T Cell News and Research

Latest T Cell News and Research

Feast and famine diet may restore insulin production in diabetes

A landmark study conducted by the University of Southern California and published this week in the journal Cell provides hope for restoring insulin production in patients with diabetes. The study showed that when food is restored to mice on a very low calorie diet that mimics fasting, new insulin-producing cells develop.

24 Feb 2017

Discovery of dual role played by PGK1 enzyme may indicate new therapeutic target for brain cancer

Discovery of a dual role played by the enzyme phosphoglycerate kinase 1 (PGK1) may indicate a new therapeutic target for glioblastoma, an often fatal form of brain cancer, according to researchers at The University of Texas MD Anderson Cancer Center.

24 Feb 2017

Decoding the Exposome Through Breath Biomarkers

The human exposome is probably best defined as “everything that is not the genome.” This is a bit tongue in cheek, but basically, the exposome is comprised of all of the chemicals in your body from the environment, food, consumer products, their metabolites, the endogenous “housekeeping” chemicals, the cellular wastes from energy production, as well as all of the messenger compounds and life supporting chemicals.

From Pittcon 24 Feb 2017

Study shows how old blood stem cells can be rejuvenated

When we are young, our blood stem cells produce an even and well-balanced number of red and white blood cells according to need. As we age, however, the capacity of the blood stem cells to produce the number of blood cells we need declines.

24 Feb 2017

Initial diagnosis of acute kidney injury may be inaccurate for many patients, study suggests

Researchers from Columbia University Medical Center have found that, for many patients, an initial diagnosis of "acute kidney injury" may have been inaccurate.

24 Feb 2017

New research offers insights into how differences arise in common illnesses

As much as we try to avoid it, we are constantly sharing germs with those around us. But even when two people have the same infection, the resulting illnesses can be dramatically different--mild for one person, severe or even life-threatening for the other.

24 Feb 2017

NR could potentially prevent chemotherapy-induced peripheral neuropathy in cancer patients

A new study in rats suggests that nicotinamide riboside (NR), a form of vitamin B3, may be useful for treating or preventing nerve pain (neuropathy) caused by chemotherapy drugs.

24 Feb 2017

Researchers develop new assay for measuring underlying autoimmunity in rheumatoid arthritis patients

Current treatments for rheumatoid arthritis relieve the inflammation that leads to joint destruction, but the immunologic defect that triggers the inflammation persists to cause relapses, according to research conducted at NYU Langone Medical Center and the University of Pittsburgh.

24 Feb 2017

Researchers reveal biological pathways involved in diabetic kidney disease

Diabetes is a leading cause of kidney disease, a serious, often fatal complication that is difficult to diagnose in early, potentially treatable stages.

24 Feb 2017

Study uncovers how effects of HSP90 protein can alter course of genetic diseases

Proteins do most of the work inside the human body, supporting the structure, function, regulation, and repair of organs, tissues and cells.

24 Feb 2017

BUSM researchers uncover unique patterns of protein synthesis linked to increased longevity

Aging is a complex process that involves multiple metabolic and regulatory pathways. Previous studies have identified hundreds of genes whose deletion can significantly increase lifespan in model organisms. Yet, how these different aging genes and pathways are interconnected remains poorly understood.

23 Feb 2017

NSAIDs could potentially be repurposed as life-saving treatment for sepsis, research suggests

A potentially life-saving treatment for sepsis has been under our noses for decades in the non-steroidal anti-inflammatory drugs most people have in their medicine cabinets, a new University of Colorado Boulder study suggests.

23 Feb 2017

Researchers develop new tool that quickly reveals metabolic fluxes in cells

If we were to take photographs at the underground stations in Barcelona, we would see the number of people waiting, find out what time the rush hour takes place and deduce why some stations are busier than others.

23 Feb 2017

Lack of methyl groups in gene body may lead to emergence of cancer

Every cell in our body contains the complete DNA library. So-called methyl groups regulate that in body tissues only the genetic information is expressed that is indeed needed in this tissue.

23 Feb 2017

New compounds with potent anticancer activity could lessen side effects of oncological treatments

The Universitat Jaume I, the Spanish Centre for Advanced Scientific Research and the University of Pavia have patented new compounds with potent anticancer activity in breast and colon tumour cell lines that have low toxicity in healthy cells, which can dramatically decrease side effects during chemotherapy treatment.

23 Feb 2017

Researchers find new evidence to support structure-based classification system for viruses

Professor Robert Sinclair at the Okinawa Institute of Science and Technology Graduate University and Professor Dennis Bamford and Dr. Janne Ravantti from the University of Helsinki have found new evidence to support a classification system for viruses based on viral structure.

23 Feb 2017

Mayo Clinic study finds link between biology of aging and idiopathic pulmonary fibrosis

A Mayo Clinic study has shown evidence linking the biology of aging with idiopathic pulmonary fibrosis, a disease that impairs lung function and causes shortness of breath, fatigue, declining quality of life, and, ultimately, death.

23 Feb 2017

Study identifies new role of cholesterol in regulating brain proteins

A study led by researchers at the Hospital del Mar Medical Research Institute and the Institute of Medical Physics and Biophysics at the Faculty of Medicine in Charité Hospital, Berlin, published in the journal Nature Communications, demonstrates that the cholesterol present in cell membranes can interfere with the function of an important brain membrane protein, through a previously unknown mode of interaction.

23 Feb 2017

Scientists propose potential new treatment for Gaucher disease

Scientists propose in Nature blocking a molecule that drives inflammation and organ damage in Gaucher and maybe other lysosomal storage diseases as a possible treatment with fewer risks and lower costs than current therapies.

23 Feb 2017

MSK researchers harness power of CRISPR/Cas9 to create more-potent CAR T cells

Researchers from Memorial Sloan Kettering Cancer Center have harnessed the power of CRISPR/Cas9 to create more-potent chimeric antigen receptor (CAR) T cells that enhance tumor rejection in mice.

23 Feb 2017

T Cell News and Research

Latest T Cell News and Research

Feast and famine diet may restore insulin production in diabetes

Discovery of dual role played by PGK1 enzyme may indicate new therapeutic target for brain cancer

Decoding the Exposome Through Breath Biomarkers

Study shows how old blood stem cells can be rejuvenated

Initial diagnosis of acute kidney injury may be inaccurate for many patients, study suggests

New research offers insights into how differences arise in common illnesses

NR could potentially prevent chemotherapy-induced peripheral neuropathy in cancer patients

Researchers develop new assay for measuring underlying autoimmunity in rheumatoid arthritis patients

Researchers reveal biological pathways involved in diabetic kidney disease

Study uncovers how effects of HSP90 protein can alter course of genetic diseases

BUSM researchers uncover unique patterns of protein synthesis linked to increased longevity

NSAIDs could potentially be repurposed as life-saving treatment for sepsis, research suggests

Researchers develop new tool that quickly reveals metabolic fluxes in cells

Lack of methyl groups in gene body may lead to emergence of cancer

New compounds with potent anticancer activity could lessen side effects of oncological treatments

Researchers find new evidence to support structure-based classification system for viruses

Mayo Clinic study finds link between biology of aging and idiopathic pulmonary fibrosis

Study identifies new role of cholesterol in regulating brain proteins

Scientists propose potential new treatment for Gaucher disease

MSK researchers harness power of CRISPR/Cas9 to create more-potent CAR T cells

Immunology eBook

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

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