T Cell News and Research

Latest T Cell News and Research

Study links a specific procedure to pregnancy complications in assisted reproduction

An experimental study from researchers in the Perelman School of Medicine at the University of Pennsylvania links a specific procedure - embryo culture - that is part of the assisted reproduction process (ART) to placental abnormalities, risk for preeclampsia, and abnormal fetal growth.

8 Jun 2020

New EUbOPEN consortium will enable access to research tools to unlock disease biology

Frankfurt and Ingelheim. Almost twenty years after deciphering the human genome, our understanding of human disease is still far from complete.

8 Jun 2020

Virginia Tech researcher develops new ‘fat burning’ molecule with potential to treat obesity

Obesity affects more than 40 percent of adults in the United States and 13 percent of the global population.

8 Jun 2020

Study identifies potential biomarker for prescreening donor's stem cells

A new study released today in STEM CELLS addresses a significant problem that has been confronting human mesenchymal stem cells (hMSCs) therapy.

8 Jun 2020

Study uncovers link between psoriasis and joint disease

A team led by Case Western Reserve University School of Medicine researchers has made two major discoveries involving psoriasis, a chronic and debilitating skin disease with no known cure.

8 Jun 2020

Bioinsider presents "Diagnostic Landscape For COVID19” virtual meeting

Bioinsider LLC (Bioinsider) will present the “Diagnostic Landscape for COVID-19” virtual meeting on Thursday, June 18, 2020.

8 Jun 2020

Researchers identify enzyme essential for intestinal epithelial differentiation

The intestinal epithelium is the inner layer of the intestinal wall, which separates host tissue from the intestinal microbiota.

8 Jun 2020

Researchers discover important molecular mechanism of Charcot-Marie-Tooth disease

Charcot-Marie-Tooth (CMT) disease is the most common form of inherited neuropathies. A genetic mutation causes the insulating myelin layer of peripheral nerves to become progressively damaged, resulting in severe disabilities in the case of CMT type 4B, for instance.

8 Jun 2020

Automated 3D brain imaging data analysis enables precise mapping of complex neural circuits

Automated 3-D brain imaging data analysis technology offers more reliable and standardized analysis of the spatial organization of complex neural circuits.

8 Jun 2020

Monocytes could be critical in dysregulated immunity in COVID-19

A new study by Spanish researchers as part of the GEN-COVID Project, and published on the preprint server medRxiv* in June 2020, suggests that monocytes are primarily involved in triggering the hyperinflammatory immune response that may underlie severe COVID-19 infection.

8 Jun 2020

The receptor binding domain of the SARS-CoV-2

With the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) across most of the world, scientists are working strenuously to find effective therapies or vaccines. Most strategies being worked on at present are targeting viral entry into the host cells, mainly through the interaction of the SARS-CoV-2 S protein with the angiotensin-converting enzyme 2 (ACE2) receptor.

8 Jun 2020

Inhibition of coronavirus spike protein binding to ACE2

A novel coronavirus, CoV-19, and a later phenotype CoV-2 were identified as the primary cause for severe acute respiratory syndrome (SARS CoV-2). The spike (S) protein of CoV-2 is one target for the development of a vaccine to prevent the viral entry into human cells. The inhibition of the direct interaction between ACE2 and the S-protein could provides a suitable strategy to prevent the membrane fusion of CoV-2 and the viral entry into human cells. Using MD simulations, we investigate the assembly process of a Coronavirus Spike protein fragment, the hexapeptide YKYRYL on the ACE2 receptor and its inhibitzory effect on the aggregation and activation of the CoV-2 spike receptor protein at the same receptor protein.

8 Jun 2020

SARS-CoV-2 invasion of central nervous system through olfactory tract

As the COVID-19 pandemic continues to claim lives throughout the world, the evidence is mounting that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the respiratory tract as well as the central nervous system. Now, a new study by German researchers published on the preprint server bioRxiv in June 2020 describes various neurological manifestations of COVID-19, as well as the underlying pathophysiology.

7 Jun 2020

Tocilizumab in COVID-19 patients on mechanical ventilation

Now, a new study by researchers from the University of Michigan and published on the online preprint server medRxiv* in June 2020 shows that the cytokine inhibitor tocilizumab could have a favorable effect on survival in the most severely infected patients who require mechanical ventilation. This needs to be confirmed by clinical trials.

7 Jun 2020

New strategy may facilitate development of multi-epitope peptide vaccine against SARS-CoV-2

By combining T and B lymphocyte analysis with manufacturability heuristic, researchers from the US and Germany proposed a set of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine peptides to use in subsequent animal studies and clinical trials. Their paper is currently available on the bioRxiv preprint server.

7 Jun 2020

Kidney enzyme renalase a potential therapy for severe COVID-19

Researchers from Yale School of Medicine have discovered that a low blood level of an enzyme called renalase is associated with severe coronavirus disease 2019 (COVID-19).

7 Jun 2020

Zinc-finger antiviral protein makes SARS-CoV-2 highly susceptible to interferons

By looking into zinc-finger antiviral proteins (ZAP), a new study from Germany and the United Kingdom (UK) and available on the preprint server bioRxiv suggests that zoonotic transmission of a coronavirus with a specific genetic make-up facilitated the pandemic spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but also its sensitivity to interferons.

7 Jun 2020

Using microorganisms and their enzymes to produce minor ginsenosides

In this review article the author Almando Geraldi from the Universitas Airlangga, Indonesia considers the advances in the production of minor ginsenosides using microorganisms and their enzymes.

5 Jun 2020

Approved drug could help dampen massive immune response associated with severe COVID-19

The drug acalabrutinib, FDA-approved for the treatment of several types of B cell cancers, improved the oxygenation levels and decreased molecular markers of inflammation in a majority of 19 patients hospitalized for the treatment of severe COVID-19, according to a new study by Mark Roschewski and colleagues.

5 Jun 2020

MUSC receives $16.5 million NIH funding to open two new digestive disease research centers

This spring marked a seismic shift for digestive and liver disease research at the Medical University of South Carolina with the award of more than $16.5 million in National Institutes of Health funding to open two new tightly integrated centers.

5 Jun 2020

T Cell News and Research

Latest T Cell News and Research

Study links a specific procedure to pregnancy complications in assisted reproduction

New EUbOPEN consortium will enable access to research tools to unlock disease biology

Virginia Tech researcher develops new ‘fat burning’ molecule with potential to treat obesity

Study identifies potential biomarker for prescreening donor's stem cells

Study uncovers link between psoriasis and joint disease

Bioinsider presents "Diagnostic Landscape For COVID19” virtual meeting

Researchers identify enzyme essential for intestinal epithelial differentiation

Researchers discover important molecular mechanism of Charcot-Marie-Tooth disease

Automated 3D brain imaging data analysis enables precise mapping of complex neural circuits

Monocytes could be critical in dysregulated immunity in COVID-19

The receptor binding domain of the SARS-CoV-2

Inhibition of coronavirus spike protein binding to ACE2

SARS-CoV-2 invasion of central nervous system through olfactory tract

Tocilizumab in COVID-19 patients on mechanical ventilation

New strategy may facilitate development of multi-epitope peptide vaccine against SARS-CoV-2

Kidney enzyme renalase a potential therapy for severe COVID-19

Zinc-finger antiviral protein makes SARS-CoV-2 highly susceptible to interferons

Using microorganisms and their enzymes to produce minor ginsenosides

Approved drug could help dampen massive immune response associated with severe COVID-19

MUSC receives $16.5 million NIH funding to open two new digestive disease research centers

Immunology eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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