T Cell News and Research

Latest T Cell News and Research

Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

Duke University researchers have now shown that selectively killing the population of regulatory T cells in cancer patients - cells that normally function to restrain the activity of the immune response - improves the ability of a cancer vaccine to stimulate tumor-specific T cells.

28 Nov 2005

GRK5's role in restenosis

Researchers at Jefferson Medical College have begun to clarify the role of a protein - and potential drug target - in the process by which arteries re-clog after treatment.

28 Nov 2005

Coaxing human embryonic stem cells to make dopamine

For all of the promise embryonic stem cells hold for therapies for neurodegenerative diseases such as Parkinson's disease, they are notoriously difficult to use.

28 Nov 2005

Study finds AKT blocks cancer cell motility

PIn investigating the molecular mechanisms of cancer cell motility - the unique property that enables cancer to spread from its primary origin to other parts of the body - researchers have uncovered a surprising role for the AKT/PKB (protein kinase B) enzyme

26 Nov 2005

Zinc supplements safe for chidren with HIV

Zinc-deficient children living in communities where they do not receive adequate amounts of zinc from their diet should be given supplements, even if they are HIV-infected, according to researchers from the Johns Hopkins Bloomberg School of Public Health and other institutions.

26 Nov 2005

Researchers gain detailed view yet of the heart of the translocon

Researchers have gained the most detailed view yet of the heart of the translocon, a channel through which newly constructed proteins are inserted into the cell membrane. The process of transporting proteins across or into membranes is a critical function that occurs in every cell.

26 Nov 2005

Cellular clues to vitamin A resistance in lung cancer

Vitamin A deficiency has been associated with the development of lung cancer in laboratory studies. However, clinical trials of natural and synthetic derivatives of vitamin A, called retinoids, for the prevention of lung cancer have been largely unsuccessful in the general population.

26 Nov 2005

Potential drug target for malaria

Researchers have identified an enzyme crucial to the malaria parasite's invasion of red blood cells, according to a study in the open-access journal, PLoS Pathogens.

26 Nov 2005

Two novel drugs kill breast cancer tumor cells

Two new drugs, when combined, killed up to 75 percent of breast cancer tumor cells in mice and suppressed the regrowth of tumors, according to researchers at the Virginia Commonwealth University Massey Cancer Center.

26 Nov 2005

New door opens for anti-aging research in humans

A counterintuitive experiment has resulted in one of the longest recorded life-span extensions in any organism and opened a new door for anti-aging research in humans.

26 Nov 2005

New and promising antibody profiling technique to test for non-small cell lung cancer cases

Biomedical scientists have revealed a new and promising antibody profiling technique that provides a high degree of early diagnostic accuracy for non-small cell lung cancer cases.

26 Nov 2005

Thrombospondin (TSP-1) can cause kidney failure when normal blood flow is disrupted

Scientists led by a University of Cincinnati (UC) kidney expert have found that a naturally occurring protein that normally fights cancer cells can also cause severe kidney failure when normal blood flow is disrupted.

26 Nov 2005

Sugary drinks push Latino kids toward type 2 diabetes

Overweight Latino children who consume lots of sugar-especially in sugary drinks-show signs of beta cell decline, a precursor of type 2 diabetes, according to researchers at the Keck School of Medicine of the University of Southern California.

26 Nov 2005

Tuberculosis research

It is estimated that two billion people--or one-third of the world's population--are chronically infected without active symptoms. Nine million new cases of active disease are diagnosed annually, resulting in two million deaths.

26 Nov 2005

Researchers identify genes affected by Methotrexate (MTX)

A Queen's University study of fruit flies that may revolutionize the way birth defects are studied has identified the genes affected by a widely-prescribed drug known to cause birth defects.

26 Nov 2005

Fear gene discovered

In the Nov. 18 issue of Cell, researchers report the discovery of a gene that controls the ability to react with appropriate fear to impending danger.

26 Nov 2005

South Korean cloning pioneer responds to accusations

South Korean cloning pioneer Hwang Woo-suk has defended himself in the media following allegations over ethics violations that have seen his groundbreaking work plunged into controversy.

24 Nov 2005

Compound from Salinispora (marine bacteria) kills blood cancer cells

An anti-cancer compound derived from bacteria dwelling in ocean-bottom sediments appears in laboratory tests to be a potent killer of drug-resistant multiple myeloma cells, and potentially with less toxicity than current treatments, report Dana-Farber Cancer Institute researchers in the November issue of Cancer Cell.

21 Nov 2005

Carbonic anhydrase and CO2 sensing during Cryptococcus neoformans growth, differentiation, and virulence

By using pathogenic fungi as model systems for understanding fungal diseases, two groups of researchers are reporting new work that offers insight into how carbon dioxide (CO2) governs the morphogenic changes that allow pathogenic fungi to survive in different environments and invade the human body

21 Nov 2005

Critical role of p53 gene

Fruit flies can live significantly longer, and remain healthy, when activity of the fly version of the tumor-suppressing protein p53 is reduced in nerve cells.

21 Nov 2005