T Cell News and Research

Latest T Cell News and Research

Blocking metastasis-promoting enzyme can prevent spread of breast cancer

In a breakthrough with important implications for the future of immunotherapy for breast cancer, UC San Francisco scientists have found that blocking the activity of a single enzyme can prevent a common type of breast cancer from spreading to distant organs.

14 Nov 2019

Knocking out 'survival system' of cancer cells could improve effectiveness of melanoma treatment

The effectiveness of current treatments for melanoma, the deadliest form of skin cancer, could be improved by using approaches that wipe out the 'survival system' of cancer cells according to a study published in Nature Communications today.

14 Nov 2019

Lonza launches new basal and feed medium to optimize protein production

Lonza has further expanded its cell culture media portfolio with the addition of the eCHO Basal Medium and Feed, which has been designed to optimize protein production by delivering a consistent yield and highly viable cells while keeping lactate levels to a minimum for optimal protein integrity.

From Lonza 14 Nov 2019

Turbine secures institutional financing of €3m to expand potential of simulation-first drug discovery

Turbine, a simulation-based drug discovery company today announced the closing of an institutional financing round led by Delin Ventures.

From Turbine Simulated Cell Technologies Ltd. 14 Nov 2019

Targeting the formation of alpha-synuclein aggregates may slow Parkinson's progression

Aggregates of the protein alpha-synuclein arising in the gut may play a key role in the development of Parkinson's disease.

13 Nov 2019

Cleveland Clinic researchers identify novel target for anti-fibrotic therapies

In a new study published in Science Signaling, Cleveland Clinic researchers have identified a novel target for new therapies that may help to treat or prevent a host of fibrotic conditions, which contribute to nearly half of overall mortality in the United States.

13 Nov 2019

Machine learning algorithm predicts life expectancy in heart failure patients

When Avi Yagil, PhD, Distinguished Professor of Physics at University of California San Diego flew home from Europe in 2012, he thought he had caught a cold from his travels. When a "collection of pills" did not improve his symptoms, his wife encouraged him to see a doctor.

13 Nov 2019

Deterministic mechanoporation of cells en masse to cure cancer

What if you could cure cancer by re-engineering patients' cells to better target and destroy their own tumors? With the advent of powerful new cellular engineering technologies, this is no longer the stuff of science fiction.

13 Nov 2019

Uncovering the secret weapon of rabies viruses

In a new study published in the journal Cell Reports, scientists have discovered the exact site at which the immune system is disabled by the rabies virus, opening the way for a new and highly effective means of rabies prevention. This is a long-awaited discovery and could transform the field of rabies immunization.

13 Nov 2019

New biomarker discovered in cancer stem cells

In the world of cancer biology, not all biomarkers are created equal. These molecules that alert doctors that an abnormal process may be underway can appear as an array of aberrant proteins, such as hormones, enzymes or signaling molecules, and vary from patient to patient. Because they are a mixed bag, no one drug exists to attack them.

13 Nov 2019

Researchers find mechanism that controls the growth of B1-cells

Directly after birth, the immune system completes production of a subtype of antibody-producing immune cells, B-1, that are to last for a lifetime. No more B1-cells are formed after that point. However, these cells are self-reactive - they produce not only antibodies against foreign substances, but also against the body's own substances, and it is unclear why the immune system allows for the development of these particular cells.

13 Nov 2019

Tulane virus needs intracellular calcium to replicate

Some gastrointestinal viruses need calcium. They need calcium ions to carry out several essential aspects of viral life, such as entry into host cells, genome replication and building new viruses to invade other cells. The cells invaded by viruses also use calcium. They use it as signals to regulate many of the cells' own processes, but viruses can takeover cellular calcium signaling to satisfy their own needs.

13 Nov 2019

Clinical analysis reveals high expression of apoptosis protein in chemoresistant TNBC

78 TNBC biopsies from patients with different responses to chemotherapy were analysed for API-5 expression before any treatment.

13 Nov 2019

Researchers develop novel mathematical framework for mapping out drug interaction

Combining two or more drugs can be an effective treatment of diverse diseases, such as cancer. Yet, at the same time, the wrong drug combination can cause major side effects. Currently there is no systematic understanding of how different drugs influence each other. Thus, elucidating how two given drugs interact, and whether they have a beneficial effect, would mean a major step towards drug development to treat diseases more effectively in the future.

13 Nov 2019

Fertilization discovery reveals egg's role, potentially paves way for new contraceptive

An unexpected discovery about fertilization from the University of Virginia School of Medicine reveals new insights on how sperm and egg fuse and could have major implications for couples battling infertility – and may lead to a future male contraceptive.

13 Nov 2019

Scientists explore expansion of cytotoxic CD4 T-cells in supercentenarians

Scientists from the RIKEN Center for Integrative Medical Science (IMS) and Keio University School of Medicine in Japan have used single-cell RNA analysis to find that supercentenarians--meaning people over the age of 110--have an excess of a type of immune cell called cytotoxic CD4 T-cells.

13 Nov 2019

T Cell News and Research

Latest T Cell News and Research

Blocking metastasis-promoting enzyme can prevent spread of breast cancer

Knocking out 'survival system' of cancer cells could improve effectiveness of melanoma treatment

Lonza launches new basal and feed medium to optimize protein production

Turbine secures institutional financing of €3m to expand potential of simulation-first drug discovery

Targeting the formation of alpha-synuclein aggregates may slow Parkinson's progression

Cleveland Clinic researchers identify novel target for anti-fibrotic therapies

Machine learning algorithm predicts life expectancy in heart failure patients

Deterministic mechanoporation of cells en masse to cure cancer

Uncovering the secret weapon of rabies viruses

New biomarker discovered in cancer stem cells

Researchers find mechanism that controls the growth of B1-cells

Tulane virus needs intracellular calcium to replicate

Clinical analysis reveals high expression of apoptosis protein in chemoresistant TNBC

Researchers develop novel mathematical framework for mapping out drug interaction

Fertilization discovery reveals egg's role, potentially paves way for new contraceptive

Scientists explore expansion of cytotoxic CD4 T-cells in supercentenarians

Researchers take major step towards developing a viable vaccine for malaria

Leukemia type B cell can transform into a macrophage through epigenetic changes

Novartis announces strategy to broaden patient reach and availability of medicines in sub-Saharan Africa

Scientists move closer towards developing an effective malaria vaccine

Immunology eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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