T Cell News and Research

Latest T Cell News and Research

Catastrophic macropinocytosis may aid in cancer treatment

In laboratory experiments, a metabolic inhibitor was able to kill a variety of human cancer cells of the skin, breast, lung, cervix and soft tissues through a non-apoptotic route -- catastrophic macropinocytosis.

18 Dec 2019

Scientists use supercomputers to shed light on skin cancer formation mechanism

Skin cancer, particularly melanoma, which is the deadliest and most serious type of human skin cancer, begins as a small lesion or blemish. Usually, these blemishes start off as harmless accumulation of melanocytes, which give the skin its color. As the disease progresses, it can spread throughout the body.

18 Dec 2019

Blue light may not be so bad for sleep

The sun provides warmth and a bright light with orange-yellow hues during the day. But at night, cold, dim, and white light from the Moon, which exposes people to light similar to blue wavelengths emitted by various types of artificial lighting. Previously, blue light has been dubbed as disruptive to a good night’s sleep.

18 Dec 2019

Study opens up new treatment possibilities for Wilms' tumor

As an embryo develops, its cells must learn what to do with the thousands of genes they've been equipped with. That's why each cell comes with a detailed gene-expression manual outlining exactly which genes should be switched on, to what extent, and when.

18 Dec 2019

Research shows harmful effects of chemicals in vaping liquids to lung tissue

New research appearing in the journal Scientific Reports unpacks the list of chemicals that comprise flavored e-liquids and pods used in vaping and details their harmful effects to lung tissue, including inflammation and genetic damage that could indicate long-term risk for respiratory disease and even cancer.

18 Dec 2019

Scientists explore role of IgG4 Abs in IgG4-related disease

Autoimmune diseases are a medical conundrum. In people with these conditions, the immune system of the body, the designated defense system, starts attacking the cells or organs of its own body, mistaking the self-cells for invading disease-causing cells. Often, the cause for this spontaneous dysfunction is not clear, and hence, treatment of these diseases presents a major and ongoing challenge.

18 Dec 2019

Different mutations in a single gene can have myriad effects on a person's health

Mount Sinai researchers have found that different mutations in a single gene can have myriad effects on a person's health, suggesting that gene therapies may need to do more than just replenish the missing or dysfunctional protein the gene is supposed to encode, according to a study published in Nature Genetics in November.

18 Dec 2019

Clinical study demonstrates effective alternative to mastectomy for recurrent breast cancer

Mastectomy has historically been the standard treatment for breast cancer patients experiencing recurrence after an initial lumpectomy and whole-breast radiation. Now, a phase 2 clinical trial led by Douglas W. Arthur, M.D., chair and professor in the Department of Radiation Oncology at VCU Massey Cancer Center and VCU School of Medicine, has demonstrated an effective alternative.

18 Dec 2019

IU scientists discover that beta-carophyllene improves wound healing

Indiana University researchers have discovered that a chemical compound found in essential oils improves the healing process in mice when it is topically applied to a skin wound -- a finding that could lead to improved treatments for skin injuries in humans.

18 Dec 2019

Aarhus University professor receives grant to develop a new form of cell therapy

Associate Professor Menglin Chen has received a major grant from the Carlsberg Foundation to develop a completely new method of regenerating brain and heart cells.

18 Dec 2019

Researchers discover new way to supercharge protein production

Medicines such as insulin for diabetes and clotting factors for hemophilia are hard to synthesize in the lab. Such drugs are based on therapeutic proteins, so scientists have engineered bacteria into tiny protein-making factories.

18 Dec 2019

Yale researchers identify cellular chicanery that jumpstarts cancer

The progression of cancer has been studied extensively, and the key steps in this journey have been well mapped, at least in some solid tumors: Lesions to genes that confer risk of cancer accumulate and alter normal cell behaviors, giving rise, scientists believe, to early stage cancer cells that eventually swamp normal cells and become deadly.

18 Dec 2019

Scientists use blue mushroom dye to develop fluorescent tool for detecting reactive oxygen species

A new fluorescent tool for detecting reactive oxygen species based on a chemical found in mushrooms has been developed by scientists at the University of Bath.

17 Dec 2019

Radiation-induced brain damage: new study reveals the mechanism

Following radiation therapy to the head for brain tumors, more than 80% of patients who live six months at least after the treatment report a loss of some cognitive functions such as memory, thinking and related tasks. Now a new study published in the journal Scientific Reports shows why this happens, which in turn could pave the way to correct this damage and protect the brain in future patients.

17 Dec 2019

Nature’s own gene therapy

A brand-new technique of gene therapy was reported on December 16, 2019, in the journal Nature Biomedical Engineering. The scientists made use of the potential of human cells to produce biological nanoparticles chockful of edited genes, so that they could insert beneficial genes into people suffering from various disease processes.

17 Dec 2019

Using math equations to detect and forecast liver cancer risk

The use of mathematical modeling in the study of biological systems has become a challenging and rewarding field of research as it yields many unknown pieces of information. A new study published online on December 16, 2019, in the journal Proceedings of the National Academy of Science (PNAS).

17 Dec 2019

Moffitt researchers develop efficient method for creating mouse models to study melanoma

Genetically engineered mouse models are often used by scientists to study how the addition, deletion or mutation of genes affects the development of disease and effects of drugs.

17 Dec 2019

Leukemia patients treated with common cancer drug have heightened risk of heart failure

Patients with acute lymphoblastic leukemia or acute myeloid leukemia who are treated with anthracyclines are at a heightened risk of heart failure- most often within one year of exposure to the chemotherapy treatment, according to a new study led by researchers at Penn Medicine.

17 Dec 2019

Brazilian researchers create hepatic organoids by 3D bioprinting

Using human blood cells, Brazilian researchers have succeeded in obtaining hepatic organoids ("mini-livers") that perform all of the liver's typical functions, such as producing vital proteins, storing vitamins, and secreting bile, among many others.

17 Dec 2019

Immune cells may link body composition to how cognition changes with age, study suggests

Iowa State researchers have found for the first time that less muscle and more body fat may affect our thinking as we age, and changes in parts of the immune system could be responsible.

17 Dec 2019

T Cell News and Research

Latest T Cell News and Research

Catastrophic macropinocytosis may aid in cancer treatment

Scientists use supercomputers to shed light on skin cancer formation mechanism

Blue light may not be so bad for sleep

Study opens up new treatment possibilities for Wilms' tumor

Research shows harmful effects of chemicals in vaping liquids to lung tissue

Scientists explore role of IgG4 Abs in IgG4-related disease

Different mutations in a single gene can have myriad effects on a person's health

Clinical study demonstrates effective alternative to mastectomy for recurrent breast cancer

IU scientists discover that beta-carophyllene improves wound healing

Aarhus University professor receives grant to develop a new form of cell therapy

Researchers discover new way to supercharge protein production

Yale researchers identify cellular chicanery that jumpstarts cancer

Scientists use blue mushroom dye to develop fluorescent tool for detecting reactive oxygen species

Radiation-induced brain damage: new study reveals the mechanism

Nature’s own gene therapy

Using math equations to detect and forecast liver cancer risk

Moffitt researchers develop efficient method for creating mouse models to study melanoma

Leukemia patients treated with common cancer drug have heightened risk of heart failure

Brazilian researchers create hepatic organoids by 3D bioprinting

Immune cells may link body composition to how cognition changes with age, study suggests

Immunology eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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