Toxicology News and Research

Latest Toxicology News and Research

Sangamo BioSciences signs definitive agreement to buy Ceregene

Sangamo BioSciences, Inc. announced that it signed a definitive agreement to acquire Ceregene, Inc., a privately held biotechnology company focused on developing adeno-associated virus gene therapies.

26 Aug 2013

BARDA Awards Novan $7.8M To Develop Thermal Burns Treatment

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26 Aug 2013

3-D structure of proteins show flame retardants can mimic estrogen hormones

By determining the three-dimensional structure of proteins at the atomic level, researchers at the National Institutes of Health have discovered how some commonly used flame retardants, called brominated flame retardants (BFRs), can mimic estrogen hormones and possibly disrupt the body's endocrine system. BFRs are chemicals added or applied to materials to slow or prevent the start or growth of fire.

20 Aug 2013

Flavonoids in celery, artichokes induce apoptosis in human pancreatic cancer cells

Celery, artichokes, and herbs, especially Mexican oregano, all contain apigenin and luteolin, flavonoids that kill human pancreatic cancer cells in the lab by inhibiting an important enzyme, according to two new University of Illinois studies.

16 Aug 2013

New test hints 3 sodas daily hurt lifespan, reproduction in mice

When mice ate a diet of 25 percent extra sugar - the mouse equivalent of a healthy human diet plus three cans of soda daily - females died at twice the normal rate and males were a quarter less likely to hold territory and reproduce, according to a toxicity test developed at the University of Utah.

14 Aug 2013

Study reveals cancer in humans linked with high amounts of proteins responsible for cells division

Cancer in humans is frequently associated with unusually high amounts of one or more proteins responsible for controlling the rate at which cells divide. As an example, excessive amounts of the cyclin-dependent kinase CDK6 are often found in types of cancer such as lymphoma.

14 Aug 2013

Chemicals added to swimming pool water can cause irritation, injury and even death, doctors warn

Chemicals are added to swimming pool water to enhance and protect the water quality and minimize disease-causing germs, but these same chemicals can cause irritation, injury and even death when not handled appropriately, doctors at Vanderbilt University Medical Center warn.

1 Aug 2013

Kentucky researcher receives 2013 Discovery Award from Society for Free Radical Biology & Medicine

The Society for Free Radical Biology & Medicine recently named the University of Kentucky's Dr. Allan Butterfield as the recipient of its 2013 Discovery Award.

30 Jul 2013

Fried fish fingers generate more furanic compounds than those baked in oven

Spanish and Portuguese researchers have discovered that fried fish fingers generate more furanic compounds than those baked in the oven. To be precise, there are three times as many when fried with olive oil and twice as many with sunflower oil. These compounds improve the food's organoleptic characteristics, but are believed to be toxic and carcinogenic.

26 Jul 2013

STED-RICS microscopy method records rapid movements of molecules in live samples

The newly developed STED-RICS microscopy method records rapid movements of molecules in live samples. By combining raster image correlation spectroscopy (RICS) with STED fluorescence microscopy, researchers of Karlsruhe Institute of Technology (KIT) opened up new applications in medical research, e.g. analyzing the dynamics of cell membranes at high protein concentrations.

25 Jul 2013

EU-funded project examines dietary habits in people with inadequate nutrition

Until now, we have had very little understanding of the extent of malnutrition in Europe, especially in populations at risk of poverty. Now, an EU-funded project calledCHANCE, aims to address the dietary habits in people with inadequate nutrition.

20 Jul 2013

Whittier IPA signs agreement with Alere Accountable Care Solutions to build community-wide HIE

Whittier Independent Practice Association, of Newburyport, Massachusetts, announced that it has signed an agreement with Alere Accountable Care Solutions to build a community-wide health information exchange.

20 Jul 2013

WuXi buys Provantis Portal Remote Study Monitoring solution from Instem

Instem, a leading provider of IT solutions to the global early development healthcare market, announced today that WuXi AppTec, a leading supplier of R&D services to the pharmaceutical, biotechnology, and medical device industries with operations in China and the United States, has purchased the Provantis Portal Remote Study Monitoring solution.

19 Jul 2013

Scientists set out to develop safer versions of acetaminophen

Efforts to develop a safer form of acetaminophen - the pain and fever-reducer that is one of the most widely used drugs - have led to discovery of substances that may have less potentially toxic effects on the liver. A report on the research appears in ACS Medicinal Chemistry Letters.

12 Jul 2013

Seven named recipients of GSA poster awards at 19th International C. elegans Meeting

Six graduate students and one undergraduate were named as recipients of Genetics Society of America poster awards at the 19th International C. elegans Meeting, held June 26 on the campus of the University of California, Los Angeles.

12 Jul 2013

Study shows cigarette smoke inhibits activity of key genes that protect heart and lungs

New insights into why obese cigarette smokers experience a high risk of heart disease suggest that cigarette smoke affects the activity of hundreds of key genes that both protect the heart and lungs and expose them to damage.

11 Jul 2013

Soy peptide injection dramatically reduces colon cancer metastasis in mice

After a recent University of Illinois study showed that injection of the soy peptide lunasin dramatically reduced colon cancer metastasis in mice, the researchers were eager to see how making lunasin part of the animals' daily diet would affect the spread of the disease.

9 Jul 2013

p53 restoration of function drug candidate: an interview with Dr. Wayne Danter, MD, FRCPC President and CEO of Critical Outcome Technologies

COTI-2 is a computer-designed small molecule that was discovered by our artificial intelligence drug discovery platform called CHEMSAS.

8 Jul 2013

Father's lifestyle has potential to affect DNA of multiple generations

Gene mutations caused by a father's lifestyle can be inherited by his children, even if those mutations occurred before conception. What's more, these findings show that mutations in the germ-line are present in all cells of the children, including their own germ cells. This means that a father's lifestyle has the potential to affect the DNA of multiple generations and not just his immediate offspring. These findings were published in the July 2013 issue of The FASEB Journal.

2 Jul 2013

Low doses of arsenic and estrogen can cause cancer in prostate cells, study finds

Science knows that arsenic and estrogen can cause cancer. At certain very low levels, the chemicals offer little to no threats to human health.

29 Jun 2013

Toxicology News and Research

Latest Toxicology News and Research

Sangamo BioSciences signs definitive agreement to buy Ceregene

BARDA Awards Novan $7.8M To Develop Thermal Burns Treatment

3-D structure of proteins show flame retardants can mimic estrogen hormones

Flavonoids in celery, artichokes induce apoptosis in human pancreatic cancer cells

New test hints 3 sodas daily hurt lifespan, reproduction in mice

Study reveals cancer in humans linked with high amounts of proteins responsible for cells division

Chemicals added to swimming pool water can cause irritation, injury and even death, doctors warn

Kentucky researcher receives 2013 Discovery Award from Society for Free Radical Biology & Medicine

Fried fish fingers generate more furanic compounds than those baked in oven

STED-RICS microscopy method records rapid movements of molecules in live samples

EU-funded project examines dietary habits in people with inadequate nutrition

Whittier IPA signs agreement with Alere Accountable Care Solutions to build community-wide HIE

WuXi buys Provantis Portal Remote Study Monitoring solution from Instem

Scientists set out to develop safer versions of acetaminophen

Seven named recipients of GSA poster awards at 19th International C. elegans Meeting

Study shows cigarette smoke inhibits activity of key genes that protect heart and lungs

Soy peptide injection dramatically reduces colon cancer metastasis in mice

p53 restoration of function drug candidate: an interview with Dr. Wayne Danter, MD, FRCPC President and CEO of Critical Outcome Technologies

Father's lifestyle has potential to affect DNA of multiple generations

Low doses of arsenic and estrogen can cause cancer in prostate cells, study finds

Forensics and toxicology - Industry Focus eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Toxicology News and Research

Latest Toxicology News and Research

Forensics and toxicology - Industry Focus eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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