Toxicology News and Research

Latest Toxicology News and Research

TxCell demonstrates therapeutic potential of Col-Treg for treatment of autoimmune uveitis

TxCell SA, a biotechnology company developing innovative, economically viable, personalized T cell immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today that TxCell researchers have achieved positive results for Col-Treg, its second product candidate from its ASTrIA platform, in a model of autoimmune uveitis, a leading cause of blindness with very limited treatment options.

28 Oct 2014

Virginia Tech professor developing vaccine that could help smokers overcome nicotine addiction

A Virginia Tech professor is working on a vaccine that could help smokers conquer their nicotine addiction, making many smoking-related diseases and deaths relics of the 21st century.

27 Oct 2014

Newborns of mothers who smoke during pregnancy have altered stress hormones, DNA

Researchers from The Miriam Hospital have studied the effects of smoking during pregnancy and its impact on the stress response in newborn babies. Their research indicates that newborns of mothers who smoke cigarettes during pregnancy show lower levels of stress hormones, lowered stress response, and alterations in DNA for a gene that regulates passage of stress hormones from mother to fetus.

20 Oct 2014

Researchers discover new signaling pathway to fight excess body weight

The number of overweight persons is greatly increasing worldwide - and as a result is the risk of suffering a heart attack, stroke, diabetes or Alzheimer's disease.

16 Oct 2014

Intake of arsenic linked to cardiovascular disease, diabetes

Associated with various types of cancer such as skin and liver, the intake of arsenic it is also linked to cardiovascular disease and diabetes. According to a long-term research conducted by experts from the Center for Research and Advanced Studies it was determined that this metalloid inhibits enzymes associated with antioxidant protection.

16 Oct 2014

Study reveals inner workings of PKA switch that regulates cellular functions, contributes to deadly disorders

A University of Utah-led study using X-rays and neutron beams has revealed the inner workings of a master switch that regulates basic cellular functions, but that also, when mutated, contributes to cancer, cardiovascular disease and other deadly disorders.

13 Oct 2014

Blocking STAT3 in immune system cells increases anti-tumour immunity

The STAT transcription factors are involved in the development of many forms of cancer. STAT3 is frequently activated in tumour cells, so drugs targeting STAT3 could be used in cancer therapy. However, STAT3 is also important in the development of the immune system. Dagmar Gotthardt and colleagues at the Vetmeduni Vienna now show that blocking STAT3 in cells of the immune system actually leads to increased anti-tumour immunity. Anti-STAT3 therapy may thus be highly promising.

13 Oct 2014

Researchers reveal new information about Protein Kinase A

Using X-rays and neutron beams, a team of researchers from the University of California, San Diego School of Medicine, University of Utah and Oak Ridge National Laboratory have teased out new information about Protein Kinase A (PKA), a ubiquitous master switch that helps regulate fundamental cellular functions like energy consumption and interactions with hormones, neurotransmitters and drugs.

10 Oct 2014

VCU receives $6 million grant to develop safe, effective treatments for cocaine addiction

Virginia Commonwealth University has received a five-year, $6 million grant for clinical research and education directed toward the identification, evaluation and development of safe and effective treatments for cocaine addiction.

30 Sep 2014

Research!America to recognize distinguished research advocates with Advocacy Awards

Research!America's 19th annual Advocacy Awards will honor distinguished research advocates who are trailblazers in advancing medical progress to improve the health and economic security of our nation. The event will take place on Wednesday, March 11, 2015, at the Andrew W. Mellon Auditorium in Washington, DC.

30 Sep 2014

Pitt researchers awarded new $5.8 million NIH grant to develop microfluidic 3D liver model system

With a new $5.8 million, three-year award from the National Institutes of Health, researchers at the University of Pittsburgh School of Medicine will further develop a state-of-the-art, microfluidic 3D model system that mimics structure and function of the liver to better predict organ physiology, assess drug toxicity and build disease models.

25 Sep 2014

Prioritizing scientific research to understand risks of PPCPs in the environment

In 2011 the Society of Environmental Toxicology and Chemistry held a workshop for 45 international experts to identify and prioritize the scientific research needed to understand the risks of pharmaceuticals and personal care products (PPCPs) in the environment.

24 Sep 2014

Adding common epilepsy drug to morphine can result in better pain control, say IU researchers

Adding a common epilepsy drug to a morphine regimen can result in better pain control with fewer side effects. Moreover, the combination can reduce the dosage of the opioid needed to be effective, according to a team of pain researchers at Indiana University.

17 Sep 2014

Zebrafish may hold key to unlocking a leading cause of respiratory diseases

A small freshwater fish found in many tropical aquariums may hold the key to unlocking one of the leading causes of respiratory diseases in humans.

17 Sep 2014

Complete analysis of the global stem cell market

BCC Research reveals in its new report, THE GLOBAL MARKET FOR STEM CELLS, the global market for stem cells is expected to grow to nearly $10.6 billion by 2018, with a five-year compound annual growth rate (CAGR) of 13.6%.

16 Sep 2014

New project aims at delivering innovative test to improve safety of chemical products, drugs

The Genotrace project, combining targeted research and technology transfer, aims at delivering an innovative test to improve the safety of chemical products, drugs, human and animal food and the environment.

10 Sep 2014

Scanning electron microscope for 3D volume imaging of cells and tissues announced by FEI

FEI (NASDAQ: FEIC) announced today its new Teneo VS™ scanning electron microscope (SEM), which offers a VolumeScope™ capability for life science applications. The Teneo platform tightly integrates FEI’s latest-generation SEM with VolumeScope, an in-chamber microtome and proprietary analytical software to provide fully-automated, large-volume reconstructions with dramatically improved z-axis resolution.

From Thermo Fisher Scientific – Electron Microscopy Solutions 4 Sep 2014

ANP reports primary efficacy results from ATL1103 Phase II trial in patients with acromegaly

Antisense Therapeutics Limited is pleased to report the primary efficacy results from its Phase II clinical trial of ATL1103 in patients with the potentially life threatening growth disorder, acromegaly.

2 Sep 2014

Synthetic announces positive results from final preclinical toxicology study of SYN-004

Synthetic Biologics, Inc., a developer of novel anti-infective biologic and drug candidates targeting specific pathogens that cause serious infections and diseases, announced today positive results from its final preclinical toxicology study of SYN-004.

2 Sep 2014

Ames test successfully adapted for use with cigarette smoke and other complex aerosols

The Ames test, a widely used method to determine whether a chemical has the potential to cause cancer, has been successfully adapted for use with cigarette smoke and other complex aerosols.

27 Aug 2014

Toxicology News and Research

Latest Toxicology News and Research

TxCell demonstrates therapeutic potential of Col-Treg for treatment of autoimmune uveitis

Virginia Tech professor developing vaccine that could help smokers overcome nicotine addiction

Newborns of mothers who smoke during pregnancy have altered stress hormones, DNA

Researchers discover new signaling pathway to fight excess body weight

Intake of arsenic linked to cardiovascular disease, diabetes

Study reveals inner workings of PKA switch that regulates cellular functions, contributes to deadly disorders

Blocking STAT3 in immune system cells increases anti-tumour immunity

Researchers reveal new information about Protein Kinase A

VCU receives $6 million grant to develop safe, effective treatments for cocaine addiction

Research!America to recognize distinguished research advocates with Advocacy Awards

Pitt researchers awarded new $5.8 million NIH grant to develop microfluidic 3D liver model system

Prioritizing scientific research to understand risks of PPCPs in the environment

Adding common epilepsy drug to morphine can result in better pain control, say IU researchers

Zebrafish may hold key to unlocking a leading cause of respiratory diseases

Complete analysis of the global stem cell market

New project aims at delivering innovative test to improve safety of chemical products, drugs

Scanning electron microscope for 3D volume imaging of cells and tissues announced by FEI

ANP reports primary efficacy results from ATL1103 Phase II trial in patients with acromegaly

Synthetic announces positive results from final preclinical toxicology study of SYN-004

Ames test successfully adapted for use with cigarette smoke and other complex aerosols

Forensics and toxicology - Industry Focus eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Toxicology News and Research

Latest Toxicology News and Research

Forensics and toxicology - Industry Focus eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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