Toxicology News and Research

Latest Toxicology News and Research

Kentucky researcher awarded NCI grant to study potential link between obesity and breast cancer

The National Cancer Institute recently awarded a $750,000 grant to University of Kentucky researcher Fredrick Onono to study the potential link between obesity and breast cancer.

14 Aug 2015

Embryonic stem cells may help researchers to study physiological effects of environmental pollutants on human health

A recent study published in the Journal of Environmental Sciences shows that embryonic stem cells could serve as a model to evaluate the physiological effects of environmental pollutants efficiently and cost-effectively.

11 Aug 2015

Roche establishes strategic alliance with Diagnostic Laboratory Services

Roche announced today the establishment of a strategic alliance with Diagnostic Laboratory Services of Aiea, Hawaii, that designates the company as a Roche Molecular Center of Excellence (MCOE) for the next five years.

From Roche Sequencing and Life Science 10 Aug 2015

15th Annual Geriatric Health Care Symposium now open for registration

Registration is now open for the 15th Annual Geriatric Health Care Symposium, "Maximizing Independence for Optimal Aging," presented by the University of Louisville Institute for Sustainable Health & Optimal Aging.

3 Aug 2015

Novel 3D human skin tissue model could help detect presence of known skin sensitizers in medical device extracts

New research shows that exposing a 3D human skin tissue model to extracts of medical device materials can detect the presence of sensitizers known to cause an allergic response on contact in some individuals. Conventional skin sensitization testing of medical devices relies on animal testing, whereas human skin models could replace animal methods, according to an article in the new journal Applied In Vitro Toxicology, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

30 Jul 2015

RGS2 protein plays significant role in healthy egg-sperm union in mice

Researchers at the National Institutes of Health have discovered a protein that plays a vital role in healthy egg-sperm union in mice. The protein RGS2 can delay an egg's development into an embryo in order to allow time for sperm to arrive and merge with the egg in a healthy fertilization process. The embryo cannot survive without the male chromosomes.

28 Jul 2015

Innovative approach to treating AAT deficiency

Researchers have demonstrated the feasibility of delivering an RNA that encodes for the protein alpha-1-antitrypsin (AAT)--which is missing or nonfunctional in the genetic disorder AAT deficiency--into cells in the laboratory, enabling the cells to produce highly functional AAT.

28 Jul 2015

Researchers decode molecular mechanism of fish toxin that has potential to treat cancer

Pathogenic bacteria develop killer machines that work very specifically and highly efficiently. Scientists from the University of Freiburg have solved the molecular mechanism of a fish toxin that could be used in the future as a medication to treat cancer. The scientists have now published their research in the journal Nature Communications.

25 Jul 2015

Dartmouth researchers perform first total syntheses of compounds involved in rapid cell death in leukemia

Dartmouth researchers and their colleagues have carried out the first total syntheses of certain compounds involved in excessive cell death in leukemia.

22 Jul 2015

Sulfur dioxide air pollutant can cause adverse effects in asthmatics

Emissions of the air pollutant sulfur dioxide have been dramatically decreased during the past 30 years but for some people even a little inhaled sulfur dioxide may still be too much.

17 Jul 2015

Novogen's Anisina granted FDA Orphan Drug Designation for neuroblastoma

US-Australian drug discovery company, Novogen Limited, today announced that it has received notification from the U.S. Food and Drug Administration that its chemotherapy candidate drug, Anisina, has been granted Orphan Drug Designation for neuroblastoma.

16 Jul 2015

$Hospitalization rates higher among people who live near hydraulic fracturing wells$

Hospitalization rates higher among people who live near hydraulic fracturing wells

Hospitalizations for heart conditions, neurological illness, and other conditions were higher among people who live near unconventional gas and oil drilling (hydraulic fracturing), according to new research from the University of Pennsylvania and Columbia University published this week in PLOS ONE.

16 Jul 2015

Novel gene therapy control system regulates expression of therapeutic transgenes

Korean researchers have described a novel control system to regulate the expression of a therapeutic transgene by targeting the passenger strand of a microRNA (miR-122) linked to the transgene.

14 Jul 2015

Study shows that Anisina has potential to improve effectiveness of chemotherapy in children with cancer

US-Australian drug discovery company, Novogen Limited, today announced details of an in vivo proof of concept study that demonstrates their lead anti-tropomyosin drug candidate, Anisina, has the potential to improve the effectiveness of chemotherapy in children and reduce life-long side-effects.

14 Jul 2015

Elsevier, NCI implement two-way linking between research articles on ScienceDirect and datasets in caNanoLab

Elsevier, a world-leading provider of scientific, technical and medical information products and services, and the US National Cancer Institute, a world-leading institute for cancer research, today announced that they have implemented two-way linking between research articles on ScienceDirect and datasets stored in NCI's cancer Nanotechnology Laboratory (caNanoLab) data portal.

9 Jul 2015

UC Davis scientists identify significant driver of neuropathic pain

Scientists at the University of California, Davis, have identified a key mechanism in neuropathic pain. The discovery could eventually benefit millions of patients with chronic pain from trauma, diabetes, shingles, multiple sclerosis or other conditions that cause nerve damage.

8 Jul 2015

Discovery could pave way to new treatments for malaria

Scientists have discovered new ways in which the malaria parasite survives in the blood stream of its victims, a discovery that could pave the way to new treatments for the disease.

7 Jul 2015

CTI Biotechnology implements Xybion's Pristima 7 Preclinical Suite

Xybion Corporation, leading provider of preclinical R&D solutions announced today that CTI Biotechnology in Suzhou, China has implemented Xybion's Pristima 7 Preclinical Suite. Pristima® was selected after an exhaustive evaluation of top selling preclinical software systems on the market.

30 Jun 2015

Tiny aquatic flatworms could replace existing animal models used in neurotoxicity tests

Laboratories that test chemicals for neurological toxicity could reduce their use of laboratory mice and rats by replacing these animal models with tiny aquatic flatworms known as freshwater planarians.

29 Jun 2015

E2F4 biomarker can help predict prognosis and response to BCG therapy in bladder cancer

Investigators from Dartmouth's Norris Cotton Cancer Center harnessed genomic data to discover that the previously identified E2F4 signature in breast cancer can be utilized to predict prognosis and response to therapy in bladder cancer.

25 Jun 2015

Toxicology News and Research

Latest Toxicology News and Research

Kentucky researcher awarded NCI grant to study potential link between obesity and breast cancer

Embryonic stem cells may help researchers to study physiological effects of environmental pollutants on human health

Roche establishes strategic alliance with Diagnostic Laboratory Services

15th Annual Geriatric Health Care Symposium now open for registration

Novel 3D human skin tissue model could help detect presence of known skin sensitizers in medical device extracts

RGS2 protein plays significant role in healthy egg-sperm union in mice

Innovative approach to treating AAT deficiency

Researchers decode molecular mechanism of fish toxin that has potential to treat cancer

Dartmouth researchers perform first total syntheses of compounds involved in rapid cell death in leukemia

Sulfur dioxide air pollutant can cause adverse effects in asthmatics

Novogen's Anisina granted FDA Orphan Drug Designation for neuroblastoma

Hospitalization rates higher among people who live near hydraulic fracturing wells

Novel gene therapy control system regulates expression of therapeutic transgenes

Study shows that Anisina has potential to improve effectiveness of chemotherapy in children with cancer

Elsevier, NCI implement two-way linking between research articles on ScienceDirect and datasets in caNanoLab

UC Davis scientists identify significant driver of neuropathic pain

Discovery could pave way to new treatments for malaria

CTI Biotechnology implements Xybion's Pristima 7 Preclinical Suite

Tiny aquatic flatworms could replace existing animal models used in neurotoxicity tests

E2F4 biomarker can help predict prognosis and response to BCG therapy in bladder cancer

Forensics and toxicology - Industry Focus eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Toxicology News and Research

Latest Toxicology News and Research

Forensics and toxicology - Industry Focus eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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