T Cell News and Research

Latest T Cell News and Research

Researchers design developmental map of sound-sensing structure in mice’s inner ear

A team of researchers has generated a developmental map of a key sound-sensing structure in the mouse inner ear.

30 May 2020

Newer treatment approaches may reduce risk of therapy-related hematologic cancers

While breakthrough treatments have emerged for several cancers over the last two decades, driving striking improvements in survival and other clinical outcomes, too little is known about the risk of therapy-related hematologic cancers following targeted and immunotherapeutic approaches.

29 May 2020

Adoptive T-cell therapy targeting MAGE-A4 achieves responses in patients with multiple solid tumors

The adoptive T-cell therapy ADP-A2M4, which is engineered to express a T-cell receptor (TCR) directed against the MAGE-A4 cancer antigen, achieved responses in patients with multiple solid tumor types, including synovial sarcoma, head and neck cancer and lung cancer, according to results from a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

29 May 2020

Targeted therapy tepotinib shows durable response in NSCLC patients with METex14 skipping mutation

Patients with advanced non-small cell lung cancer (NSCLC) and the MET exon 14 (METex14) skipping mutation had a 46.5% objective response rate to the targeted therapy drug tepotinib, as shown in a study published today in the New England Journal of Medicine and presented at the 2020 American Society of Clinical Oncology Annual Meeting ASCO20 Virtual Meeting (Abstract 9556 - Poster 322) by researchers from The University of Texas MD Anderson Cancer Center.

29 May 2020

Targeted therapy pralsetinib shows high response rates in patients with RET fusion-positive cancers

The targeted therapy pralsetinib appears to have high response rates and durable activity in patients with a broad variety of tumors harboring RET gene fusions, according to results from the international Phase I/II ARROW trial, led by researchers at The University of Texas MD Anderson Cancer Center.

29 May 2020

NIH funding supports research on first therapeutic drug to regenerate heart tissue

With funding from the National Institutes of Health, University of Arkansas researchers hope to develop the first therapeutic drug that can regenerate heart tissue.

29 May 2020

Researchers test new treatment protocol for lymphoma

Lymphoma is a type of blood cancer that develops from lymphocytes (a type of white blood cell). It has many subtypes.

29 May 2020

Blood test offers new opportunities to improve malarial control and elimination strategies

Plasmodium vivax is the most widespread malaria parasite worldwide, with up to two billion people at risk of infection.

29 May 2020

Study: Glucocorticoids are harmful for patients suffering from viral respiratory infections

Glucocorticoids are widely used in treating acute respiratory distress syndrome (ARDS) despite there being no indisputable scientific evidence of their effectiveness.

29 May 2020

New tool may predict best treatment for multiple myeloma

In 1844, multiple myeloma was first treated with a rhubarb pill and an infusion of orange peel. Since then, more than 15 drugs have earned FDA approval to treat multiple myeloma and with so many options, a major question has become what cocktail and sequence is best?

29 May 2020

Scientist explore potential drugs to prevent cell resistance in different types of cancer

Cancer therapy may shrink the tumor of a patient, and the patient may feel better. But unseen on a CT scan or MR image, some of the cells are undergoing ominous changes.

29 May 2020

Combination therapy does not show superior efficacy in newly diagnosed myeloma

The combination of carfilzomib, lenalidomide, and dexamethasone (KRd) did not show superior efficacy in patients with newly diagnosed myeloma absent a high-risk disease prognosis, compared with the standard of care--bortezomib, lenalidomide, and dexamethasone (VRd).

29 May 2020

Study sheds light on homologous recombination of DNA strands

As chromosomes go, X and Y make an unlikely pair. The X is large and contains thousands of genes critical for life. The Y, by contrast, is little more than a nub.

29 May 2020

Targeted therapy shows immense benefit for patients with early stage NSCLC

According to findings led by researchers at Yale Cancer Center, treatment with the targeted therapy osimertinib following surgery significantly improves disease-free survival (DFS) in patients with early-stage, non-small cell lung cancer (NSCLC) with EGFR gene mutations.

29 May 2020

Rare deadly disease linked to coronavirus infection seen in children

Now, new evidence has shown that children with coronavirus disease (COVID-19) experience a Kawasaki-like illness, called multisystem inflammatory syndrome in children (MIS-C). The complication is akin to toxic shock syndrome, a condition that occurs due to sepsis. Though rare, the condition is life-threatening.

29 May 2020

How comorbidities affect SARS-CoV-2 viral entry

Almost from the start of the current COVID-19 pandemic, it has become clear that individuals suffering from other medical conditions like diabetes, cardiovascular disease, and lung disease are far more likely to contract the infection and to have a poorer outcome.

28 May 2020

Biophysicists reveal molecular mechanism behind light-driven sodium pumping

An international research team has for the first time obtained the structure of the light-sensitive sodium-pumping KR2 protein in its active state.

28 May 2020

Stem cell treatments elicit full structural regeneration of the sun-aged skin

For a while now, some plastic surgeons have been using stem cells to treat aging, sun-damaged skin. But while they've been getting good results, it's been unclear exactly how these treatments - using adult stem cells harvested from the patient's own body - work to rejuvenate "photoaged" facial skin.

28 May 2020

Examining the envelope protein of SARS-CoV-2

A new study by researchers at the University of Valencia and published on the preprint online server bioRxiv in May 2020 reports the topology of the envelope protein of the virus, which could contribute to a better understanding of how the virus interacts with other cell components and hopefully help to fight the disease better.

28 May 2020

Ludwig Cancer Research study profiles immune landscape of brain tumors

A Ludwig Cancer Research study has profiled, in a sweeping comparative analysis, the distinct immune landscapes of tumors that arise in the brain, or gliomas, and those that metastasize to the organ from the lungs, breast and skin.

28 May 2020

T Cell News and Research

Latest T Cell News and Research

Researchers design developmental map of sound-sensing structure in mice’s inner ear

Newer treatment approaches may reduce risk of therapy-related hematologic cancers

Adoptive T-cell therapy targeting MAGE-A4 achieves responses in patients with multiple solid tumors

Targeted therapy tepotinib shows durable response in NSCLC patients with METex14 skipping mutation

Targeted therapy pralsetinib shows high response rates in patients with RET fusion-positive cancers

NIH funding supports research on first therapeutic drug to regenerate heart tissue

Researchers test new treatment protocol for lymphoma

Blood test offers new opportunities to improve malarial control and elimination strategies

Study: Glucocorticoids are harmful for patients suffering from viral respiratory infections

New tool may predict best treatment for multiple myeloma

Scientist explore potential drugs to prevent cell resistance in different types of cancer

Combination therapy does not show superior efficacy in newly diagnosed myeloma

Study sheds light on homologous recombination of DNA strands

Targeted therapy shows immense benefit for patients with early stage NSCLC

Rare deadly disease linked to coronavirus infection seen in children

How comorbidities affect SARS-CoV-2 viral entry

Biophysicists reveal molecular mechanism behind light-driven sodium pumping

Stem cell treatments elicit full structural regeneration of the sun-aged skin

Examining the envelope protein of SARS-CoV-2

Ludwig Cancer Research study profiles immune landscape of brain tumors

Immunology eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

Newsletters you may be interested in