T Cell News and Research

Latest T Cell News and Research

Study shows CAR T-cell therapy's risk of second primary malignancies comparable to other treatments

The frequency of second primary malignancies (SPMs) arising in cancer survivors following treatment with CAR T-cell therapy was statistically comparable to the frequency of SPMs following other standard-of-care therapies, according to a systematic review and meta-analysis.

11 Sep 2024

Cancer drug offers life-changing results for severe lupus patient

The team at Charité – Universitätsmedizin Berlin is astounded by the huge improvement seen in a female patient with severe systemic lupus erythematosus (SLE) after being treated with the cancer medication teclistamab. Not long ago, the 23-year-old was wheelchair-bound due to the autoimmune disease.

6 Sep 2024

Delayed antiviral treatment still beneficial for immunocompromised COVID-19 patients

Starting antiviral treatment as late as 14 days after infection with SARS-CoV-2 may still be beneficial in hosts with compromised immune systems, who are at greatest risk of developing severe COVID-19, according to researchers in the Center for Translational Antiviral Research at Georgia State University's Institute for Biomedical Sciences.

3 Sep 2024

Intranasal vaccine shows broad SARS-CoV-2 variant protection

Study demonstrates that a single-dose intranasal live-attenuated vaccine, CDO-7N-1, provides broad protection against SARS-CoV-2 and its variants by inducing potent immune responses, including neutralizing antibodies and T-cell activity, in animal models.

1 Sep 2024

Octavalent intranasal flu vaccine proves effective in neutralizing both existing and emerging strains

A new octavalent intranasal vaccine shows promising results in providing broad immunity against both seasonal and pre-pandemic influenza strains by eliciting strong mucosal and systemic immune responses in ferrets.

25 Aug 2024

New project aims to study the combination of two therapies for pediatric brain cancer

Natasha Sheybani, assistant professor of biomedical engineering at the University of Virginia School of Engineering, will collaborate with researchers at Children's National Hospital to study the combination of two therapies for pediatric brain cancer.

19 Aug 2024

Study reveals a paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia

Researchers at Children's Hospital of Philadelphia (CHOP), St. Jude Children's Research Hospital (St. Jude) and the Children's Oncology Group (COG) today announced a significant paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia (T-ALL), an aggressive and high-risk form of cancer, to one frequently driven by genetic changes in non-coding portions of our DNA.

14 Aug 2024

New trial explores BAFF CAR T-cell therapy for relapsed myeloma

University Hospitals (UH) Seidman Cancer Center hematologist-oncologist Leland Metheny, MD, is leading the trial.

14 Aug 2024

Exploring the distinct characteristics of Nodular Lymphocyte Predominant Hodgkin Lymphoma

This review offers an in-depth exploration of Nodular Lymphocyte Predominant Hodgkin Lymphoma (NLPHL), highlighting its distinct characteristics across various domains such as epidemiology, clinical presentation, histopathology, immunophenotype, genetic findings, and challenges in differential diagnosis.

13 Aug 2024

EZH2's role in cancer progression and therapy explored

Enhancer of zeste homolog 2 (EZH2) is a catalytic subunit of the Polycomb-repressive complex 2 (PRC2), which plays a crucial role in transcriptional repression through the methylation of histone H3 on lysine 27 (H3K27me3).

9 Aug 2024

Study links renalase-1 and T-cell receptor interaction to increased melanoma survival

A new research paper was published in Oncotarget's Volume 15 on August 5, 2024, entitled, "Chemical complementarity of tumor resident, T-cell receptor CDR3s and renalase-1 correlates with increased melanoma survival."

8 Aug 2024

Individualized neoantigen cancer therapy demonstrates safety and efficacy in early trials

For decades, researchers have worked to develop therapies that can prime the immune system to recognize and attack proteins on the surface of tumor cells.

8 Aug 2024

Research reveals autoimmune mechanism behind multisystem inflammatory syndrome in children

Study reveals a mechanism behind multisystem inflammatory syndrome in children (MIS-C).

7 Aug 2024

The real cost of processed foods: How Western diets are harming global health

A recent study in Nature Medicine reviews the adverse effects of Western diets on human health, highlighting increased risks of chronic diseases and gut dysbiosis. Researchers call for global awareness and promotion of healthier dietary patterns.

6 Aug 2024

Enhanced CAR T-cell homing boosts treatment efficacy for osteosarcoma

Chimeric antigen receptor (CAR) T–cell immunotherapy re-engineers a patient's immune cells to target cancer cells.

5 Aug 2024

FDA accepted PD-L1 inhibitor durvalumab for the treatment of endometrial cancer

On June 14, 2024, the U.S. FDA approved AstraZeneca's Durvalumab (IMFINZI®) for primary advanced or recurrent endometrial cancer with mismatch repair deficiency. Endometrial cancer is the most prevalent gynecologic cancer, with an estimated 66,200 new U.S. cases in 2023.

From Sino Biological Inc. 5 Aug 2024

Active immune cells discovered in brain's cranial bone marrow fighting glioblastomas

A study uncovers the presence and activity of immune cells in glioblastoma, revealing new insights into brain tumor immunology and potential treatment avenues.

4 Aug 2024

New AI test may help bowel cancer patients avoid unnecessary chemotherapy

A new artificial intelligence (AI) test to determine the risk of bowel cancers coming back could help patients avoid chemotherapy, according to new research led by the University of Leeds.

31 Jul 2024

Neurodivergent children face higher risk of chronic disabling fatigue by 18, study finds

Neurodivergent traits in childhood double the risk of chronic disabling fatigue by age 18, with inflammation playing a significant mediating role. This highlights the importance of addressing inflammatory markers in managing the health of neurodivergent individuals.

31 Jul 2024

MD Anderson and collaborators initiate space project to explore T cell behavior in microgravity

The University of Texas MD Anderson Cancer Center and collaborators are initiating a research project that will send T cells to the International Space Station (ISS) to study the effects of prolonged microgravity on cell differentiation, activation, memory and exhaustion.

31 Jul 2024

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T Cell News and Research

Latest T Cell News and Research

Study shows CAR T-cell therapy's risk of second primary malignancies comparable to other treatments

Cancer drug offers life-changing results for severe lupus patient

Delayed antiviral treatment still beneficial for immunocompromised COVID-19 patients

Intranasal vaccine shows broad SARS-CoV-2 variant protection

Octavalent intranasal flu vaccine proves effective in neutralizing both existing and emerging strains

New project aims to study the combination of two therapies for pediatric brain cancer

Study reveals a paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia

New trial explores BAFF CAR T-cell therapy for relapsed myeloma

Exploring the distinct characteristics of Nodular Lymphocyte Predominant Hodgkin Lymphoma

EZH2's role in cancer progression and therapy explored

Study links renalase-1 and T-cell receptor interaction to increased melanoma survival

Individualized neoantigen cancer therapy demonstrates safety and efficacy in early trials

Research reveals autoimmune mechanism behind multisystem inflammatory syndrome in children

The real cost of processed foods: How Western diets are harming global health

Enhanced CAR T-cell homing boosts treatment efficacy for osteosarcoma

FDA accepted PD-L1 inhibitor durvalumab for the treatment of endometrial cancer

Active immune cells discovered in brain's cranial bone marrow fighting glioblastomas

New AI test may help bowel cancer patients avoid unnecessary chemotherapy

Neurodivergent children face higher risk of chronic disabling fatigue by 18, study finds

MD Anderson and collaborators initiate space project to explore T cell behavior in microgravity

Immunology eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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