T Cell News and Research

Latest T Cell News and Research

Study shows how high glucose damages the vascular system

Diabetes, which is marked by increased glucose levels in the body, eventually leads to certain complications, including cardiovascular disease. Now, a new study shows a cellular connection between diabetes and blood vessel narrowing that boosts one’s risk of chronic and potentially fatal health conditions, including stroke and heart disease.

22 Jul 2019

Aging nerve cells fail to take out the intracellular "trash"

Researchers at the Perelman School of Medicine at the University of Pennsylvania, have found that with age the neurons or nerve cells fail to perform an activity that they could when they were younger. The team explains that normal cells take out protein and other “trash” or “garbage” through a process of autophagy. This rids the cell of the dysfunctional proteins and aggregates of unused proteins.

22 Jul 2019

NIH researchers report largest genomic study of type 2 diabetes in sub-Saharan Africans

National Institute of Health researchers have reported the largest genomic study of type 2 diabetes in sub-Saharan Africans, with data from more than 5,000 individuals from Nigeria, Ghana and Kenya.

19 Jul 2019

Defective potassium channels linked only with headaches, not body pain

Defective potassium channels involved in pain detection can increase the chance of developing a headache and could be implicated in migraines, according to research in mice published in eNeuro.

From Society for Neuroscience 19 Jul 2019

Disruption of immune cell behavior may spur heart disease, heart failure

On an ice hockey team, the players all start off with identical uniforms, skates and a stick. But if you take one of them, add padding, a glove, and a mask; and switch the stick to one with a larger blade, then you get a goalie.

From Johns Hopkins Medicine 19 Jul 2019

Group of genes linked to longer lifespan in fruit flies discovered

Alexey Moskalev, Ph.D., Head of the Laboratory of Geroprotective and Radioprotective technologies, and co-authors from the Institute of biology of Komi Science Center of RAS, the Engelgard's Institute of molecular biology of RAS and Moscow Institute of Physics and Technology published a scientific article titled "Transcriptome Analysis of Long-lived Drosophila melanogaster E(z) Mutants Sheds Light on the Molecular Mechanisms of Longevity" in Nature Scientific Reports - the leading international multidisciplinary weekly journal.

19 Jul 2019

How genetic differences in Epstein-Barr virus strains alter the way it behaves

Researchers at the University of Sussex have identified how differences in the genetic sequence of the two main strains of the cancer-associated Epstein-Barr virus can alter the way the virus behaves when it infects white blood cells.

19 Jul 2019

Receptor in the uterus can detect sperm molecule, aids in sperm survival

Why does it take 200 million sperms to fertilize a single egg? The single sperm that reached the finished line has successfully survived multiple checkpoints within the female reproductive tract, dubbed as pre-fertilization events. Now, a new study shows that the uterus contains receptors that facilitate sperm survival.

19 Jul 2019

Study uncovers gene that hides tumor cells from immunotherapy

A team at Fred Hutchinson Cancer Research Center has identified a gene that could make immunotherapy treatments, specifically checkpoint inhibitors, work for a wider variety of cancer patients.

19 Jul 2019

Low estrogen causes muscle loss in women after menopause

Pioneering research shows the essential role played by the female hormone estrogen in preserving muscle bulk and strength in women.

19 Jul 2019

Key metabolic changes found in patients with chemotherapy-related heart toxicity

More and more patients are being treated successfully for cancer. However, some cancer treatments that are very effective for breast cancer – medications like anthracyclines and trastuzumab – can cause heart dysfunction and lead to heart failure.

19 Jul 2019

Alzheimer's gene may affect cognitive health before adulthood, study finds

The Apolipoprotein E (APOE) is a major cholesterol carrier that aids in lipid transport and injury repair in the brain. It packages cholesterol and other fats and moves them through the bloodstream. APOE polymorphic alleles are the major genetic factors for the risk of Alzheimer’s disease (AD).

19 Jul 2019

Resveratrol found in grapes could help astronauts on Mars

For the first humans on landing on Mars, a natural ingredient resveratrol could help prevent muscle atrophy due to zero gravity says a report in the Frontiers in Physiology.

18 Jul 2019

AEBP1 gene may play key role in the development and severity of liver disease

Researchers have found that a gene known as AEBP1 may play a central role in the development, severity and potential treatment of liver disease, according to a study by Temple University, the Geisinger Obesity Institute and the Translational Genomics Research Institute, an affiliate of City of Hope.

18 Jul 2019

Study reveals how aggressive prostate cancer metastasizes by evading the immune system

Researchers at The University of Texas MD Anderson Cancer Center have discovered how an aggressive form of prostate cancer called double-negative prostate cancer (DNPC) metastasizes by evading the the immune system.

18 Jul 2019

Getting rid of chronic infections by waking up sleeping bacteria

Researchers in the group of Jan Michiels (VIB-KU Leuven Center for Microbiology) identified a mechanism of how sleepy bacteria wake up.

18 Jul 2019

Research team detects novel mechanism of inheritance

Non-Mendelian, oligogenic inheritance could bean unrecognized and important element for occurrence ofhereditary retinal degenerations (HRDs, comprising retinitis pigmentosa) which are caused by ultra-rare mutations and cause progressive blindness.

18 Jul 2019

Novel insight into microRNA function can be crucial for the development of gene therapy

Scientists at the University of Eastern Finland and the University of Oxford have shown that small RNA molecules occurring naturally in cells, i.e. microRNAs, are also abundant in cell nuclei.

18 Jul 2019

Cancer stem cells elude the body's immune cells by deactivating danger detector

Acute myeloid leukemia stem cells elude the body's immune cells by deactivating a danger detector. The underlying mechanisms and the potential new therapeutic approaches that this gives rise to have been detailed in the journal Nature by researchers from the University of Basel and University Hospital Basel in collaboration with colleagues in Germany.

18 Jul 2019

Light at last: why do more women develop Alzheimer’s disease?

Alzheimer’s disease (AD) is a leading cause of dementia in many older people, but it seems to affect twice as many women as men. Scientists have long tried to find out why this is so, and why it seems to follow a fast-track course in women.

18 Jul 2019