Toxicology News and Research

Latest Toxicology News and Research

$3.2M grant to explore how chemicals affect human health

Most people would agree that arsenic, lead, mercury, benzene and carbon monoxide pose dangers to humans. Not many, though, realize that the average person is exposed to about 10,000 different chemicals per day.

12 Aug 2009

Metabolon awarded patent for metabolomics software

Metabolon, Inc. has announced that it has been awarded a patent for its metabolomics software, Ion Tracker™, which provides a mechanism for creating new chemical library entries.

11 Aug 2009

French DEET research has little relevance and is irresponsible

“Reports of a French study to examine the effects of DEET on the nervous system of insects has little relevance for the widely-used repellent ingredient’s effects on humans, according to independent scientific experts, including those at the U.S. National Pesticide Information Center,” said Susan Little, director of the DEET Education Program, Washington, D.C.

10 Aug 2009

Innexus Biotechnology announces business development initiative on lead preclinical candidate

InNexus Biotechnology Inc. announced today that the Company will embark on a business development initiative for DXL625™ (CD20), the Company’s lead preclinical candidate for the prospective treatment of Non-Hodgkin’s Lymphoma and/or Chronic Lymphocytic Leukemia.

6 Aug 2009

SAGE to publish Veterinary Pathology

SAGE is pleased to announce that it will begin publishing Veterinary Pathology, a key international journal of natural and experimental disease, beginning in 2010.

6 Aug 2009

Smoking marijuana has toxic effects on cells

In a finding that challenges the increasingly popular belief that smoking marijuana is less harmful to health than smoking tobacco, researchers in Canada are reporting that smoking marijuana, like smoking tobacco, has toxic effects on cells.

6 Aug 2009

Accidental childhood poisonings mostly due to medicines

More than two-thirds of all emergency department visits for childhood poisoning involve prescription and over-the-counter medications, more than twice the rate of poisonings from consumer products, reports a new study from the Centers for Disease Control and Prevention (CDC).

4 Aug 2009

MSU receives $1.5 million grant to help educate more Hispanics in neurosciences

A $1.5 million federal grant will help Michigan State University increase the number of Hispanic doctoral students trained in the neurosciences.

3 Aug 2009

Maternal exposure to nanoparticles related to neurological dysfunction in the mouse

Maternal exposure to nanoparticles of titanium dioxide (TiO2) affects the expression of genes related to the central nervous system in developing mice. Researchers writing in BioMed Central's open access journal Particle and Fibre Toxicology found that mice whose mothers were injected with the nanoparticles while pregnant showed alteration in gene expression related to neurological dysfunction.

28 Jul 2009

Scientists investigate health benefits of molecule associated with male sexual arousal

Medical scientists at the University of Leicester are investigating how signalling molecules known to control blood pressure and penile erection act to regulate brain function and which have potential for treatments of migraine, chronic pain, epilepsy and Alzheimer's disease.

24 Jun 2009

Antisense Therapeutics trial of ATL1101 in prostate cancer shows promise

Antisense Therapeutics Ltd. (ASX: ANP) has reported further positive results from its collaborative preclinical research studies on the therapeutic potential of ATL1101 in prostate cancer. In experimental models, ATL1101 treatment significantly enhanced the tumor-suppressive effect of the cancer drug Paclitaxel. Paclitaxel is one of a class of drugs known as taxanes.

18 Jun 2009

Improved toxicology test method

Researchers at Oregon State University recently completed the largest animal study ever done in the field of toxicology, and the findings challenge some basic concepts about how to determine what level of a cancer-causing compound can be considered safe.

18 Jun 2009

Cannabis smoke damages DNA – cancer risks

A new study published by University of Leicester researchers has found "convincing evidence" that cannabis smoke damages DNA in ways that could potentially increase the risk of cancer development in humans.

16 Jun 2009

Research finds Tamiflu and Relenza relatively safe for use in pregnancy

With the H1N1 flu outbreak now elevated to pandemic level, a new article in CMAJ (Canadian Medical Association Journal) reports that oseltamivir (Tamiflu) and zanamivir (Relenza) are relatively safe drugs for use in pregnant and breast-feeding women.

15 Jun 2009

Research links intestinal inflammation with systemic chromosome damage

UCLA scientists have linked for the first time intestinal inflammation with systemic chromosome damage in mice, a finding that may lead to the early identification and treatment of human inflammatory disorders, some of which increase risk for several types of cancer.

1 Jun 2009

Countries unite to reduce animal use in product toxicity testing worldwide

Representatives from four international agencies, including the director of the U.S. National Toxicology Program (NTP), today signed a memorandum of cooperation that could reduce the number of animals required for consumer product safety testing worldwide.

27 Apr 2009

Vaccine for Enterotoxigenic E. coli developed

A Michigan State University researcher has developed a working vaccine for a strain of E. coli that kills 2 million to 3 million children each year in the developing world.

14 Apr 2009

Therapeutic effect of imatinib improved with addition of chloroquine

The therapeutic effects of the blockbuster leukemia drug imatinib may be enhanced when given along with a drug that inhibits a cell process called autophagy, researchers from the Kimmel Cancer Center at Jefferson reported in the Journal of Clinical Investigation.

13 Apr 2009

Researchers show how PCBs may alter in utero, neonatal brain development

In three new studies - including one appearing online in the Public Library of Science - Biology (PLoS - Biology) - UC Davis researchers provide compelling evidence of how low levels of polychlorinated biphenyls (PCBs) alter the way brain cells develop.

13 Apr 2009

FDA provides positive review of InNexus Biotechnology development plan for lead preclinical candidate

InNexus Biotechnology Inc. has announced the United States Food & Drug Administration (FDA) has completed its comprehensive review of the development plans for InNexus' lead preclinical candidate, DXL625 (CD20) for the prospective treatment of Non-Hodgkin's Lymphoma (NHL) and/or Chronic Lymphocytic Leukemia (CLL).

2 Apr 2009