Toxicology News and Research

Latest Toxicology News and Research

INTEGRA introduces Row Dilution Plate Holder accessory for VIAFLO 96 and 384 handheld benchtop pipettes

INTEGRA has introduced a Row Dilution Plate Holder accessory for its VIAFLO 96 and 384 handheld benchtop pipettes.

From INTEGRA Biosciences 30 Jun 2014

Study measures hazardous concentrations of carbon monoxide on houseboats

Boaters and marina workers should exercise caution this summer before taking to the seas. A study published online in the Journal of Occupational and Environmental Hygiene (JOEH) outlines hazards posed by carbon monoxide levels on houseboats that use gasoline-powered generators without emission controls, along with controls that are available to reduce exposure to carbon monoxide from the generators.

26 Jun 2014

EnGeneIC plans for Phase 2a trial of EGFR-targeted doxorubicin-packaged EDV nanocells for GBM

EnGeneIC, Ltd., an emerging biopharmaceutical company focused on revolutionizing the treatment of cancer through the targeted delivery of therapeutic agents directly to cancer cells, today announced plans to move forward with a Phase 2a clinical trial in the U.S. using its formulation of EGFR-targeted, EDV nanocells packaged with doxorubicin for the treatment of recurrent glioblastoma (GBM), a common and aggressive type of brain tumor.

26 Jun 2014

Small antioxidant molecules suppress colon cancer associated with colitis

Researchers from Case Western Reserve and Dartmouth universities have shown that a class of small antioxidant molecules carries enormous promise for supressing colon cancer associated with colitis.

25 Jun 2014

Artificial sweetener have potential to limit impact of therapeutic drugs

One of the active ingredients in a popular artificial sweetener could have the potential to limit the impact of therapeutic drugs, reduce the number and balance of beneficial bacteria in the gut and alter hormone secretion, according to an article published in Journal of Toxicology and Environmental Health, Part A: Current Issues.

17 Jun 2014

University of Kentucky receives $12.2 million grant to reduce negative health from hazardous chemicals

The University of Kentucky has received a $12.2 million grant from the National Institutes of Health to continue its work to better understand and minimize negative health and environmental impacts from hazardous waste sites.

17 Jun 2014

Novel microscopy technology helps detect protein that plays key role in prostate cancer

Assemblies of proteins, known as protein complexes, have important functions in cells; protein complexes embedded in the cell membrane, for example, are responsible for the exchange with the extracellular environment.

16 Jun 2014

Synthetic, Enterome partner to study effects of beta-lactam antibiotics on gastrointestinal microflora

Synthetic Biologics, Inc., a developer of novel anti-infective biologic and drug candidates targeting specific pathogens that cause serious infections and diseases, and Enterome Bioscience SA, a pioneer in the development of innovative disease management solutions based on a deep understanding of the gut microbiome, today announced that they have entered into an agreement to conduct metagenomic research on the effects of beta-lactam antibiotics on the gastrointestinal microflora (microbiome) of human patients.

10 Jun 2014

Penn researchers awarded $10 million grant to study adverse health effects, remediation of asbestos

Researchers at the Center of Excellence in Environmental Toxicology, Perelman School of Medicine at the University of Pennsylvania, have been awarded a $10 million grant from the National Institute for Environmental Health Sciences over the next four years to study asbestos exposure pathways that lead to mesothelioma, the bioremediation of this hazardous material, and mechanisms that lead to asbestos-related diseases.

10 Jun 2014

Thrasos presents positive results of THR-184 compound for treatment of acute kidney injury

Thrasos Therapeutics, a biotherapeutics company focused on delivering new solutions for kidney disease, today presented preclinical results showing that its lead development compound THR-184 can effectively protect against loss of kidney function following acute ischemic injury in rat.

4 Jun 2014

Syngene International, Bristol-Myers Squibb extend drug discovery and development collaboration

Bristol-Myers Squibb and Syngene International, India's largest contract research organization, today announced a five-year extension of their drug discovery and development collaboration in India.

3 Jun 2014

P2Y12 and blood clotting: an interview with Dr. Jacobson, NIH

We already understand the many steps involved in blood clotting in great mechanistic detail. The process of blood vessels closing off in response to injury is necessary for preserving life, but blood platelets that are over-active, or activated inappropriately because of unstable plaque, can lead to heart attacks and strokes.

3 Jun 2014

Compound in saliva may protect from toxins in tea, coffee and liquid smoke flavoring

A compound in saliva, along with common proteins in blood and muscle, may protect human cells from powerful toxins in tea, coffee and liquid smoke flavoring, according to results of a new study led by investigators at the Johns Hopkins Kimmel Cancer Center.

2 Jun 2014

Compound in saliva and proteins in blood may protect human cells from powerful toxins in tea, coffee

31 May 2014

Researchers find link between aging and chemicals in environment

Why are some 75-year-olds downright spry while others can barely get around? Part of the explanation, say researchers writing in the Cell Press journal Trends in Molecular Medicine on May 28, is differences from one person to the next in exposure to harmful substances in the environment, chemicals such as benzene, cigarette smoke, and even stress.

29 May 2014

The future of high throughput screening: an interview with Mark Wigglesworth, Director High Throughput Screening, AstraZeneca

Quoting Mike Snowden (VP & Head of Discovery Sciences, AstraZeneca), “it’s where biology meets chemistry”. It’s where for the first time a target protein can be probed for novel molecules that modulate its function, of course we want to do this to prove a hypothesis that these proteins are drug targets with the potential to deliver innovative medicines.

20 May 2014

UH pharmacy students earn awards for excellence in leadership, professional service and clinical skills from TSHP

University of Houston (UH) pharmacy students wrapped up the spring semester with a round of awards for excellence in leadership, professional service and clinical skills.

16 May 2014

Tel Aviv University pinpoints mechanism that causes rare and severe congenital syndrome

In the 1950s and 1960s, pregnant women with morning sickness were often prescribed the new drug thalidomide. Shortly after the medicine was released on the market, a reported 10,000 infants were born with an extreme form of the rare congenital phocomelia syndrome, which caused death in 50 percent of cases and severe physical and mental disabilities in others.

2 May 2014

£1.5M research funding aims to extend imaging techniques, reduce animal use in preclinical research

£1.5m of research funding has been awarded to develop advanced imaging technologies, to maximise their potential to reduce animal use in a diverse range of preclinical research applications.

30 Apr 2014

Hormone disrupting pollutants affecting the development of wild birds along urban rivers

New research indicates that hormone disrupting pollutants are affecting the health and development of wild birds nesting along the urban rivers of South Wales.

30 Apr 2014

Toxicology News and Research

Latest Toxicology News and Research

INTEGRA introduces Row Dilution Plate Holder accessory for VIAFLO 96 and 384 handheld benchtop pipettes

Study measures hazardous concentrations of carbon monoxide on houseboats

EnGeneIC plans for Phase 2a trial of EGFR-targeted doxorubicin-packaged EDV nanocells for GBM

Small antioxidant molecules suppress colon cancer associated with colitis

Artificial sweetener have potential to limit impact of therapeutic drugs

University of Kentucky receives $12.2 million grant to reduce negative health from hazardous chemicals

Novel microscopy technology helps detect protein that plays key role in prostate cancer

Synthetic, Enterome partner to study effects of beta-lactam antibiotics on gastrointestinal microflora

Penn researchers awarded $10 million grant to study adverse health effects, remediation of asbestos

Thrasos presents positive results of THR-184 compound for treatment of acute kidney injury

Syngene International, Bristol-Myers Squibb extend drug discovery and development collaboration

P2Y12 and blood clotting: an interview with Dr. Jacobson, NIH

Compound in saliva may protect from toxins in tea, coffee and liquid smoke flavoring

Compound in saliva and proteins in blood may protect human cells from powerful toxins in tea, coffee

Researchers find link between aging and chemicals in environment

The future of high throughput screening: an interview with Mark Wigglesworth, Director High Throughput Screening, AstraZeneca

UH pharmacy students earn awards for excellence in leadership, professional service and clinical skills from TSHP

Tel Aviv University pinpoints mechanism that causes rare and severe congenital syndrome

£1.5M research funding aims to extend imaging techniques, reduce animal use in preclinical research

Hormone disrupting pollutants affecting the development of wild birds along urban rivers

Forensics and toxicology - Industry Focus eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Toxicology News and Research

Latest Toxicology News and Research

Forensics and toxicology - Industry Focus eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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