Toxicology News and Research

Latest Toxicology News and Research

FDA provides positive review of InNexus Biotechnology development plan for lead preclinical candidate

InNexus Biotechnology Inc. has announced the United States Food & Drug Administration (FDA) has completed its comprehensive review of the development plans for InNexus' lead preclinical candidate, DXL625 (CD20) for the prospective treatment of Non-Hodgkin's Lymphoma (NHL) and/or Chronic Lymphocytic Leukemia (CLL).

2 Apr 2009

World's first nanofluidic device with complex 3-D surfaces

Researchers at the Commerce Department's National Institute of Standards and Technology (NIST) and Cornell University have capitalized on a process for manufacturing integrated circuits at the nanometer (billionth of a meter) level and used it to develop a method for engineering the first-ever nanoscale fluidic (nanofluidic) device with complex three-dimensional surfaces.

1 Apr 2009

Link between sleeping medicine use and driving impairment

A new study from the Norwegian Institute of Public Health shows a positive link between the amount of the hypnotic (sleeping medicine) zopiclone in the blood and the chance of being assessed as impaired in a clinical examination.

29 Mar 2009

Clotrimazole drug used to treat skin conditions is a marine pollutant

Clotrimazole is a common ingredient in over-the-counter skin creams. Recent results from the University of Gothenburg, Sweden, now show that it is associated with major environmental risks. "The pharmaceuticals and chemicals in everyday use form a mixture in the ocean that has a direct impact on the growth and reproduction of organisms", says scientist Tobias Porsbring.

24 Mar 2009

Discovery of gene that plays key role in process of converting dietary carbohydrates to fat

In a new study, they disabled this gene in mice, which consequently had lower levels of body fat than their normal counterparts, despite being fed the equivalent of an 'all-you-can-eat' pasta buffet.

20 Mar 2009

Fetal alcohol syndrome testing expands

Improved technology, partnerships and collaboration across two provinces have allowed Queen's University scientists to dramatically expand the use of eye-movement tests that help identify and assess children with Fetal Alcohol Spectrum Disorder (FASD).

20 Mar 2009

Alba Therapeutics announces next clinical trial of lead compound, Larazotide Acetate

Alba Therapeutics Corporation announced today it will initiate further clinical studies for patients diagnosed with celiac disease with their lead compound, larazotide acetate.

17 Mar 2009

Simple interventions help prevent adverse cardiovascular effects caused by pollution

Diesel exhaust causes arteries to lose their flexibility. Researchers writing in BioMed Central's open access journal Particle and Fibre Toxicology found that exposure to engine pollution resulted in arterial stiffness in a group of healthy volunteers.

15 Mar 2009

Phylonix granted broad U.S. patent for assessing cardiac functions in Zebrafish

Phylonix Pharmaceuticals announced, at the Society of Toxicology Annual Meeting in Baltimore, that the U.S. Patent and Trademark Office has issued the company a broad patent for assessing the toxicity of pharmaceutical test agents on cardiovascular functions in zebrafish.

15 Mar 2009

Azaya Therapeutics selected for Nanotechnology Characterization Lab by National Cancer Institute

Azaya Therapeutics, Inc. has announced that it has been selected by the National Cancer Institute (NCI) for a research collaboration to study Azaya's lead cancer therapy, ATI - 1123.

10 Mar 2009

FDA provides positive review of InNexus' lead preclinical drug candidate

3 Mar 2009

Link between, bacteria, cancer explored with funding from American Cancer Society

The role of bacteria in the development of colorectal cancer is coming under scrutiny at the University of Rochester Medical Center, thanks to an $840,000 research award from the American Cancer Society.

3 Mar 2009

Updated formula measures kidney function more accurately

Measuring kidney function in children can be expensive, time-consuming for clinicians, and tedious for children, who may be exposed to radioactivity and subjected to a large number of blood draws.

24 Feb 2009

New understanding of health implications of nanoparticles

The smallest nano-sized silica particles used in biomedicine and engineering likely won't cause unexpected biological responses due to their size, according to work presented today.

16 Feb 2009

Medicines sold in Sweden cause serious environmental harm in India

Many of the substances in our most common medicines are manufactured in India and China.

8 Feb 2009

Shift workers' body clocks studied to prevent certain cancers

Does shift work predispose you to cancer by altering the body's response to hormones?

2 Feb 2009

Recent reports regarding mercury and high fructose

ChemRisk, a leading scientific consulting firm, was asked by the Corn Refiners Association (CRA) to examine the recent publication by Institute for Agriculture and Trade Policy (IATP), "Not So Sweet: Missing Mercury and High Fructose Corn Syrup," and the Environmental Health journal publication "Mercury from chlor-alkali plants: measured concentrations in food product sugar," by Dufault et al, 2009, and to offer our comments and analysis.

2 Feb 2009