T Cell News and Research

Latest T Cell News and Research

Common diabetes drug controls aspects of inflammation in mice

The diabetes drug metformin--derived from a lilac plant that's been used medicinally for more than a thousand years--has been prescribed to hundreds of millions of people worldwide as the frontline treatment for type 2 diabetes.

9 Sep 2020

Scientists shed new light on gene regulatory pathways activated by stress hormone

Scientists have long known that chronic stress experienced early in life, or even chronic prenatal exposure to maternal stress hormones in the womb, can shorten lifespan and contribute to age-related chronic diseases like arthritis, asthma, cancer, cardiovascular disease, diabetes and even mental illness later in life -- long after the source of stress has been removed.

9 Sep 2020

Host gene editing main driving force of SARS-CoV-2 mutations

A new study published on the aRxiv preprint server in September 2020 shows that the host immune response, mediated by two RNA editors, causes the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to adapt and change strain characteristics.

9 Sep 2020

Study shows how inhibitory learning enables memories to be stable over time

In years to come, our personal memories of the COVID-19 pandemic are likely to be etched in our minds with precision and clarity, distinct from other memories of 2020.

9 Sep 2020

Study sheds new light on function and regulation of APOBEC3B in adrenocortical carcinoma

The cover for issue 36 of Oncotarget features, "Knockdown of APOBEC3B is associated with a lower tumor growth in an adrenocortical carcinoma xenograft mouse model," by Gara, et al. which reported that the role of APOBEC3B in adrenocortical carcinoma and the mechanisms through which its expression is regulated in cancer are not fully understood.

9 Sep 2020

New study can advance scientific understanding of the function of astrocytes

New research from Oregon Health & Science University for the first time documents the presence of astrocytes in zebrafish, a milestone that will open new avenues of research into a star-shaped type of glial cell in the brain that is critical for nearly every aspect of brain assembly and function.

9 Sep 2020

Scientists explain why men are at higher risk from COVID-19

Published in the journal PLOS Biology, the study aimed to provide a better understanding of the mechanisms that drive the varying responses of the infected individuals among different patient demographics, including sex and age.

9 Sep 2020

New combination therapy helps fight cancer

Radiation causes key changes to immune cells in kidney cancer tumors.T cells in tumors are expanded in blood shortly after radiation, then decrease.

9 Sep 2020

Researchers discuss the role of chemical senses in disease and social interactions in humans, animals

Across 5 days in August (3rd-7th), scientists from around the world gathered virtually to present and discuss new information on the role of the chemical senses in disease, nutrition, and social interactions in humans and animals.

9 Sep 2020

Vitamin D deficiency can increase risk of COVID-19

Researchers from Israel have found that there could be a link between deficiency of vitamin D and infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Their study titled, “The link between vitamin D deficiency and COVID-19 in a large population,” has been released pre-publication at the medRxiv* server.

8 Sep 2020

New project seeks to understand the origin and role of ecDNA in cancer development

A team of pediatric oncologists led by PD Dr. Anton G. Henssen has set out to further improve our understanding of the mechanisms involved in cancer development and disease progression.

8 Sep 2020

'Molecular brake' on the immune system could be potential treatment target for severe COVID-19

Older people and people with underlying medical conditions are at particular risk of severe COVID-19. A group of researchers from Charité - Universitätsmedizin Berlin have discovered one possible reason for this vulnerability.

8 Sep 2020

Memory B cells indicate durable immunity in COVID-19

Now a new study by researchers at SUNY Upstate Medical University and published recently on the preprint server medRxiv in September 2020 shows that memory B cells are upregulated in convalescent COVID-19 patients, correlating with a better immune response and shorter symptom duration.

8 Sep 2020

Targeted therapy can provide benefits to lung cancer patients with specific gene mutations

A targeted therapy called capmatinib can provide significant benefits to patients who have advanced lung cancer with specific gene mutations, according to recently published results from a phase two clinical trial.

8 Sep 2020

Combination of gas embolization and chemotherapy can lead to complete tumor regression

Hepatocellular carcinoma is a particularly stubborn form of cancer with few treatments and a high mortality rate.

8 Sep 2020

Study reveals complex immunology behind MIS-C in children with COVID-19

In a recent paper published in the prestigious journal Cell, researchers from Sweden and Italy show that inflammatory response in Multisystem Inflammatory Syndrome in Children associated with coronavirus disease (COVID-19) differs from the cytokine storm found in severe acute illness, involving autoantibodies at the same time and sharing several features with Kawasaki disease.

8 Sep 2020

Computer model can replicate the unique firing-rate dependent behavior of Purkinje neurons

Research conducted by the Computational Neuroscience Unit at the Okinawa Institute of Science and Technology Graduate University has shown for the first time that a computer model can replicate and explain a unique property displayed by a crucial brain cell.

8 Sep 2020

The T cell responses in COVID-19 recovered individuals

A recent study demonstrates that functional CD4+ and CD8+ T cells specifically targeting the entire proteome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain active in individuals who have recovered from severe or mild coronavirus disease 2019 (COVID-19). Moreover, the magnitude of T cell response is correlated with the antibody response. The study is published in the journal Nature Immunology.

8 Sep 2020

New findings change the understanding of cholesterol’s effects on cellular membranes

For more than a decade, scientists have accepted that cholesterol - a key component of cell membranes - did not uniformly affect membranes of different types.

8 Sep 2020

Acne drug could be a potential treatment for dilated cardiomyopathy

Dilated cardiomyopathy (DCM) is a leading cause of heart failure, affecting 1 in 250 people. The disease is characterised by an increase in size of the left ventricle of the heart.

8 Sep 2020

T Cell News and Research

Latest T Cell News and Research

Common diabetes drug controls aspects of inflammation in mice

Scientists shed new light on gene regulatory pathways activated by stress hormone

Host gene editing main driving force of SARS-CoV-2 mutations

Study shows how inhibitory learning enables memories to be stable over time

Study sheds new light on function and regulation of APOBEC3B in adrenocortical carcinoma

New study can advance scientific understanding of the function of astrocytes

Scientists explain why men are at higher risk from COVID-19

New combination therapy helps fight cancer

Researchers discuss the role of chemical senses in disease and social interactions in humans, animals

Vitamin D deficiency can increase risk of COVID-19

New project seeks to understand the origin and role of ecDNA in cancer development

'Molecular brake' on the immune system could be potential treatment target for severe COVID-19

Memory B cells indicate durable immunity in COVID-19

Targeted therapy can provide benefits to lung cancer patients with specific gene mutations

Combination of gas embolization and chemotherapy can lead to complete tumor regression

Study reveals complex immunology behind MIS-C in children with COVID-19

Computer model can replicate the unique firing-rate dependent behavior of Purkinje neurons

The T cell responses in COVID-19 recovered individuals

New findings change the understanding of cholesterol’s effects on cellular membranes

Acne drug could be a potential treatment for dilated cardiomyopathy

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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