T Cell News and Research

Latest T Cell News and Research

Nanoscope received NIH grant to advance ultrafast laser-based gene delivery to the retina

The Nanoscope team has developed Multi-Characteristic Opsins to sensitize cells toward low level of white light so that vision is improved at ambient room light.

28 May 2020

Combination therapy found to be effective against IDH1-mutated acute myeloid leukemia

A combination therapy of ivosenidib (IVO) plus venetoclax (VEN) with or without azacitidine (AZA) was found to be effective against a specific genetic subtype of acute myeloid leukemia (AML) in a Phase Ib/II trial led by researchers at The University of Texas MD Anderson Cancer Center.

28 May 2020

Study provides groundwork for restoring nerve-muscle connection in ALS

Patients with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, lose muscle control as nerve cells or neurons in the brain and spinal cord degenerate and can no longer send signals to muscles.

28 May 2020

Scientists from gnomAD Consortium release first set of discoveries on human genetic variation

For the last eight years, the Genome Aggregation Database Consortium (and its predecessor, the Exome Aggregation Consortium, or ExAC), has been working with geneticists around the world to compile and study more than 125,000 exomes and 15,000 whole genomes from populations around the world.

28 May 2020

Ferritin heavy chain protein shows promise as a potential SARS-CoV-2 vaccine or antiviral

A new study published on the online preprint server bioRxiv in May 2020 reports the construction and testing of a new ferritin-based antigen-bearing protein that has biological activity towards the ACE2 receptor. This could indicate its potential for development as a vaccine or antiviral.

28 May 2020

Pitt researcher to explore the neurological sex-based divide in dementia

Fifty million people worldwide are living with dementia, a broad term for diseases and conditions characterized by progressive cognitive decline.

28 May 2020

Researchers grow lung organoids from stem cells for Sars-Cov-2 research

A Bochum-based team intends to use organoids from stem cells to study the progression of Sars-CoV-2 infection and to identify antiviral substances.

28 May 2020

A closer look at TMPRSS2: This could help treat COVID-19

The transmembrane protease serine-type 2 (TMPRSS2) protein plays a key role in COVID-19 infection since it primes the viral spike protein to allow viral entry into the target cell. A new study by researchers at Imperial College London and published on the preprint server bioRxiv in May 2020 describes the protein, which could be an attractive drug target to help manage COVID-19.

28 May 2020

Inhibiting tumor signals can suppress the spread of cancer

For most people who die of cancer, the spread of the initial tumor is to blame. "Metastasis is what kills most cancer patients," says Serge Fuchs, a professor in Penn's School of Veterinary Medicine.

28 May 2020

CBD treatment improves arthritis symptoms in dogs, study finds

A team led by researchers at Baylor College of Medicine in collaboration with Medterra CBD conducted the first scientific studies to assess the potential therapeutic effects of cannabidiol for arthritic pain in dogs, and the results could lead the way to studying its effect in humans.

28 May 2020

Using electric current to directly control gene expression

A team of researchers led by ETH professor Martin Fussenegger has succeeded in using an electric current to directly control gene expression for the first time.

28 May 2020

Research provides important insights into genetic adaptation of SARS-CoV-2 to humans

In their groundbreaking paper available on the preprint server medRxiv, University of Pittsburgh researchers were appraising signals of SARS-CoV-2 genome evolution and found that purifying selection (i.e., removal of deleterious mutations) represents the dominant trait during early coronavirus disease (COVID-19) pandemic - suggesting that the virus will evolve as it diversifies in a growing number of hosts.

28 May 2020

Characterizing immune cells in malignant brain tumors

It is not always possible to completely remove malignant brain tumors by surgery so that further treatment is necessary.

28 May 2020

New drug combinations could help overcome genetic immunotherapy resistance

A new study from researchers at the UCLA Jonsson Comprehensive Cancer Center helps explain how disruptions in genes can lead to the resistance to one of the leading immunotherapies, PD-1 blockade, and how new drug combinations could help overcome resistance to the anti-PD-1 therapy in a mechanistically-based way.

28 May 2020

Scientists create adenovirus that kills cancer cells

An adenovirus is now better able to target and kill cancer cells due to the addition of an RNA stabilizing element.

28 May 2020

Clinical study shows promising results for treatment of VHL disease-associated renal tumors

In an international trial led by researchers at The University of Texas MD Anderson Cancer Center, treatment with MK-6482, the small molecule inhibitor of hypoxia-inducible factor (HIF)-2a was well tolerated and resulted in clinical responses for patients with von Hippel-Lindau disease (VHL)–associated renal cell carcinoma.

28 May 2020

PKU-led team identifies potent neutralizing antibodies against SARS-CoV-2

A joint research team led by Sunney Xie, Director of Beijing Advanced Innovation Center for Genomics at Peking University has successfully identified multiple highly potent neutralizing antibodies against the novel coronavirus SARS-CoV-2, the causative virus of the respiratory disease COVID-19, from convalescent plasma by high-throughput single-cell sequencing.

28 May 2020

T Cell News and Research

Latest T Cell News and Research

Nanoscope received NIH grant to advance ultrafast laser-based gene delivery to the retina

Combination therapy found to be effective against IDH1-mutated acute myeloid leukemia

Study provides groundwork for restoring nerve-muscle connection in ALS

Scientists from gnomAD Consortium release first set of discoveries on human genetic variation

Ferritin heavy chain protein shows promise as a potential SARS-CoV-2 vaccine or antiviral

Pitt researcher to explore the neurological sex-based divide in dementia

Researchers grow lung organoids from stem cells for Sars-Cov-2 research

A closer look at TMPRSS2: This could help treat COVID-19

Inhibiting tumor signals can suppress the spread of cancer

CBD treatment improves arthritis symptoms in dogs, study finds

Using electric current to directly control gene expression

Research provides important insights into genetic adaptation of SARS-CoV-2 to humans

Characterizing immune cells in malignant brain tumors

New drug combinations could help overcome genetic immunotherapy resistance

Scientists create adenovirus that kills cancer cells

Clinical study shows promising results for treatment of VHL disease-associated renal tumors

PKU-led team identifies potent neutralizing antibodies against SARS-CoV-2

New insight into RNA movements can pave way for strategies to treat cancer

CytoSMART Technologies launches new live-cell imaging system

SCN study outlines impacts of targeted skills training on Canada’s regenerative medicine sector

Immunology eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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