T Cell News and Research

Latest T Cell News and Research

3D bioengineered model could reveal new treatments for deadly lung disease

A 3D bioengineered model of lung tissue built by University of Michigan researchers is poking holes in decades worth of flat, Petri dish observations into how the deadly disease pulmonary fibrosis progresses.

14 Sep 2020

Researchers receive $2.5 million grant to develop and analyze breast tumor organoids

Breast cancer is the second most common cancer diagnosed in women in the United States after skin cancer, and women with comorbidities (the presence of more than one condition/disease) often fare worse in terms of their breast cancer.

14 Sep 2020

Oxford University and AstraZeneca resume COVID-19 vaccine trial

More than a hundred candidate vaccine trials against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19), are underway. About 35 are now undergoing clinical evaluation, and of these, nine are in the final phase of human trials, including the vaccine developed by Oxford University and the biopharmaceutical firm, AstraZeneca.

14 Sep 2020

Tiny antibody component shows high potency in SARS-CoV-2 animal models

University of Pittsburgh School of Medicine scientists have isolated the smallest biological molecule to date that completely and specifically neutralizes the SARS-CoV-2 virus, which is the cause of COVID-19.

14 Sep 2020

Circadian rhythm affects SARS-CoV-2 infection and host immune response

In an interesting bioRxiv preprint paper, French researchers show that the time day can affect infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as guide subsequent host immune response – implying that circadian rhythm may well be a novel target for managing viral progression.

14 Sep 2020

Research finds genetic factors that protect from chronification of migraines

According to existing estimates, migraine is a highly prevalent ailment, with about 15 percent of global population suffering from it at one time or another.

14 Sep 2020

Keto diet could be beneficial for elderly COVID-19 patients

A recent study by researchers at Yale School of Medicine, New York University Langone Health and Washington University School of Medicine, claims that the ketogenic diet (high fat, low carbohydrate diet) is capable of mitigating clinical outcomes of coronavirus disease 2019 (COVID-19) in elderly people by improving immune-metabolic functions and reducing inflammation. The study is currently available on the bioRxiv* preprint server.

14 Sep 2020

UofL receives $11.5 million to accelerate the development of new immunotherapies

Cancer remains one of the most difficult and deadly challenges in human health, affecting Kentuckians at a higher rate than residents of any other state and killing more than 600,000 people each year in the U.S. alone.

14 Sep 2020

Computational models screen for coronaviruses likely to infect humans

The researchers from Rochester Institute of Technology and the Hauptmann-Woodward Medical Research Institute produced models of the receptor-binding domain (RBD) found on outbreak strains of betacoronaviruses and its interaction with the host cell receptor angiotensin-converting enzyme 2 (ACE2).

14 Sep 2020

Sticky DNA webs may cause tissue damage associated with severe COVID-19 infections

Sticky webs of DNA released from immune cells known as neutrophils may cause much of the tissue damage associated with severe COVID-19 infections, according to two new studies published September 14 in the Journal of Experimental Medicine.

14 Sep 2020

Researchers identify microRNA molecules that could repress the replication of human coronaviruses

HSE University researchers have found microRNA molecules that are potentially capable of repressing the replication of human coronaviruses, including SARS-CoV-2.

14 Sep 2020

Supplements of Human Milk Oligosaccharides may help improve gut health in adults

Supplements of Human Milk Oligosaccharides (HMOs), the sugars found in breast milk, may help improve the gut health of adults, according to new research carried out at the Quadram Institute.

14 Sep 2020

TRESK regulates the brain's circadian clock to differentiate behavior between day and night

Research from the University of Kent has found that TRESK, a calcium regulated two-pore potassium channel, regulates the brain's central circadian clock to differentiate behavior between day and night.

14 Sep 2020

Cell signaling research rings warning bells over an emerging cancer drug target

Researchers at the Babraham Institute have used their understanding of cellular signalling to highlight a pitfall in an emerging treatment for cancer and inflammation.

14 Sep 2020

Single-molecule imaging of SARS-CoV-2 spikes on virus particles

Using single-molecule FRET analysis, a team of researchers has revealed how the different conformations of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein are interconnected. Figuring out the different conformations in real-time and which conformations antibodies prefer may help design effective vaccines and drugs. The research is published on the preprint server bioRxiv*.

14 Sep 2020

Researchers identify the missing link in the production of nitric oxide

Some microorganisms, the so-called methanotrophs, make a living by oxidizing methane (CH4) to carbon dioxide (CO2). Ammonia (NH3) is structurally very similar to methane, thus methanotrophs also co-metabolize ammonia and produce nitrite.

14 Sep 2020

Tobacco plant promotes tissue adhesion and can maintain grafts between different species

Grafting is a horticultural technique that joins plants together by means of tissue regeneration, combining desirable characteristics of both plants. Generally, grafts have been thought to be compatible only between the same or closely related species.

14 Sep 2020

Potential sea animal reservoirs for coronaviruses?

The COVID-19 pandemic has focused, yet again, intense research interest on coronaviruses, due to the high toll the novel coronavirus SARS-CoV-2 has taken on human life, health, economic well-being, and social activity. A recent paper published on the server Preprints in September 2020 reviews what is known about this viral infection in water life.

13 Sep 2020

A map of SARS-CoV-2 escape mutations enables the development of therapeutic antibody cocktails

A recent tour-de-force study by the US researchers describes a comprehensive approach to completely map mutations to the SARS-CoV-2 receptor-binding domain (RBD) that escape antibody binding – enabling, in turn, rational design of antibody therapeutics and appraisal of the antigenic consequences of viral evolution. The results are currently available in a bioRxiv preprint paper.

13 Sep 2020

Shedding light on altered blood cell traits involved in severe COVID-19

Researchers at the University of Georgia in the United States have shed light on the pathological mechanisms underlying the association between the genetic locus 3p21.31 and severe coronavirus disease 2019 (COVID-19).

13 Sep 2020

T Cell News and Research

Latest T Cell News and Research

3D bioengineered model could reveal new treatments for deadly lung disease

Researchers receive $2.5 million grant to develop and analyze breast tumor organoids

Oxford University and AstraZeneca resume COVID-19 vaccine trial

Tiny antibody component shows high potency in SARS-CoV-2 animal models

Circadian rhythm affects SARS-CoV-2 infection and host immune response

Research finds genetic factors that protect from chronification of migraines

Keto diet could be beneficial for elderly COVID-19 patients

UofL receives $11.5 million to accelerate the development of new immunotherapies

Computational models screen for coronaviruses likely to infect humans

Sticky DNA webs may cause tissue damage associated with severe COVID-19 infections

Researchers identify microRNA molecules that could repress the replication of human coronaviruses

Supplements of Human Milk Oligosaccharides may help improve gut health in adults

TRESK regulates the brain's circadian clock to differentiate behavior between day and night

Cell signaling research rings warning bells over an emerging cancer drug target

Single-molecule imaging of SARS-CoV-2 spikes on virus particles

Researchers identify the missing link in the production of nitric oxide

Tobacco plant promotes tissue adhesion and can maintain grafts between different species

Potential sea animal reservoirs for coronaviruses?

A map of SARS-CoV-2 escape mutations enables the development of therapeutic antibody cocktails

Shedding light on altered blood cell traits involved in severe COVID-19

Immunology eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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