T Cell News and Research

Latest T Cell News and Research

Important opportunity to act on gaps and challenges in seasonal influenza outbreaks

Today's subcommittee hearing on U.S. preparedness and responses for the 2019-2020 flu season offers an important opportunity to examine and act on gaps and challenges exacerbating the public health threats of seasonal influenza outbreaks.

5 Dec 2019

New model can help study the mechanisms of bone metastasis, tumor immune response

The Research Team reports the establishment of B6Ca P, an allograft tumor line from a Hi-Myc transgenic mouse that had been backcrossed onto C57BL/6J background.

4 Dec 2019

Molecular makeup of abnormal proteins in brain diseases shows structural diversity

Parkinson's and multisystem atrophy - both of them neurodegenerative diseases - are associated with the accumulation of alpha-synuclein proteins in the brain.

4 Dec 2019

ADDF announces new awards through its Diagnostics Accelerator initiative

The Alzheimer's Drug Discovery Foundation announced six new investments totaling $6 million through its Diagnostics Accelerator initiative.

4 Dec 2019

Host cell calpain proteases can process enterovirus polyprotein in vitro, study shows

It has long been suggested that a cell protease could take part in enterovirus infection. However, the identity of such proteases have remained unknown.

4 Dec 2019

Transitional T cells could help improve cancer immunotherapy

In chronic viral infections and cancer, T cell dysfunction is sure to be observed. A new study to be published in the journal Immunity shows that before these cells are completely exhausted, there is a transitory stage in which some cells are present with features that are characteristic of neither the stem-like T cells nor the mature but exhausted T cells.

4 Dec 2019

New method for discovering potential cancer-treating compounds

A new study published in the journal Cell Reports reports a novel method by which antitumor drugs that focus on reawakening exhausted immune cells called cytotoxic T cells against cancer can be quickly identified. This could help treat a large subset of cancers that thrive because of their ability to suppress antitumor activity in T cells.

4 Dec 2019

Gabapentin – a drug for nerve pain could help patients with spinal injury finds study

A preclinical study with mice has shown that Gabapentin, a drug that is commonly used in nerve pain could be useful for patients with spinal cord injury. Use of the drug showed improvement in upper limb function among the mice models of spinal cord injury, wrote the researchers. The study titled, “Gabapentinoid treatment promotes corticospinal plasticity and regeneration following murine spinal cord injury,” was published this week in the latest issue of the Journal of Clinical Investigation.

4 Dec 2019

Scientists create artificial neurons that help cure chronic diseases

Artificial brain cells could now be implanted in the brain to repair the damage caused by chronic diseases, such as Alzheimer’s disease and other neurodegenerative conditions, thanks to a team of scientists who created bionic neurons that work like the real thing.

4 Dec 2019

Experts at AGS-NIA U13 conference provide insights on bone and soft-tissue disorders

Experts at a prestigious medical conference hosted by the American Geriatrics Society and funded by the National Institutes of Health's National Institute on Aging hope their work--reported this week in the Journal of the American Geriatrics Society--can help yield hard evidence to address the range of "soft tissue" and bone disorders that contribute to falls, fractures, and muscle loss as we age.

4 Dec 2019

A major step toward preventing GvHD in patients receiving bone marrow transplants

A drug used for rheumatoid arthritis has moved a step closer to FDA approval for a desperately needed new use.

4 Dec 2019

Baylor researchers report creation of an 'epigenetic couch potato' mouse

Why is it that some people love to exercise, and others hate it? Most people would assume it's all due to genetics, but a new Baylor College of Medicine led study in mice shows for the first time that a different molecular level of regulation - epigenetics - plays a key role in determining one's innate drive to exercise.

4 Dec 2019

Early adherence step in intestinal transit of Shigella discovered

The bacterial pathogen Shigella, often spread through contaminated food or water, is a leading cause of mortality in both children and older adults in the developing world.

4 Dec 2019

The 2019 ACR/EULAR Classification Criteria for IgG4-Related Disease released

The American College of Rheumatology and the European League Against Rheumatism released the 2019 ACR/EULAR Classification Criteria for IgG4-Related Disease. It is the first criteria developed specifically for this recently recognized disease.

4 Dec 2019

FDA-approved drug repairs gut leakiness associated with ulcerative colitis

A research team led by biomedical scientists at the University of California, Riverside, has found that a drug approved by the FDA to treat rheumatoid arthritis and ulcerative colitis can repair permeability defects in the gut's epithelium.

4 Dec 2019

Cleveland Clinic to study ecological, evolutionary mechanisms that contribute to lung cancer

Jacob Scott, M.D., Ph.D., a physician researcher from Cleveland Clinic's Department of Translational Hematology and Oncology Research, recently received a $2.8 million grant from the National Cancer Institute, part of the National Institutes of Health, to study how ecological and evolutionary mechanisms contribute to lung cancer development and progression, and how the interplay between these mechanisms may provide novel treatment insights.

4 Dec 2019

Ground breaking discovery could lead to new anti TB drugs

New drugs to treat strains of TB which have become resistant to treatment are now a possibility following a ground breaking discovery from the University of Surrey.

4 Dec 2019

Newly developed cell models can open up new avenues for ocular drug discovery

Researchers at the University of Eastern Finland have developed two new cell models that can open up new avenues for ocular drug discovery. The new cell models are continuously growing retinal pigment epithelial cells, which have many benefits over the models currently used by researchers and pharmaceutical companies. The models were developed by Professor Arto Urtti's Ocular Drug Delivery group at the University of Eastern Finland.

4 Dec 2019

Researchers create 3D liver model for improved diagnosis of non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease is becoming the most common chronic liver disorder in developed countries. Histological analysis of liver tissue is the only widely accepted test for diagnosing and distinguishing different stages of the disease. However, this technique provides only two-dimensional images of the liver tissue in low resolution and overlooks potentially important 3D structural changes.

4 Dec 2019

One-third of lung cancer patients have depression symptoms, study finds

About one-third of patients newly diagnosed with the most common form of lung cancer have moderate to severe symptoms of depression, a new study suggests.

4 Dec 2019

T Cell News and Research

Latest T Cell News and Research

Important opportunity to act on gaps and challenges in seasonal influenza outbreaks

New model can help study the mechanisms of bone metastasis, tumor immune response

Molecular makeup of abnormal proteins in brain diseases shows structural diversity

ADDF announces new awards through its Diagnostics Accelerator initiative

Host cell calpain proteases can process enterovirus polyprotein in vitro, study shows

Transitional T cells could help improve cancer immunotherapy

New method for discovering potential cancer-treating compounds

Gabapentin – a drug for nerve pain could help patients with spinal injury finds study

Scientists create artificial neurons that help cure chronic diseases

Experts at AGS-NIA U13 conference provide insights on bone and soft-tissue disorders

A major step toward preventing GvHD in patients receiving bone marrow transplants

Baylor researchers report creation of an 'epigenetic couch potato' mouse

Early adherence step in intestinal transit of Shigella discovered

The 2019 ACR/EULAR Classification Criteria for IgG4-Related Disease released

FDA-approved drug repairs gut leakiness associated with ulcerative colitis

Cleveland Clinic to study ecological, evolutionary mechanisms that contribute to lung cancer

Ground breaking discovery could lead to new anti TB drugs

Newly developed cell models can open up new avenues for ocular drug discovery

Researchers create 3D liver model for improved diagnosis of non-alcoholic fatty liver disease

One-third of lung cancer patients have depression symptoms, study finds

Immunology eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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