T Cell News and Research

Latest T Cell News and Research

Biomarker for earlier diagnosis of neurodegenerative diseases detected in the eye

A new study led by Boston Medical Center researchers indicates a well-known biomarker that serves as a marker for earlier diagnosis of neurodegenerative diseases is now detectable in the eye.

21 Sep 2020

Immunotherapy benefits patients with gastric and esophageal cancers, new data shows

New data presented at ESMO 2020 have shown that immunotherapy is beneficial for patients with gastric and esophageal cancers who currently have poor survival.

21 Sep 2020

Research uncovers potential cause of neurotoxicity due to immunotherapy

New research has uncovered the previously unknown presence of CD19 -- a B cell molecule targeted by chimeric antigen receptor (CAR) T cell immunotherapy to treat leukemia, lymphoma, and multiple myeloma -- in brain cells that protect the blood brain barrier (BBB).

21 Sep 2020

Researchers generate accurate replications of human retinas in a dish

Scientists have generated accurate replications of human retinas in culture that can be used to pinpoint the specific types of cells affected by genetic eye diseases.

21 Sep 2020

Astrocytes are essential for blood-brain barrier health, shows study

Hard skulls help protect our brains from physical injuries.In addition to a tough outer shell, brains have internal defenses, including a powerful shield called the blood-brain barrier that defends brain cells from substances in the bloodstream that are toxic and dangerous to nerve cells. If the blood-brain barrier is breached, then health problems arise.

21 Sep 2020

Psoriatic arthritis may be activated by the same trigger in different patients, study reveals

A new study has revealed psoriatic arthritis may be activated by the same trigger in different patients. Researchers from the University of Oxford and the Wellcome Sanger Institute identified high levels of a specific receptor in immune cells from psoriatic arthritis patients, giving the strongest evidence yet of a single cause for the disease

21 Sep 2020

Researchers identify a compound that inhibits growth of schwannomas

Schwannomas are tumors of the peripheral nervous system, which often occur in the genetic disease neurofibromatosis type 2. The research group of Prof. Dr. Helen Morrison at the Leibniz Institute on Aging - Fritz Lipmann Institute in Jena, Germany, identified a compound that inhibits the growth of such tumors and improves nerve function.

21 Sep 2020

Soluble ACE2 microbody blocks SARS-CoV-2 entry into lung cells

A new study by researchers at NYU Langone Medical Center and Weill Cornell Medical College and published on the preprint server bioRxiv* in September 2020 reports the potential of an angiotensin-converting enzyme 2 (ACE2)-antibody Fc complex in a new format that seems to offer more significant inhibition of SARS-CoV-2.

21 Sep 2020

Post-operative radiotherapy in NSCLC shows no statistically difference in 3-year disease-free survival

Post-operative radiotherapy (PORT) used in patients with non-small-cell lung cancer (NSCLC) following complete resection and after (neo) adjuvant chemotherapy shows no statistically significant difference in 3-year disease-free survival (DFS), according to data presented at ESMO 2020.

21 Sep 2020

KRASG12C inhibitor sotorasib shows durable clinical benefits for solid cancers

In a Phase I clinical trial for patients with advanced solid cancers marked by KRAS G12C mutations, the KRASG12C inhibitor sotorasib (AMG 510) resulted in manageable toxicities and durable clinical benefits.

21 Sep 2020

Researchers assess similarity of couples in pathophysiological mechanisms of type 2 diabetes

New research being presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD), held online this year, shows that when one half of a couple shows high levels of certain behaviours that prevent type 2 diabetes, such as good diet or exercise, that behaviour also tends to be high in the other half of the couple.

21 Sep 2020

In vitro testing suggests effective novel drug combinations for SARS-CoV-2

A recent study published on the preprint server bioRxiv* in September 2020 shows the value of drug combinations to enhance the therapeutic and preventive efficacy of such repositioned drugs in standard antiviral therapy.

20 Sep 2020

Lopinavir-ritonavir does not suppress SARS-CoV-2 activity in vitro

Among them is the combination of lopinavir and ritonavir, which have been in use in an attempt to reduce the severity of the disease. However, a new South Korean study published on the preprint server bioRxiv in September 2020 shows that this combination is ineffective against the virus.

20 Sep 2020

Study identifies new regions of positive selection in SARS-CoV-2

Based on structural modeling of ribonucleic acid (RNA) and proteins, the researchers from Duke University argue that newly identified regions of positive selection in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) likely affect species-specific RNA instead of protein function – improving our understanding of the molecular mechanisms responsible for highly unique biological properties of this virus.

20 Sep 2020

Researchers try and pop SARS-CoV-2 with an AFM tip - virion surprisingly resilient

Researchers at Semmelweis University and the National Public Health Center in Hungary have conducted an imaging study showing that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent responsible for coronavirus disease 2019 (COVID-19), is a highly dynamic and resilient virus

20 Sep 2020

Novel sequencing method could be useful for COVID-19 research

Researchers at the University of Chicago and the Cleveland Clinic have presented a novel single-cell RNA sequencing method that could be a useful application for research into the current coronavirus disease 2019 (COVID-19) pandemic.

20 Sep 2020

Trial shows new first-line treatment option for patients with metastatic kidney cancer

The results of the phase 3 CheckMate 9ER trial have provided a new first-line treatment option for patients with metastatic kidney cancer. The late breaking results are presented at ESMO 2020.

19 Sep 2020

Research identifies new alteration in the brain of people with Alzheimer's

Despite the important advances in research in recent years, the etiopathogenesis of Alzheimer's disease is still not fully clarified. One of the key questions is to decipher why the production of beta amyloid, the protein that produces the toxic effect and triggers the pathology, increases in the brain of people with Alzheimer's.

19 Sep 2020

Scientists identify new drug to prevent SARS-CoV-2 infection consequences

Scientists from the Department of Cell Biology of the University of Malaga and the Andalusian Centre for Nanomedicine and Biotechnology have made progress in finding new rapid implementation therapies to combat the COVID-19 pandemic, identifying a new drug that could prevent or mitigate the consequences derived from SARS-CoV-2 infection.

19 Sep 2020

Research provides deeper understanding of how neurons in the nose react to odors

Take a sniff of a freshly poured glass of wine, and the prevailing scientific thinking would suggest that the harmony of fragrances you perceive starts with sensory receptors in your nose simply adding up the individual odors they encounter.

19 Sep 2020

T Cell News and Research

Latest T Cell News and Research

Biomarker for earlier diagnosis of neurodegenerative diseases detected in the eye

Immunotherapy benefits patients with gastric and esophageal cancers, new data shows

Research uncovers potential cause of neurotoxicity due to immunotherapy

Researchers generate accurate replications of human retinas in a dish

Astrocytes are essential for blood-brain barrier health, shows study

Psoriatic arthritis may be activated by the same trigger in different patients, study reveals

Researchers identify a compound that inhibits growth of schwannomas

Soluble ACE2 microbody blocks SARS-CoV-2 entry into lung cells

Post-operative radiotherapy in NSCLC shows no statistically difference in 3-year disease-free survival

KRASG12C inhibitor sotorasib shows durable clinical benefits for solid cancers

Researchers assess similarity of couples in pathophysiological mechanisms of type 2 diabetes

In vitro testing suggests effective novel drug combinations for SARS-CoV-2

Lopinavir-ritonavir does not suppress SARS-CoV-2 activity in vitro

Study identifies new regions of positive selection in SARS-CoV-2

Researchers try and pop SARS-CoV-2 with an AFM tip - virion surprisingly resilient

Novel sequencing method could be useful for COVID-19 research

Trial shows new first-line treatment option for patients with metastatic kidney cancer

Research identifies new alteration in the brain of people with Alzheimer's

Scientists identify new drug to prevent SARS-CoV-2 infection consequences

Research provides deeper understanding of how neurons in the nose react to odors

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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