T Cell News and Research

Latest T Cell News and Research

FDA accepted PD-L1 inhibitor durvalumab for the treatment of endometrial cancer

On June 14, 2024, the U.S. FDA approved AstraZeneca's Durvalumab (IMFINZI®) for primary advanced or recurrent endometrial cancer with mismatch repair deficiency. Endometrial cancer is the most prevalent gynecologic cancer, with an estimated 66,200 new U.S. cases in 2023.

From Sino Biological Inc. 5 Aug 2024

Active immune cells discovered in brain's cranial bone marrow fighting glioblastomas

A study uncovers the presence and activity of immune cells in glioblastoma, revealing new insights into brain tumor immunology and potential treatment avenues.

4 Aug 2024

New AI test may help bowel cancer patients avoid unnecessary chemotherapy

A new artificial intelligence (AI) test to determine the risk of bowel cancers coming back could help patients avoid chemotherapy, according to new research led by the University of Leeds.

31 Jul 2024

Neurodivergent children face higher risk of chronic disabling fatigue by 18, study finds

Neurodivergent traits in childhood double the risk of chronic disabling fatigue by age 18, with inflammation playing a significant mediating role. This highlights the importance of addressing inflammatory markers in managing the health of neurodivergent individuals.

31 Jul 2024

MD Anderson and collaborators initiate space project to explore T cell behavior in microgravity

The University of Texas MD Anderson Cancer Center and collaborators are initiating a research project that will send T cells to the International Space Station (ISS) to study the effects of prolonged microgravity on cell differentiation, activation, memory and exhaustion.

31 Jul 2024

Can diet alter your biological age?

Research shows that healthy diets lower epigenetic age while added sugar accelerates aging in midlife Black and White women.

31 Jul 2024

ACE technology enhances single-cell protein detection with advanced signal amplification

Since the 1950s, researchers have used a famous method invented by Wallace Coulter known as "flow cytometry" to characterize different types of immune cells in research studies and in blood samples from human individuals.

30 Jul 2024

Loss of Gα13 in B-cells linked to increased lymphoma risk due to dietary glutamine

Researchers find that the deletion of Gα13 in B-cells increases lymphoma risk by enhancing proliferation in gut-associated lymph nodes. Dietary glutamine significantly promotes these effects, highlighting a crucial link between diet and cancer.

29 Jul 2024

Overcoming cancer relapse with CAR-Enhancer therapy

Even as they have revolutionized the treatment of certain forms of cancer, CAR T-cell therapies have been shadowed by a significant limitation: many patients, including those whose cancer goes into full remission, eventually relapse. In a new study, Dana-Farber Cancer Institute researchers report on a technique with the potential to eliminate that problem.

29 Jul 2024

Exploring alemtuzumab in reduced-toxicity conditioning for Asian patients with inborn errors of immunity

Allogeneic hematopoietic cell transplantation (HCT) is a commonly used curative therapy for individuals with inborn errors of immunity (IEI).

28 Jul 2024

Moffitt study identifies predictive biomarkers for immunotherapy in merkel cell carcinoma

Merkel cell carcinoma is a rare but highly aggressive form of skin cancer known for its rapid growth and tendency to metastasize. Despite the promise of immune checkpoint blockade therapy, which can boost the body's immune response against cancer cells, nearly half of patients do not respond to this treatment.

26 Jul 2024

INTEGRA Biosciences and Parse Biosciences offer affordable, automated single cell RNA sequencing

INTEGRA Biosciences and Parse Biosciences have partnered to automate single cell RNA sequencing (scRNA-seq) on the ASSIST PLUS pipetting robot.

From INTEGRA Biosciences 26 Jul 2024

Study highlights infection as major post-CAR-T therapy challenge

In patients with diffuse large B-cell non-Hodgkin lymphoma (DLBCL), the two hallmark post-chimeric antigen receptor (CAR)-T therapy toxicities are extremely rare after two weeks, supporting a shorter, more flexible toxicity monitoring period, according to a study published in Blood Advances.

25 Jul 2024

Simple blood test may predict CAR-T therapy success in multiple myeloma

A simple blood test that measures the number of lymphocytes, a type of white blood cell in the body, may predict whether people who have relapsed multiple myeloma are going to respond well to CAR-T immunotherapy, according to new research from Weill Cornell Medicine, NewYork-Presbyterian, Columbia University and Icahn School of Medicine at Mount Sinai.

24 Jul 2024

Unraveling the role of TAL1 and miR-146b-5p in T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive form of leukemia that arises from the malignant transformation of T-cell progenitors.

23 Jul 2024

Researchers discover new target for treating diseases linked to T-cell leukemia virus type 1

A team of researchers from Penn State College of Medicine found a new target for treating diseases associated with human T-cell leukemia virus type 1 (HTLV-1).

22 Jul 2024

New combined cell therapy for kidney transplants can help reduce donor-specific immune response

A new combined cell therapy for kidney transplants can help to reduce the donor-specific reaction against the transplanted organ without the need for maintenance triple immunosuppression.

22 Jul 2024

Long-term immune changes persist in unvaccinated COVID-19 patients

Study reveals that unvaccinated individuals experience significant long-term changes in immune parameters up to ten months post-COVID-19 infection, with a shift towards a Th2 cytokine profile.

21 Jul 2024

CD5 knockout using CRISPR boosts CAR T cell therapy efficacy

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, according to a preclinical study from investigators at the University of Pennsylvania's Perelman School of Medicine and Abramson Cancer Center.

19 Jul 2024

Unexpected T-cell reactions to adenoviral COVID-19 vaccines discovered

Researchers from the University of Liverpool's Centre for Drug Safety Science have identified unpredicted T-cell immune responses to the adenoviral (Oxford/AstraZeneca and Janssen) COVID-19 vaccines, but not to the mRNA vaccines.

19 Jul 2024

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T Cell News and Research

Latest T Cell News and Research

FDA accepted PD-L1 inhibitor durvalumab for the treatment of endometrial cancer

Active immune cells discovered in brain's cranial bone marrow fighting glioblastomas

New AI test may help bowel cancer patients avoid unnecessary chemotherapy

Neurodivergent children face higher risk of chronic disabling fatigue by 18, study finds

MD Anderson and collaborators initiate space project to explore T cell behavior in microgravity

Can diet alter your biological age?

ACE technology enhances single-cell protein detection with advanced signal amplification

Loss of Gα13 in B-cells linked to increased lymphoma risk due to dietary glutamine

Overcoming cancer relapse with CAR-Enhancer therapy

Exploring alemtuzumab in reduced-toxicity conditioning for Asian patients with inborn errors of immunity

Moffitt study identifies predictive biomarkers for immunotherapy in merkel cell carcinoma

INTEGRA Biosciences and Parse Biosciences offer affordable, automated single cell RNA sequencing

Study highlights infection as major post-CAR-T therapy challenge

Simple blood test may predict CAR-T therapy success in multiple myeloma

Unraveling the role of TAL1 and miR-146b-5p in T-cell acute lymphoblastic leukemia

Researchers discover new target for treating diseases linked to T-cell leukemia virus type 1

New combined cell therapy for kidney transplants can help reduce donor-specific immune response

Long-term immune changes persist in unvaccinated COVID-19 patients

CD5 knockout using CRISPR boosts CAR T cell therapy efficacy

Unexpected T-cell reactions to adenoviral COVID-19 vaccines discovered

Immunology eBook

Leveraging the Radian ASAP in standard casework

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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