T Cell News and Research

Latest T Cell News and Research

Important research on SARS-CoV-2 proteins using proximity labeling

A team of Canadian scientists has recently discovered a wide-range interaction between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and host proteins using proximity-dependent biotinylation approaches.

7 Sep 2020

Polygenic risk score can predict risk of drug-induced liver injury

Scientists who were working on a way to determine the viability of batches of tiny liver organoids have discovered a testing method that may have far broader implications.

7 Sep 2020

A potential new way of treating Alzheimer’s Disease

In this interview, Dr. Brad. L. Heckman speaks to News-Medical about a new pathway that could potentially treat Alzheimers disease.

7 Sep 2020

Novel RNA vaccine from Arcturus Therapeutics protects mice against SARS-CoV-2

A new study published on the preprint server bioRxiv in September 2020 reports a novel RNA vaccine platform that shows robust protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in mice and performs much better than a conventional mRNA vaccine. This could allow single-dose immunization, allowing progress towards global vaccination.

6 Sep 2020

Study shows SARS-CoV-2 cell receptor is a novel target of the gamma-secretase enzyme complex

Based on structural similarities with other targets of the gamma-secretase system, researchers from Columbia University Irving Medical Center in the United States show that the SARS-CoV-2 receptor for cell entry may be affected by its proteolytic activity. Their results are currently freely available in a bioRxiv preprint paper.

6 Sep 2020

Study may provide the basis for better diagnostic, therapeutic approaches to blood diseases

The hemoglobin in the red blood cells ensures that our body cells receive sufficient oxygen. When the blood pigment is broken down, "heme" is produced, which in turn can influence the protein cocktail in the blood.

5 Sep 2020

IU researcher receives NCI grant to study side effects of cancer treatment

A researcher at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center has been awarded a five-year, $5.7 million National Cancer Institute grant to evaluate long-term health outcomes for cancer patients who receive platinum-based chemotherapies.

5 Sep 2020

Fly brain structure governed by lineage-dependent repulsion mechanism between neurons

The brain's structure has columnar features, which are hypothesized to arise from nerve cells (neurons) stemming from the same parent cell, initially forming radial units. How exactly this process unfolds at the molecular level remains unexplained, however.

5 Sep 2020

Maternal dietary imbalance triggers overeating in mice offspring

Pregnant mice fed a diet high in omega-6 fats and low in omega-3 fats produce offspring that go on to exhibit "hedonic"--pleasurable but excessive--levels of consumption of hyper-caloric diets, according to researchers at Hiroshima University.

5 Sep 2020

Early-phase Russian trials reveal safety and immunogenicity of two formulations of a two-part vaccine

Results from two early-phase Russian non-randomised vaccine trials (Sputnik V) in a total of 76 people are published today in The Lancet, finding that two formulations of a two-part vaccine have a good safety profile with no serious adverse events detected over 42 days, and induce antibody responses in all participants within 21 days.

5 Sep 2020

Two researchers from Bielefeld University receive ERC Starting Grants

The European Research Council has awarded ERC Starting Grants to two researchers from Bielefeld University.

5 Sep 2020

Study: Small neutralizing antibody can block SARS-CoV-2 from entering human cells

Researchers at Karolinska Institutet in Sweden have identified a small neutralizing antibody, a so-called nanobody, that has the capacity to block SARS-CoV-2 from entering human cells.

4 Sep 2020

Scientists reconstruct factors involved in the formation of autophagosomes

Autophagy, from the Greek for 'self-eating', is an essential process that isolates and recycles cellular components under conditions of stress or when resources are limited.

4 Sep 2020

Spike-based priming leads to high neutralizing activity in animal models

A new report by researchers at the University of Melbourne and published on the preprint server bioRxiv in September 2020 reports on the use of a two-protein two-dose vaccine regimen and its immunogenicity in two animal models.

4 Sep 2020

High-heat caramelization can increase risk of heart disease, stroke

From MasterChef to MKR, the world's best chefs have taught us how to barbeque, grill and panfry a steak to perfection. But while the experts may be seeking that extra flavour, new research from the University of South Australia suggests high-heat caramelization could be bad for our health.

4 Sep 2020

D614G spike mutation increases infectivity of SARS-CoV-2 and neutralization susceptibility

As the COVID-19 pandemic progresses, it is crucial to track the viral changes in order to link the clinical and epidemiological features of the disease with these mutations. A new study published on the preprint server bioRxiv* in September 2020 reports on a common severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mutation, D614G, and its effects on the virus.

4 Sep 2020

Researchers identify biomarkers associated with bacterial infection mortality

David Gonzalez's "a-ha" moment came when a physician-colleague, George Sakoulas, MD, shared with him one of the biggest problems faced in clinical practice: How long it takes to diagnose a patient.

4 Sep 2020

Researchers develop novel model to study factors that cause type 2 diabetes

Using cells taken from patients with type 2 diabetes and new techniques to convert them into specialized precursors of muscle cells, researchers have developed a novel 'disease-in-a-dish' model to study the basic molecular factors that lead to the development of type 2 diabetes.

4 Sep 2020

CRISPR-based system suppresses genes related to AAV antibody production

Gene therapy generally relies on viruses, such as adeno-associated virus (AAV), to deliver genes into a cell. In the case of CRISPR-based gene therapies, molecular scissors can then snip out a defective gene, add in a missing sequence or enact a temporary change in its expression, but the body's immune response to AAV can thwart the whole endeavor.

4 Sep 2020

New consortium established to study the characteristics of blood cells

What's the risk of different human populations to develop a disease? To find out, a team led by Université de Montréal professor Guillaume Lettre created an international consortium to study the blood of hundreds of thousands of people worldwide.

4 Sep 2020

T Cell News and Research

Latest T Cell News and Research

Important research on SARS-CoV-2 proteins using proximity labeling

Polygenic risk score can predict risk of drug-induced liver injury

A potential new way of treating Alzheimer’s Disease

Novel RNA vaccine from Arcturus Therapeutics protects mice against SARS-CoV-2

Study shows SARS-CoV-2 cell receptor is a novel target of the gamma-secretase enzyme complex

Study may provide the basis for better diagnostic, therapeutic approaches to blood diseases

IU researcher receives NCI grant to study side effects of cancer treatment

Fly brain structure governed by lineage-dependent repulsion mechanism between neurons

Maternal dietary imbalance triggers overeating in mice offspring

Early-phase Russian trials reveal safety and immunogenicity of two formulations of a two-part vaccine

Two researchers from Bielefeld University receive ERC Starting Grants

Study: Small neutralizing antibody can block SARS-CoV-2 from entering human cells

Scientists reconstruct factors involved in the formation of autophagosomes

Spike-based priming leads to high neutralizing activity in animal models

High-heat caramelization can increase risk of heart disease, stroke

D614G spike mutation increases infectivity of SARS-CoV-2 and neutralization susceptibility

Researchers identify biomarkers associated with bacterial infection mortality

Researchers develop novel model to study factors that cause type 2 diabetes

CRISPR-based system suppresses genes related to AAV antibody production

New consortium established to study the characteristics of blood cells

Immunology eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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