Toxicology News and Research

Latest Toxicology News and Research

Researchers evaluate lung-related health impacts associated with engineered nanomaterials

For the first time, researchers from institutions around the country have conducted an identical series of toxicology tests evaluating lung-related health impacts associated with widely used engineered nanomaterials (ENMs).

7 May 2013

Expert to explain how drugs induce damage to DNA in public lecture on May 16

Anticancer drugs save lives and/or improve the quality of life for many cancer patients. Many anti-cancer drugs work by killing tumor cells after inducing damage to DNA.

4 May 2013

Preclinical data of Emergent BioSolutions' ES414 in mCRPC presented at PEGS 2013

Emergent BioSolutions Inc. today announced that it presented preclinical data on its lead bispecific ADAPTIRTM (Modular Protein Technology) molecule, ES414, at the 9th Annual Protein and Antibody Engineering Summit, currently underway in Boston, MA.

3 May 2013

Shin Poong to develop, market Almac Discovery's ALM201 in South Korea

Almac Discovery today announced the licensing of its novel anti-angiogenic peptide ALM201 to Shin Poong Pharmaceutical Company Ltd for clinical development and marketing in South Korea.

29 Apr 2013

Study examines health issues of residents living nearby drilling operations

Residents living in areas near natural gas operations, also known as hydraulic fracturing, or fracking, are concerned their illnesses may be a result of nearby drilling operations.

29 Apr 2013

Convergence starts Phase II proof of concept study with CNV2197944 in pain associated with PHN

Convergence Pharmaceuticals Limited, the company focused on the development of novel and high value analgesic medicines for the treatment of chronic pain, today announces that it has started a Phase II proof of concept study with CNV2197944 in pain associated with post-herpetic neuralgia.

24 Apr 2013

Researchers decode toggle switch that can stimulate fat burning

For a long time, scientists have dreamt of converting undesirable white fat cells into brown fat cells and thus simply have excess pounds melt away. Researchers at the University of Bonn have now gotten a step closer to this goal: They decoded a "toggle switch" in mice which can significantly stimulate fat burning.

24 Apr 2013

Working or travelling continuously on underground railway can have damaging effects on health

New research from the University of Southampton has found that working or travelling on an underground railway for a sustained period of time could have health implications.

24 Apr 2013

Exposure to chemical pesticide has impacts that span multiple generations, say researchers

North Carolina State University researchers studying aquatic organisms called Daphnia have found that exposure to a chemical pesticide has impacts that span multiple generations - causing the so-called "water fleas" to produce more male offspring, and causing reproductive problems in female offspring.

23 Apr 2013

Aurigene and Endo’s collaborative efforts yield novel drug candidates

Aurigene and Endo entered into collaboration in 2009, for multiple integrated drug discovery programs in the areas of Inflammation and Oncology.

22 Apr 2013

Study highlights importance of zebrafish as a model organism for human disease research

Researchers demonstrate today that 70 per cent of protein-coding human genes are related to genes found in the zebrafish and that 84 per cent of genes known to be associated with human disease have a zebrafish counterpart.

18 Apr 2013

Tacere Therapeutics submits TT-034 clinical trial application to Recombinant DNA Advisory Committee

RNAi-based therapeutics company Benitec Biopharma Limited today announced that the company's wholly owned US subsidiary, Tacere Therapeutics Inc., has submitted an application to the US National Institutes of Health's Recombinant DNA Advisory Committee.

18 Apr 2013

Women with sufficient amounts of vitamin D less likely to develop uterine fibroids

Women who had sufficient amounts of vitamin D were 32 percent less likely to develop fibroids than women with insufficient vitamin D, according to a study from researchers at the National Institutes of Health.

16 Apr 2013

New research shows safety can be improved for people participating in medical experiments

In almost 90 per cent of cases, novel drugs tested on humans by pharmaceutical companies do not work as intended and must be scrapped. Often the drugs do not work, while at worst, test subjects die. New research from the University of Southern Denmark now shows that this number can be reduced.

12 Apr 2013

Lipid Therapeutics to proceed with US LT-02 Phase III trial for mild-moderate ulcerative colitis

Lipid Therapeutics announces today that it has successfully filed its first US IND for its lead product LT-02 and is now in a position to proceed with a planned Phase III trial in the US in mild-moderate ulcerative colitis patients. The LT-02 IND was subject to the FDA's customary 30 day review period.

11 Apr 2013

Nektar Therapeutics presents positive results for NKTR-214 at AACR Annual Meeting

Nektar Therapeutics today presented positive preclinical data for NKTR-214, a novel cancer immunotherapy which targets the IL-2 receptor complex, at the 2013 American Association for Cancer Research Annual Meeting.

8 Apr 2013

Sildenafil may also serve as weight loss aid, shows new research

Although sildenafil is best known for promoting erections, it may also serve as a weight loss aid by coaxing our bodies to store more healthy "brown fat" relative to unhealthy "white fat" than it would otherwise do on its own.

2 Apr 2013

Life Technologies signs distribution agreement with LGC Forensics for ParaDNA system

As the global market leader in human identification, Life Technologies Corporation announced today it signed a global exclusive agreement with LGC Forensics for the right to distribute ParaDNA, a portable rapid DNA system that determines the quality of human DNA faster and more economically than any existing method.

1 Apr 2013

Recent findings reveal correlations between autism prevalence, childhood vaccination

Recent finds in two articles in the Journal of Toxicology and Environmental Health, Part A indicate correlations between autism and vaccinations.

30 Mar 2013

Johns Hopkins scientists identify DNA-damaging substances in food

In a laboratory study pairing food chemistry and cancer biology, scientists at the Johns Hopkins Kimmel Cancer Center tested the potentially harmful effect of foods and flavorings on the DNA of cells.

28 Mar 2013

Toxicology News and Research

Latest Toxicology News and Research

Researchers evaluate lung-related health impacts associated with engineered nanomaterials

Expert to explain how drugs induce damage to DNA in public lecture on May 16

Preclinical data of Emergent BioSolutions' ES414 in mCRPC presented at PEGS 2013

Shin Poong to develop, market Almac Discovery's ALM201 in South Korea

Study examines health issues of residents living nearby drilling operations

Convergence starts Phase II proof of concept study with CNV2197944 in pain associated with PHN

Researchers decode toggle switch that can stimulate fat burning

Working or travelling continuously on underground railway can have damaging effects on health

Exposure to chemical pesticide has impacts that span multiple generations, say researchers

Aurigene and Endo’s collaborative efforts yield novel drug candidates

Study highlights importance of zebrafish as a model organism for human disease research

Tacere Therapeutics submits TT-034 clinical trial application to Recombinant DNA Advisory Committee

Women with sufficient amounts of vitamin D less likely to develop uterine fibroids

New research shows safety can be improved for people participating in medical experiments

Lipid Therapeutics to proceed with US LT-02 Phase III trial for mild-moderate ulcerative colitis

Nektar Therapeutics presents positive results for NKTR-214 at AACR Annual Meeting

Sildenafil may also serve as weight loss aid, shows new research

Life Technologies signs distribution agreement with LGC Forensics for ParaDNA system

Recent findings reveal correlations between autism prevalence, childhood vaccination

Johns Hopkins scientists identify DNA-damaging substances in food

Forensics and toxicology - Industry Focus eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Toxicology News and Research

Latest Toxicology News and Research

Forensics and toxicology - Industry Focus eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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