linked to damage in developing brain tissue

The chemical bisphenol A (BPA), widely used in products such as food cans, milk container linings, water pipes and even dental sealants, has now been found to disrupt important effects of estrogen in the developing brain.

2 Dec 2005

Cellular and molecular mechanisms that accelerate the development and progression of atherosclerosis

A McMaster University study on atherosclerosis will be featured on the cover of the December issue of the high impact American Heart Association scientific journal, Arteriosclerosis, Thrombosis and Vascular Biology.

2 Dec 2005

Protein target for Parkinson's disease

Researchers at Johns Hopkins' Institute for Cell Engineering (ICE) have discovered a protein that could be the best new target in the fight against Parkinson's disease since the brain-damaging condition was first tied to loss of the brain chemical dopamine.

2 Dec 2005

New anthrax antibody

A new anthrax antibody engineered by scientists at The University of Texas at Austin protects and defends against inhalation anthrax without the use of antibiotics and other more expensive antibodies.

2 Dec 2005

Spinal cord cells to be repaired by using nose cells

Plans are afoot next year for British surgeons to attempt to make the first repairs of spinal cord nerves using a revolutionary new stem cell technique.

30 Nov 2005

Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia

Most people with a rare type of dementia called primary progressive aphasia (PPA) have a specific combination of prion gene variants, a new study shows.

28 Nov 2005

Exploiting biology's own chemical toolbox...

Exploiting biology's own chemical toolbox, researchers have developed a new technique that will allow them to modify specific sequences within a DNA molecule. The approach will not only help reveal the impact of biochemical alterations to DNA, but could have far-reaching implications for DNA-based medical diagnosis and nanobiotechnology.

28 Nov 2005