Toxicology News and Research

Latest Toxicology News and Research

Study finds increasing incidence of hospitalizations for prescription opioid poisonings in children and teens

The overall incidence of hospitalizations for prescription opioid poisonings in children and adolescents has more than doubled from 1997 to 2012, with increasing incidence of poisonings attributed to suicide or self-inflicted injury and accidental intent, according to a new study published online by JAMA Pediatrics.

1 Nov 2016

Nano-biointeraction and nanopathology

Nanoparticles enter the organism in a number of ways. In most cases through inhalation and ingestion. When inhaled, the majority of them are expelled with the next breath. When ingested, most of them are gotten rid of through feces.

31 Oct 2016

IU scientists find evidence for link between prostate cancer and Ewing's sarcoma

Medical researchers at Indiana University Bloomington have found evidence for a link between prostate cancer, which affects millions of men age 50 and older, and Ewing's sarcoma, a rare form of cancer that affects children and young adults.

25 Oct 2016

New study raises serious safety concerns in clinical use of caspase inhibitors for liver injury

Many acute and chronic liver diseases, including alcoholic hepatitis, result from apoptotic (programmed) cell death mediated by the enzyme caspase.

20 Oct 2016

Exposure to e-cigarette vapour induces negligible or no oxidative damage to lung epithelial cells

E-cigarette vapour is much less harmful to lung cells than cigarette smoke. Lab tests show that, unlike tobacco smoke, which causes oxidative stress and cell death, e-cigarette vapour does not. Oxidative stress and cell death are driving factors in the development of many smoking-related diseases such as COPD and lung cancer.

5 Oct 2016

Prescription sleep aids may stimulate suicidal thoughts or actions

Prescription sleep aids appear to carry a rare risk of suicide, most typically when they cause the unexpected response of stimulating rather than quietening patients, researchers say.

4 Oct 2016

Blocking production of key receptor may reduce effects of cigarette smoke toxicity, study finds

A Duke University-led study shows how exposure to the particulate matter from cigarette smoke may affect early development in zebrafish embryos and increases the risk of neurological disorders and physical deformities.

4 Oct 2016

Scientists develop new method to produce embryos from non-egg cells

Scientists have shown for the first time that embryos can be made from non-egg cells, a discovery that challenges two centuries of received wisdom.

3 Oct 2016

Researchers suggest need for human studies to examine effects of cannabinoid use during pregnancy

In this new era of legalized marijuana, far too little research has been conducted on the effect of cannabis on the development of human embryos, say researchers at Georgetown University Medical Center who scoured medical literature on the topic and found what they say is worrisome animal research.

30 Sep 2016

OECD publishes novel knowledge management tools for advancing non-animal testing methods

The Organisation for Economic Co-operation and Development has recently published the first five adverse outcome pathways (AOP), three of which have been developed by the European Commission's science and knowledge service, the Joint Research Centre.

30 Sep 2016

DHA intake can prevent known trigger of lupus, study finds

A team of Michigan State University researchers has found that consuming an omega-3 fatty acid called DHA, or docosahexaenoic acid, can stop a known trigger of lupus and potentially other autoimmune disorders.

30 Sep 2016

Researchers develop new analytical capabilities to identify chemical forms of mercury in human hair

Mercury is a potent neurotoxin present in our daily lives and our body can accumulate it over the years. Food consumption, such as fish and rice, is the most common source of mercury exposure.

23 Sep 2016

Study data does not support benefits of testosterone supplementation in men with ‘low T’

The prescription of testosterone supplementation for cardiovascular health, sexual function, physical function, mood, or cognitive function in men with "low T" is not supported by clinical trials data, conclude researchers who describe a review of more than 200 clinical trials published Sept. 21 in PLOS One.

22 Sep 2016

Texas A&M research shows nicotine could help protect the aging brain

Everyone knows that tobacco products are bad for your health, and even the new e-cigarettes may have harmful toxins.

21 Sep 2016

UofL investigators to explore liver disease in comprehensive fashion

Liver diseases are clinically important health problems and are generally underappreciated. The University of Louisville has brought together a critical mass of investigators to study liver diseases in a comprehensive fashion.

14 Sep 2016

New study raises safety concerns on clinical use of caspase inhibitors for liver diseases

Many acute and chronic liver diseases, including alcoholic hepatitis, result from apoptotic (programmed) cell death mediated by the enzyme caspase. Caspase inhibitors have therapeutic potential to treat and prevent apoptosis-mediated liver injury, and some are currently in clinical trials.

9 Sep 2016

NCATS scientists identify promising compounds effective in inhibiting Zika virus replication

Researchers at the National Center for Advancing Translational Sciences recently identified compounds that potentially can be used to inhibit Zika virus replication and reduce its ability to kill brain cells.

29 Aug 2016

Study finds link between childhood manganese exposure and attentional dysfunction in rodent model

Researchers using a rodent model of childhood manganese exposure have found that too much manganese early in development causes lasting attention deficits and other impairments.

23 Aug 2016

UCLA study suggests lower BPS doses damage woman's egg cells

Bisphenol S, a chemical used to manufacture polycarbonate water bottles and many other products such as epoxy glues and cash receipts, is an increasingly common replacement for bisphenol A, the of which was discontinued because of concerns about its harmful effects on the reproductive system.

10 Aug 2016

Reproductive age-related changes in ovarian environment may contribute to infertility

Women's decreased ability to produce healthy eggs as they become older may be due to excessive scarring and inflammation in their ovaries, reports a new Northwestern Medicine study in mice.

8 Aug 2016

Toxicology News and Research

Latest Toxicology News and Research

Study finds increasing incidence of hospitalizations for prescription opioid poisonings in children and teens

Nano-biointeraction and nanopathology

IU scientists find evidence for link between prostate cancer and Ewing's sarcoma

New study raises serious safety concerns in clinical use of caspase inhibitors for liver injury

Exposure to e-cigarette vapour induces negligible or no oxidative damage to lung epithelial cells

Prescription sleep aids may stimulate suicidal thoughts or actions

Blocking production of key receptor may reduce effects of cigarette smoke toxicity, study finds

Scientists develop new method to produce embryos from non-egg cells

Researchers suggest need for human studies to examine effects of cannabinoid use during pregnancy

OECD publishes novel knowledge management tools for advancing non-animal testing methods

DHA intake can prevent known trigger of lupus, study finds

Researchers develop new analytical capabilities to identify chemical forms of mercury in human hair

Study data does not support benefits of testosterone supplementation in men with ‘low T’

Texas A&M research shows nicotine could help protect the aging brain

UofL investigators to explore liver disease in comprehensive fashion

New study raises safety concerns on clinical use of caspase inhibitors for liver diseases

NCATS scientists identify promising compounds effective in inhibiting Zika virus replication

Study finds link between childhood manganese exposure and attentional dysfunction in rodent model

UCLA study suggests lower BPS doses damage woman's egg cells

Reproductive age-related changes in ovarian environment may contribute to infertility

Forensics and toxicology - Industry Focus eBook eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Toxicology News and Research

Latest Toxicology News and Research

Forensics and toxicology - Industry Focus eBook eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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