T Cell News and Research

Latest T Cell News and Research

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

1 Dec 2021

Grouping of immunological T-cell receptors may be key to identifying patients' history of infection

Grouping of pathogen-recognizing proteins on immune T cells may be key to identifying if someone has had an infection in the past, suggests a study published today in eLife.

1 Dec 2021

Northwestern researchers continue to tackle every facet of COVID-19 pandemic

As the COVID-19 pandemic nears the two-year mark, Northwestern Medicine scientists continue to tackle every facet of the disease, from investigating coronavirus vaccines' potential for providing immunity against similar coronaviruses to developing novel rapid antigen-based tests and examining disparities in COVID-19 case and mortality rates in Chicago.

30 Nov 2021

Omicron and other coronavirus variants: What you need to know

Americans, already weary of a pandemic nearly two years long, were dealt a new blow during the long Thanksgiving weekend: the announcement that a new coronavirus variant had emerged.

30 Nov 2021

Cytomegalovirus herpesvirus can accelerate the decline of the immune system, study finds

A research team at the University of Córdoba is studying the alterations that occur in the immune system's T lymphocytes with respect to age and in relation to the cytomegalovirus herpesvirus.

29 Nov 2021

Safety and immunogenicity of COVID-19 peptide vaccine

In a study published in Nature, researchers from University Hospital Tübingen have been investigating the results from a Phase I trial for a new vaccine against SARS-CoV-2 variants.

25 Nov 2021

SARS-CoV-2 reinfection and the natural immune response

Researchers review available literature on immunity and SARS-CoV-2 infection to elucidate mechanisms behind SARS-CoV-2 immunity and reinfections.

24 Nov 2021

CIRM awards $4.1 million to advance CAR T-cell therapy from the lab to clinic

On November 23, 2021, the California Institute for Regenerative Medicine (CIRM) governing board approved a $4.1 million grant to enable University of California San Diego School of Medicine researchers to advance a new chimeric antigen receptor (CAR) T-cell therapy from the laboratory into the clinic.

24 Nov 2021

An assessment of potential epitopes in SARS-CoV-2 structural proteins

Researchers utilized multiple bioinformatics resources to identify potent T- and B-cell epitopes of four SARS-CoV-2 structural proteins.

24 Nov 2021

Finding potential biomarkers to predict response to immunotherapy in nonhypermutated cancers

Scientists have discovered a potential biomarker that could more accurately identify which patients with non-hypermutated cancers will respond to specialized immunotherapy drugs called immune checkpoint inhibitors, according to findings published in Science Translational Medicine.

24 Nov 2021

GABA secreted by B-cells blunts the body's cytotoxic T-cell-based response to tumors

A group of scientists led by researchers from the RIKEN Center for Integrative Medical Sciences have discovered that B-cells, a type of immune cell, secrete the neurotransmitter GABA, and also found that the GABA secreted by the B-cells promoted the emergence of anti-inflammatory macrophages, blunting the body's cytotoxic T-cell-based response to tumors.

21 Nov 2021

Severe COVID-19 patients have significantly higher NK and T cell frequency

A new study published in the open-access journal Cells aimed to clarify the role of NK and T cell subsets in SARS-CoV-2 infection in hospitalized COVID-19 patients to unravel their potential association with disease severity.

18 Nov 2021

Short-term severe calorie restriction safe, feasible, and well tolerated by cancer patients

A diet involving short-term, severe calorie restriction was safe, feasible, and resulted in a decrease of blood glucose and growth factor concentration, reduction in peripheral blood immunosuppressive cells, and enhanced intratumor T-cell infiltration in cancer patients receiving standard-of-care therapy, according to the results of a clinical trial.

18 Nov 2021

Phantosmia, parosmia, and dysgeusia in COVID-19 patients

A team of researchers investigated qualitative aspects of olfactory and gustatory symptoms such as phantosmia, parosmia, and dysgeusia and their possible co-relation with the adaptive immune system.

17 Nov 2021

Deficient spike-specific T cell responses and inability to neutralize SARS-CoV-2 variants 12 month post-infection

Researchers conducted a comprehensive, longitudinal, long-term immune study, including functional assays to assess immune fitness against antigenically different VoC. The study is currently available on the preprint server medRxiv* while awaiting peer review.

15 Nov 2021

Researchers develop a highly efficient method to generate immune cells for cancer therapies

A Ludwig Cancer Research study has devised a highly efficient method to generate large numbers of immune cells specifically engineered to recognize neoantigens - small fragments of randomly mutated proteins that are typically unique to a patient's cancer - and destroy the tumors that express them.

15 Nov 2021

Immune response elicited by SARS-CoV-2 vaccines in infliximab and vedolizumab-treated patients with IBD

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T Cell News and Research

Latest T Cell News and Research

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

Grouping of immunological T-cell receptors may be key to identifying patients' history of infection

Northwestern researchers continue to tackle every facet of COVID-19 pandemic

Omicron and other coronavirus variants: What you need to know

Cytomegalovirus herpesvirus can accelerate the decline of the immune system, study finds

Safety and immunogenicity of COVID-19 peptide vaccine

SARS-CoV-2 reinfection and the natural immune response

CIRM awards $4.1 million to advance CAR T-cell therapy from the lab to clinic

An assessment of potential epitopes in SARS-CoV-2 structural proteins

Finding potential biomarkers to predict response to immunotherapy in nonhypermutated cancers

GABA secreted by B-cells blunts the body's cytotoxic T-cell-based response to tumors

Severe COVID-19 patients have significantly higher NK and T cell frequency

Short-term severe calorie restriction safe, feasible, and well tolerated by cancer patients

Phantosmia, parosmia, and dysgeusia in COVID-19 patients

Deficient spike-specific T cell responses and inability to neutralize SARS-CoV-2 variants 12 month post-infection

Researchers develop a highly efficient method to generate immune cells for cancer therapies

Immune response elicited by SARS-CoV-2 vaccines in infliximab and vedolizumab-treated patients with IBD

Study identifies a host factor that reflects different levels of inflammation within mild COVID-19 cases

Mycobacterium tuberculosis may induce resistance to secondary SARS-CoV-2 infection

Increased risk of breakthrough SARS-CoV-2 infection with ChAdOx1 compared to BNT162b2 vaccine

Immunology eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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