Toxicology News and Research

Latest Toxicology News and Research

Study reveals how cocaine permanently damages proteins in the body

A new study on cocaine, the notorious white powder illegally snorted, injected or smoked by nearly 2 million Americans, details how it may permanently damage proteins in the body. That information, gleaned from laboratory tests, could be used to potentially detect the drug in biofluids for weeks or months - instead of days - after use, say scientists. The findings, which appear in the ACS journal Chemical Research in Toxicology, could also help explain cocaine's long-term health effects.

14 Nov 2013

Sanford-Burnham scientists receive grant to assess potential toxicity of large collections of chemicals

A bicoastal group of scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) was recently awarded a three-year grant from the U.S. Department of the Air Force to assess the potential toxicity of large collections of chemicals.

13 Nov 2013

FOXO3 transcription factor may protect against alcohol-induced liver injury

New data suggest that the transcription factor FOXO3 may protect against alcohol-induced liver injury. Researchers determined that alcohol given to mice deficient in FOXO3 caused severe liver injury resembling human alcoholic hepatitis.

11 Nov 2013

Study reveals that lower dose of BPA contributes to large range of health problems in humans

Bisphenol A (BPA) is a known endocrine disruptor that hijacks the normal responses of hormones. Yet, traditional toxicology studies indicate that only very high doses of this chemical affect exposed animals-doses as high as 50 mg/kg/day.

8 Nov 2013

FDA issues GRAS Letters of No Objection for Morinaga's proprietary probiotic strain

Morinaga Milk Industry Co., Ltd., the second largest dairy product company in Japan, today announced that the U.S. Food and Drug Administration has issued Generally Recognized as Safe Letters of No Objection for Morinaga's proprietary probiotic strain, Bifidobacterium breve M-16V for food applications and infant formulas.

6 Nov 2013

Reviva announces successful completion of End-of-Phase 2 meeting for RP5063 drug

Reviva Pharmaceuticals, Inc., a privately held pharmaceutical company focused on the discovery and development of new, safer and highly effective therapies for chronic indications, announced today the successful completion of an End-of-Phase 2 meeting with the Food and Drug Administration for its lead, new investigational antipsychotic drug, RP5063.

5 Nov 2013

Research: Neurotoxin provides more relief from pain in dogs with bone cancer

By the time bone cancer is diagnosed in a pet dog, it is often too late to save the animal's life. Instead, the goal of treatment is to keep the dog as comfortable and free of pain as possible for as long as possible.

25 Oct 2013

NanoViricides’ FluCide drug candidate found to be well tolerated in non-GLP safety/toxicology study

NanoViricides, Inc. (the "Company") reports that its optimized injectable FluCide® drug candidate was found to be well tolerated in a non-GLP small animal safety/toxicology study. This study is an important step in the drug development pathway for FluCide.

21 Oct 2013

Researchers to present latest findings in emergency medicine research at ACEP13-Scientific Assembly

Leading researchers in emergency medicine will present more than 400 studies during ACEP13-Scientific Assembly, the annual meeting of the American College of Emergency Physicians in Seattle, Washington.

15 Oct 2013

Scientists decode key molecular gateway for toxin that causes botulism

U.S. and German scientists have decoded a key molecular gateway for the toxin that causes botulism, pointing the way to treatments that can keep the food-borne poison out of the bloodstream.

12 Oct 2013

Arrowhead initiates Phase 1 study of ARC-520 for treatment against chronic HBV infection

Arrowhead Research Corporation (NASDAQ: ARWR), a biopharmaceutical company developing targeted RNAi therapeutics, today announced that it completed enrollment in a Phase 1 clinical trial of ARC-520, its RNAi-based candidate against chronic hepatitis B virus infection.

9 Oct 2013

Selenium in plants causes mortality and delays development in honey bee, say researchers

Traditionally, honey bee research has focused on environmental stressors such as pesticides, pathogens and diseases. Now a research team led by entomologists at the University of California, Riverside has published a study that focuses on an anthropogenic pollutant: selenium (Se).

4 Oct 2013

Study shows PTSD increases individual's risk of metabolic syndrome

People suffering from post-traumatic stress disorder (PTSD) face a greater risk of cardiovascular disease and death. A new study involving a comprehensive review of the medical literature shows that PTSD also increases an individual's risk of metabolic syndrome.

3 Oct 2013

Designing safer titanium dioxide for human use

Using a particular type of titanium dioxide - a common ingredient in cosmetics, food products, toothpaste and sunscreen - could reduce the potential health risks associated with the widely used compound. The report on the substance, produced by the millions of tons every year for the global market, appears in the ACS journal Chemical Research in Toxicology.

26 Sep 2013

Exposure to cocaine during in utero development causes disruptions in normal brain development

Prenatal cocaine exposure affects both behavior and brain. Animal studies have shown that exposure to cocaine during in utero development causes numerous disruptions in normal brain development and negatively affects behavior from birth and into adulthood.

25 Sep 2013

Study: French horn players are one of the most at-risk groups of developing NIHL

Professional French horn players may need to seriously consider adopting effective strategies to prevent noise induced hearing loss (NIHL). A new study published online in the Journal of Occupational and Environmental Hygiene (JOEH) found further evidence that French horn players are one of the most at-risk groups of developing NIHL among professional orchestral musicians.

25 Sep 2013

Study on tempol impacted gut bacteria may lead to new treatments for obesity

A drug that appears to target specific intestinal bacteria in the guts of mice may create a chain reaction that could eventually lead to new treatments for obesity and diabetes in humans, according to a team of researchers.

25 Sep 2013

Engineered nanomaterials inhalation negatively impacts gestational development in animal models

After a decade of rapidly growing industrial use, unimaginably tiny particles surround us everywhere, every day, in everything we do. Used in the manufacturing of cosmetics, clothing, paints, food, drug delivery systems and many other familiar products we all use daily, little is known about the effects these materials have on health.

25 Sep 2013

UNC receives grants from FDA and NIH to establish Tobacco Centers of Regulatory Science

The University of North Carolina at Chapel Hill received two separate grants from the U.S. Food and Drug Administration and the National Institutes of Health today as part of an on-going interagency partnership. UNC will house two of 14 Tobacco Centers of Regulatory Science, which are receiving a total of up to $53 million for tobacco-related research in fiscal year 2013.

21 Sep 2013

Ernest Mario School of Pharmacy, Robert Wood Johnson Medical School to launch dual-degree program

A dual-degree program combining a doctorate in pharmacy with a medical degree has been developed by Rutgers University's Robert Wood Johnson Medical School and Ernest Mario School of Pharmacy.

21 Sep 2013

Toxicology News and Research

Latest Toxicology News and Research

Study reveals how cocaine permanently damages proteins in the body

Sanford-Burnham scientists receive grant to assess potential toxicity of large collections of chemicals

FOXO3 transcription factor may protect against alcohol-induced liver injury

Study reveals that lower dose of BPA contributes to large range of health problems in humans

FDA issues GRAS Letters of No Objection for Morinaga's proprietary probiotic strain

Reviva announces successful completion of End-of-Phase 2 meeting for RP5063 drug

Research: Neurotoxin provides more relief from pain in dogs with bone cancer

NanoViricides’ FluCide drug candidate found to be well tolerated in non-GLP safety/toxicology study

Researchers to present latest findings in emergency medicine research at ACEP13-Scientific Assembly

Scientists decode key molecular gateway for toxin that causes botulism

Arrowhead initiates Phase 1 study of ARC-520 for treatment against chronic HBV infection

Selenium in plants causes mortality and delays development in honey bee, say researchers

Study shows PTSD increases individual's risk of metabolic syndrome

Designing safer titanium dioxide for human use

Exposure to cocaine during in utero development causes disruptions in normal brain development

Study: French horn players are one of the most at-risk groups of developing NIHL

Study on tempol impacted gut bacteria may lead to new treatments for obesity

Engineered nanomaterials inhalation negatively impacts gestational development in animal models

UNC receives grants from FDA and NIH to establish Tobacco Centers of Regulatory Science

Ernest Mario School of Pharmacy, Robert Wood Johnson Medical School to launch dual-degree program

Forensics and toxicology - Industry Focus eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Toxicology News and Research

Latest Toxicology News and Research

Forensics and toxicology - Industry Focus eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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