T Cell News and Research

Latest T Cell News and Research

Isolated components of Saussurea have positive effect on bone tissue regeneration

Saussurea controversa is a perennial herbaceous plant that has been traditionally used by the people of the Far East, Siberia, Tibet, and Mongolia to treat liver, kidney, digestive tract, and locomotive diseases. Its dried leaves are sold in pharmacies because their decoction is widely used as a medicine against cold and bronchitis. To understand what substances this plant owes its medicinal properties to, a team of scientists from Siberian State Medical University and Tomsk Polytechnic University extracted individual components from the plant and determined their composition.

3 Dec 2019

New human colon-on-a-chip enables in vitro study of mucus physiology

We have a mutualistic but complicated relationship with the collection of microbes in our gut known as the intestinal microbiome.

3 Dec 2019

New treatment approach could improve outcomes for people with cystic fibrosis

A new approach to treating people with cystic fibrosis (CF) has been shown to reduce inflammation, which has the potential to reduce the need for lung transplants and lower the risk of death.

3 Dec 2019

Spinal implants could one day restore the ability to stand, walk in patients with paralysis

When Vivian Mushahwar first applied to grad school, she wrote about her idea to fix paralysis by rewiring the spinal cord.

3 Dec 2019

Multiple mechanisms at work in diabetes drug metformin

Metformin is the most commonly prescribed type 2 diabetes drug, yet scientists still do not fully know how it works to control blood sugar levels. In a collaborative effort, researchers from the Salk Institute, The Scripps Research Institute and Weill Cornell Medical College have used a novel technology to investigate why it functions so well.

3 Dec 2019

Roswell Park-led scientists identify new defense mechanism against prostate cancer

A research team led by a scientist at Roswell Park Comprehensive Cancer Center has identified the molecule LRIG1 as an important endogenous tumor suppressor in prostate cancer. Writing in the journal Nature Communications, the team documents their findings from preclinical studies showing that overexpression of the LRIG1 protein inhibits prostate cancer development, while reducing naturally occurring LRIG1 promotes prostate tumor development.

3 Dec 2019

Freiburg scientists decipher basic molecular control mechanisms behind cellular identity

A research team headed by Prof. Dr. Sebastian Arnold and Jelena Tosic from the Faculty of Medicine at the University of Freiburg has now succeeded in deciphering basic molecular control mechanisms by which stem cells decide which embryonic cell types to turn into.

3 Dec 2019

Researchers show how the ductal system connecting digestive organs is formed

A specialized system of ducts transports bile and enzymes from the liver and pancreas to the intestine. In a new study, researchers from the University of Copenhagen have shown how this ductal system is formed. The new knowledge can help understanding how congenital diseases in that part of the body arise.

3 Dec 2019

Novel remote-controlled 'smart' platform aids in treatment of cardiovascular disease

According to the World Health Organization, cardiovascular disease has become the leading cause of death worldwide. However, vascular regeneration is a promising treatment for cardiovascular disease. Remodeling the endothelium - i.e., forming a confluent vascular endothelial cell monolayer on the lumen - plays a vital role in this process.

3 Dec 2019

Study finds it may be possible to treat endometriosis using an investigational cancer drug

Researchers have shown that painful endometriosis symptoms could be alleviated using an investigational cancer drug.

3 Dec 2019

Inhibition of a protease could improve the treatment of IBD, study shows

Scientists at the Centro Nacional de Investigaciones Cardiovasculares and the Centro de Investigaciones Biológicas of the Consejo Superior de Investigaciones Científicas have identified the protease MT1-MMP as a possible future target for drugs to treat inflammatory bowel disease.

3 Dec 2019

Streamlining Immuno-Oncological Therapeutic Antibody Discovery

The growing trend of implementing immunotherapy into oncology has resulted in various new therapeutic cancer treatments utilizing antibodies.

From Sartorius 3 Dec 2019

Study: Calcium signaling can help address drug resistance to non-Hodgkin lymphoma

Gene expression profiling and other analyses conducted by Rutgers Cancer Institute of New Jersey researchers and colleagues examining drug resistance to a common antibody therapy for non-Hodgkin lymphoma have identified calcium signaling as a novel and exploitable target in overcoming this treatment obstacle.

3 Dec 2019

Study: TBK1 protein promotes cancer development, suppresses immune response to the disease

Researchers at The University of Texas MD Anderson Cancer Center have found that a protein involved in immune response to microbes also can fuel cancer development and suppress immune response to the disease.

3 Dec 2019

Study: Spleen and gut lymph nodes may serve as reservoir replication sites for HIV virus

An international team led by Professor Jerome Estaquier from Universite Laval's Faculty of Medicine and the CHU de Quebec-Universite Laval Research Center may have discovered where in the body HIV takes refuge during antiretroviral treatment.

3 Dec 2019

New computational method can help predict and design allosteric functions in proteins

Called the "second secret of life", allostery is one of the most fundamental processes of biology and has been a central focus among scientists across the life sciences spectrum, from fundamental biology to drug development.

3 Dec 2019

Discovery could offer insight into different risk of diseases in African Americans

The percentage of African ancestry in a person's genome determines the level that certain genes are expressed, called mRNA, according to a new Northwestern Medicine study.

3 Dec 2019

Key component of immune response is activated by short RNAs, shows study

Ludwig-Maximilians-Universitaet (LMU) in Munich researchers report that a central component of the innate immune response is activated by two short RNAs which are produced by site-specific cleavage of a precursor RNA molecule - and both derivatives are generated by the same enzyme.

3 Dec 2019

New findings regarding maintenance and functioning of the endosome

On a daily basis, multitudes of molecules enter each cell in our body. These can be nutrients or signal molecules or pathogenic microorganisms. An organelle in the cell directs these molecules to other stations for further processing.

3 Dec 2019

Scientists are developing a new diagnostic tool for different types of breast cancers

Scientists are developing a new way to identify the unique chemical 'fingerprints' for different types of breast cancers.

2 Dec 2019

T Cell News and Research

Latest T Cell News and Research

Isolated components of Saussurea have positive effect on bone tissue regeneration

New human colon-on-a-chip enables in vitro study of mucus physiology

New treatment approach could improve outcomes for people with cystic fibrosis

Spinal implants could one day restore the ability to stand, walk in patients with paralysis

Multiple mechanisms at work in diabetes drug metformin

Roswell Park-led scientists identify new defense mechanism against prostate cancer

Freiburg scientists decipher basic molecular control mechanisms behind cellular identity

Researchers show how the ductal system connecting digestive organs is formed

Novel remote-controlled 'smart' platform aids in treatment of cardiovascular disease

Study finds it may be possible to treat endometriosis using an investigational cancer drug

Inhibition of a protease could improve the treatment of IBD, study shows

Streamlining Immuno-Oncological Therapeutic Antibody Discovery

Study: Calcium signaling can help address drug resistance to non-Hodgkin lymphoma

Study: TBK1 protein promotes cancer development, suppresses immune response to the disease

Study: Spleen and gut lymph nodes may serve as reservoir replication sites for HIV virus

New computational method can help predict and design allosteric functions in proteins

Discovery could offer insight into different risk of diseases in African Americans

Key component of immune response is activated by short RNAs, shows study

New findings regarding maintenance and functioning of the endosome

Scientists are developing a new diagnostic tool for different types of breast cancers

Immunology eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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